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Professor Stuart Tangye

Professor Stuart Tangye

Conjoint Professor
Medicine & Health
School of Clinical Medicine

Fields of research: Immunology

Research Interests: Human immunology, cellular immunology, primary immunodeficiencies

Qualifications: B App Sci (hons), PhD

Society & Memberships: Australasian Society of Immunology, Australasion Society of Clinical Immunology and Allergy, AAI, Henry Kunkel Society

Phone
02 9295 8455
Location
Garvan Institute of Medical Research 384 Victoria Street DARLINGHURST NSW 2010
  • Book Chapters | 2024
    Tangye SG; Casanova J-L; Ma CS, 2024, 'Human Immunodeficiencies Caused by Inborn Errors of B-Cell Development or Function', in Molecular Biology of B Cells, Elsevier, pp. 335 - 365,
    Book Chapters | 2010
    Tangye SG; Fulcher DA, 2010, 'The Role of BAFF and APRIL in Regulating Human B-Cell Behaviour: Implications for Disease Pathogenesis', in Cancro MP (ed.), BLYS LIGANDS AND RECEPTORS, HUMANA PRESS INC, pp. 195 - 220,
    Book Chapters | 2010
    Tangye SG; Fulcher DA, 2010, 'The role of BAFF and APRIL in regulating human B-cell behaviour: implications for disease pathogenesis', in Cancro MP (ed.), BLys Ligands and Receptors, Humana Press, pp. 195 - 220,
    Book Chapters | 2006
    TANGYE S; MACKAY F, 2006, 'CHAPTER 11 B Cells and Autoimmunity', in The Autoimmune Diseases, Elsevier, pp. 139 - 156,
    Book Chapters | 2002
    Nichols KE; Tangye SG, 2002, 'Src Homology 2 Domain‐Containing Gene 1 A ( SH2D1A )', in , Wiley,
    Book Chapters | 2002
    Nichols KE; Tangye SG, 2002, 'Signaling Lymphocytic Activation Molecule (SLAM)', in , Wiley,
  • Journal articles | 2025
    Shadur B; NasserEddin A; Zaidman I; Schejter YD; Even-Or E; Berkun Y; Meyts I; Hmedat H; Sulaiman A; Tangye SG; Stepensky P, 2025, 'Successful Haematopoietic Stem Cell Transplantation for LRBA Deficiency with Fludarabine, Treosulfan, and Thiotepa-Based Conditioning', Journal of Clinical Immunology, 45,
    Journal articles | 2024
    Arango-Franco CA; Ogishi M; Unger S; Delmonte OM; Orrego JC; Yatim A; Velasquez-Lopera MM; Zea-Vera AF; Bohlen J; Chbihi M; Fayand A; Sánchez JP; Rojas J; Seeleuthner Y; Le Voyer T; Philippot Q; Payne KJ; Gervais A; Erazo-Borrás LV; Correa-Londoño LA; Cederholm A; Gallón-Duque A; Goncalves P; Doisne JM; Horev L; Charmeteau-De Muylder B; Álvarez J; Arboleda DM; Pérez-Zapata L; Vásquez-Echeverri E; Moncada-Vélez M; López JA; Caicedo Y; Palterer B; Patiño PJ; Montoya CJ; Chaldebas M; Zhang P; Nguyen T; Ma CS; Jeljeli M; Alzate JF; Cabarcas F; Khan T; Rinchai D; Prétet JL; Boisson B; Marr N; Ibrahim R; Molho-Pessach V; Boisson-Dupuis S; Kiritsi D; Barata JT; Landegren N; Neven B; Abel L; Lisco A; Béziat V; Jouanguy E; Bustamante J; Di Santo JP; Tangye SG; Notarangelo LD; Cheynier R; Natsuga K; Arias AA; Franco JL; Warnatz K; Casanova JL; Puel A, 2024, 'IL-7–dependent and –independent lineages of IL-7R–dependent human T cells', Journal of Clinical Investigation, 134,
    Journal articles | 2024
    Arias AA; Neehus AL; Ogishi M; Meynier V; Krebs A; Lazarov T; Lee AM; Arango-Franco CA; Yang R; Orrego J; Corcini Berndt M; Rojas J; Li H; Rinchai D; Erazo-Borrás L; Han JE; Pillay B; Ponsin K; Chaldebas M; Philippot Q; Bohlen J; Rosain J; Le Voyer T; Janotte T; Amarajeeva K; Soudée C; Brollo M; Wiegmann K; Marquant Q; Seeleuthner Y; Lee D; Lainé C; Kloos D; Bailey R; Bastard P; Keating N; Rapaport F; Khan T; Moncada-Vélez M; Carmona MC; Obando C; Alvarez J; Cataño JC; Martínez-Rosado LL; Sanchez JP; Tejada-Giraldo M; L’Honneur AS; Agudelo ML; Perez-Zapata LJ; Arboleda DM; Alzate JF; Cabarcas F; Zuluaga A; Pelham SJ; Ensser A; Schmidt M; Velásquez-Lopera MM; Jouanguy E; Puel A; Krönke M; Ghirardello S; Borghesi A; Pahari S; Boisson B; Pittaluga S; Ma CS; Emile JF; Notarangelo LD; Tangye SG; Marr N; Lachmann N; Salvator H; Schlesinger LS; Zhang P; Glickman MS; Nathan CF; Geissmann F; Abel L; Franco JL; Bustamante J; Casanova JL; Boisson-Dupuis S, 2024, 'Tuberculosis in otherwise healthy adults with inherited TNF deficiency', Nature, 633, pp. 417 - 425,
    Journal articles | 2024
    Bohlen J; Bagarić I; Vatovec T; Ogishi M; Ahmed SF; Cederholm A; Buetow L; Sobrino S; Floc’h CL; Arango-Franco CA; Seabra L; Michelet M; Barzaghi F; Leardini D; Saettini F; Vendemini F; Baccelli F; Catala A; Gambineri E; Veltroni M; la Red YAD; Rice GI; Consonni F; Berteloot L; Largeaud L; Conti F; Roullion C; Masson C; Bessot B; Seeleuthner Y; Le Voyer T; Rinchai D; Rosain J; Neehus AL; Erazo-Borrás L; Li H; Janda Z; Cho EJ; Muratore E; Soudée C; Lainé C; Delabesse E; Goulvestre C; Ma CS; Puel A; Tangye SG; André I; Bole-Feysot C; Abel L; Erlacher M; Zhang SY; Béziat V; Lagresle-Peyrou C; Six E; Pasquet M; Alsina L; Aiuti A; Zhang P; Crow YJ; Landegren N; Masetti R; Huang DT; Casanova JL; Bustamante J, 2024, 'Autoinflammation in patients with leukocytic CBL loss of heterozygosity is caused by constitutive ERK-mediated monocyte activation', Journal of Clinical Investigation, 134,
    Journal articles | 2024
    Gardner LS; Vaughan L; Avery DT; Meyts I; Ma CS; Tangye SG; Varikatt W; Lin MW, 2024, 'Development of EBV Related Diffuse Large B-cell Lymphoma in Deficiency of Adenosine Deaminase 2 with Uncontrolled EBV Infection', Journal of Clinical Immunology, 44,
    Journal articles | 2024
    Gervais A; Bastard P; Bizien L; Delifer C; Tiberghien P; Rodrigo C; Trespidi F; Angelini M; Rossini G; Lazzarotto T; Conti F; Cassaniti I; Baldanti F; Rovida F; Ferrari A; Mileto D; Mancon A; Abel L; Puel A; Cobat A; Rice CM; Cadar D; Schmidt-Chanasit J; Scheid JF; Lemieux JE; Rosenberg ES; Agudelo M; Tangye SG; Borghesi A; Durand GA; Duburcq-Gury E; Valencia BM; Lloyd AR; Nagy A; MacDonald MM; Simonin Y; Zhang S-Y; Casanova J-L, 2024, 'Auto-Abs neutralizing type I IFNs in patients with severe Powassan, Usutu, or Ross River virus disease.', J Exp Med, 221,
    Journal articles | 2024
    Guérin A; Moncada-Vélez M; Jackson K; Ogishi M; Rosain J; Mancini M; Langlais D; Nunez A; Webster S; Goyette J; Khan T; Marr N; Avery DT; Rao G; Waterboer T; Michels B; Neves E; Morais CI; London J; Mestrallet S; Maire PQD; Neven B; Rapaport F; Seeleuthner Y; Lev A; Simon AJ; Montoya J; Barel O; Gómez-Rodríguez J; Orrego JC; L’honneur AS; Soudée C; Rojas J; Velez AC; Sereti I; Terrier B; Marin N; García LF; Abel L; Boisson-Dupuis S; Reis J; Marinho A; Lisco A; Faria E; Goodnow CC; Vasconcelos J; Béziat V; Ma CS; Somech R; Casanova JL; Bustamante J; Franco JL; Tangye SG, 2024, 'Helper T cell immunity in humans with inherited CD4 deficiency', Journal of Experimental Medicine, 221,
    Journal articles | 2024
    Huynh A; Gray PE; Sullivan A; Mackie J; Guerin A; Rao G; Pathmanandavel K; Mina ED; Hollway G; Hobbs M; Enthoven K; O’Young P; McManus S; Wainwright LH; Higgins M; Noon F; Wong M; Bastard P; Zhang Q; Casanova JL; Hsiao KC; Pinzon-Charry A; Ma CS; Tangye SG, 2024, 'A Novel Case of IFNAR1 Deficiency Identified a Common Canonical Splice Site Variant in DOCK8 in Western Polynesia: The Importance of Validating Variants of Unknown Significance in Under-Represented Ancestries', Journal of Clinical Immunology, 44,
    Journal articles | 2024
    Le Voyer T; Maglorius Renkilaraj MRL; Moriya K; Lorenzo MP; Nguyen T; Gao L; Rubin T; Cederholm A; Ogishi M; Arango-Franco CA; Béziat V; Lévy R; Migaud M; Rapaport F; Itan Y; Deenick EK; Cortese I; Lisco A; Boztug K; Abel L; Boisson-Dupuis S; Boisson B; Frosk P; Ma CS; Landegren N; Celmeli F; Casanova JL; Tangye SG; Puel A, 2024, 'Inherited human RelB deficiency impairs innate and adaptive immunity to infection', Proceedings of the National Academy of Sciences of the United States of America, 121,
    Journal articles | 2024
    Li MWY; Burnett L; Dai P; Avery DT; Noori T; Voskoboinik I; Shah PR; Tatian A; Tangye SG; Gray PE; Ma CS, 2024, 'Filaggrin-Associated Atopic Skin, Eye, Airways, and Gut Disease, Modifying the Presentation of X-Linked Reticular Pigmentary Disorder (XLPDR)', Journal of Clinical Immunology, 44,
    Journal articles | 2024
    Ma CS; Tangye SG, 2024, 'STAT3 gain of function: Too much of a good thing in the skin!', Journal of Experimental Medicine, 221,
    Journal articles | 2024
    Marchal A; Cirulli ET; Neveux I; Bellos E; Thwaites RS; Schiabor Barrett KM; Zhang Y; Nemes-Bokun I; Kalinova M; Catchpole A; Tangye SG; Spaan AN; Lack JB; Ghosn J; Burdet C; Gorochov G; Tubach F; Hausfater P; Abel L; Aiuti A; Al-Muhsen S; Al-Mulla F; Amara A; Anderson MS; Andreakos E; Arias AA; Arkin LM; Feldman HB; Bastard P; Belot A; Biggs CM; Bogunovic D; Bolze A; Bondarenko A; Borghesi A; Bousfiha AA; Brodin P; Bryceson Y; Butte MJ; Casanova JL; Casari G; Christodoulou J; Cobat A; Colobran R; Condino-Neto A; Constantinescu SN; Cooper MA; Dalgard CL; Desai M; Drolet BA; Duval X; El Baghdadi J; Eloy P; Espinosa-Padilla S; Fellay J; Flores C; Franco JL; Froidure A; Gregersen PK; Grimbacher B; Haerynck F; Hagin D; Halwani R; Hammarström L; Heath JR; Hsieh EWY; Husebye E; Imai K; Itan Y; Jouanguy E; Kaja E; Karamitros T; Kisand K; Ku CL; Lau YL; Ling Y; Lucas CL; Maniatis T; Mansouri D; Maródi L; Mentré F; Meyts I; Milner JD; Mironska K; Mogensen TH; Morio T; Ng LFP; Notarangelo LD; Novelli A; Novelli G; O'Farrelly C; Okada S; Okamoto K; Özçelik T; Pan-Hammarström Q; Pape JW; Perez de Diego R; Perez-Tur J; Perlin DS; Pesole G, 2024, 'Lack of association between classical HLA genes and asymptomatic SARS-CoV-2 infection', Human Genetics and Genomics Advances, 5,
    Journal articles | 2024
    Martin E; Winter S; Garcin C; Tanita K; Hoshino A; Lenoir C; Fournier B; Migaud M; Boutboul D; Simonin M; Fernandes A; Bastard P; Le Voyer T; Roupie AL; Ben Ahmed Y; Leruez-Ville M; Burgard M; Rao G; Ma CS; Masson C; Soudais C; Picard C; Bustamante J; Tangye SG; Cheikh N; Seppänen M; Puel A; Daly M; Casanova JL; Neven B; Fischer A; Latour S, 2024, 'Role of IL-27 in Epstein–Barr virus infection revealed by IL-27RA deficiency', Nature, 628, pp. 620 - 629,
    Journal articles | 2024
    Mina ED; Jackson KJL; Crawford AJI; Faulks ML; Pathmanandavel K; Acquarola N; O’Sullivan M; Kerre T; Naesens L; Claes K; Goodnow CC; Haerynck F; Kracker S; Meyts I; D’Orsogna LJ; Ma CS; Tangye SG, 2024, 'A Novel Heterozygous Variant in AICDA Impairs Ig Class Switching and Somatic Hypermutation in Human B Cells and is Associated with Autosomal Dominant HIGM2 Syndrome', Journal of Clinical Immunology, 44,
    Journal articles | 2024
    Momenilandi M; Lévy R; Sobrino S; Li J; Lagresle-Peyrou C; Esmaeilzadeh H; Fayand A; Le Floc'h C; Guérin A; Mina ED; Shearer D; Delmonte OM; Yatim A; Mulder K; Mancini M; Rinchai D; Denis A; Neehus AL; Balogh K; Brendle S; Rokni-Zadeh H; Changi-Ashtiani M; Seeleuthner Y; Deswarte C; Bessot B; Cremades C; Materna M; Cederholm A; Ogishi M; Philippot Q; Beganovic O; Ackermann M; Wuyts M; Khan T; Fouéré S; Herms F; Chanal J; Palterer B; Bruneau J; Molina TJ; Leclerc-Mercier S; Prétet JL; Youssefian L; Vahidnezhad H; Parvaneh N; Claeys KG; Schrijvers R; Luka M; Pérot P; Fourgeaud J; Nourrisson C; Poirier P; Jouanguy E; Boisson-Dupuis S; Bustamante J; Notarangelo LD; Christensen N; Landegren N; Abel L; Marr N; Six E; Langlais D; Waterboer T; Ginhoux F; Ma CS; Tangye SG; Meyts I; Lachmann N; Hu J; Shahrooei M; Bossuyt X; Casanova JL; Béziat V, 2024, 'FLT3L governs the development of partially overlapping hematopoietic lineages in humans and mice', Cell, 187, pp. 2817 - 2837.e31,
    Journal articles | 2024
    Noma K; Tsumura M; Nguyen T; Asano T; Sakura F; Tamaura M; Imanaka Y; Mizoguchi Y; Karakawa S; Hayakawa S; Shoji T; Hosokawa J; Izawa K; Ling Y; Casanova JL; Puel A; Tangye SG; Ma CS; Ohara O; Okada S, 2024, 'Isolated Chronic Mucocutaneous Candidiasis due to a Novel Duplication Variant of IL17RC', Journal of Clinical Immunology, 44,
    Journal articles | 2024
    Pathmanandavel K; Jackson K; Le S; Alves M; Foley E; Tangye S; Ma C; Deenick E; Tong W; Carr A; Breit S; Sewell W; Kane A, 2024, 'Mucosal-associated invariant T (MAIT) cells exhibit restricted T cell receptor β constant region usage, obfuscating assessment of T cell clonality', Pathology, 56, pp. S114 - S114,
    Journal articles | 2024
    Pathmanandavel K; Tangye SG; Ma CS, 2024, 'Flow Cytometric Identification of Human IgE+ B Lineage Subsets', , 2826, pp. 189 - 199,
    Journal articles | 2024
    Tangye S, 2024, '123 Helper T cell immunity in humans with inherited CD4 deficiency', Clinical Immunology, 262, pp. 110065 - 110065,
    Journal articles | 2024
    Tangye SG; Mackie J; Pathmanandavel K; Ma CS, 2024, 'The trajectory of human B-cell function, immune deficiency, and allergy revealed by inborn errors of immunity', Immunological Reviews, 322, pp. 212 - 232,
    Journal articles | 2023
    Akerman A; Milogiannakis V; Jean T; Esneau C; Silva MR; Ison T; Fichter C; Lopez JA; Chandra D; Naing Z; Caguicla J; Li D; Walker G; Amatayakul-Chantler S; Roth N; Manni S; Hauser T; Barnes T; Condylios A; Yeang M; Wong M; Foster CSP; Sato K; Lee S; Song Y; Mao L; Sigmund A; Phu A; Vande More AM; Hunt S; Douglas M; Caterson I; Britton W; Sandgren K; Bull R; Lloyd A; Triccas J; Tangye S; Bartlett NW; Darley D; Matthews G; Stark DJ; Petoumenos K; Rawlinson WD; Murrell B; Brilot F; Cunningham AL; Kelleher AD; Aggarwal A; Turville SG, 2023, 'Emergence and antibody evasion of BQ, BA.2.75 and SARS-CoV-2 recombinant sub-lineages in the face of maturing antibody breadth at the population level', eBioMedicine, 90,
    Journal articles | 2023
    Bohlen J; Michelet M; Barzaghi F; Saettini F; Vendemini F; Catala A; Alsina L; Conti F; Consonni F; Learndini D; Masetti R; Muratore E; Baccelli F; Bagaric I; Vatovec T; Seyed F; Andre I; Buetow L; Delabesse E; Largeaud L; Ma C; Abel L; Sobrino S; Ogishi M; Bessot B; Rouillon C; Bole C; Seeleuthner Y; Voyer TL; Rinchai D; Rosain J; Zhang P; Chaldebas M; Neehus A-L; Erazo L; Janda Z; Soudee C; Lagrese C; Six E; Huang D; Tangye S; Beziat V; Gambineri E; Veltroni M; Erlacher M; Aiuti A; Pasquet M; Casanova J-L; Bustamante J, 2023, 'HOMOZYGOUS CBL MUTATION IN B LYMPHOCYTES AFTER CBL-DRIVEN JMML IMPAIRS B CELL MATURATION, FUNCTION AND ANTIBACTERIAL IMMUNITY', EJC Paediatric Oncology, 2, pp. 100040 - 100040,
    Journal articles | 2023
    Bucciol G; Abel L; Al-Muhsen S; Aiuti A; Al-Mulla F; Andreakos E; Antonio N; Arias AA; Trouillet-Assant S; Belot A; Biggs CM; Bousfiha AA; Bolze A; Borghesi A; Brodin P; Christodoulou J; Cobat A; Condino-Neto A; Constantinescu S; Dalgard CL; Espinosa-Padilla S; Fellay J; Flores C; Franco JL; Froidure A; Gorochov G; Haerynck F; Halwani R; Hsieh EWY; Itan Y; Kisand K; Lau YL; Mansouri D; Meyts I; Mogensen TH; Ng LFP; Notarangelo LD; Novelli G; Okada S; Ozcelik T; Perez de Diego R; Prando C; Pujol A; Quintana-Murci L; Renia L; Resnick I; Roussel L; Rodríguez-Gallego C; Sancho-Shimizu V; Shahrooei M; Soler-Palacín P; Spaan AN; Tancevski I; Tangye SG; Tayoun AA; Temel ŞG; Tiberghien P; Tur JP; Turvey SE; Uddin F; Uddin MJ; Vidigal M; Vinh DC; Zatz M; Okamoto K; Perlin DS; Pesole G; Thorball C; van de Beek D; Colobran R; Wauters J; Zhang SY; Zhang Q; Su HC; Casanova JL, 2023, 'Inherited and acquired errors of type I interferon immunity govern susceptibility to COVID-19 and multisystem inflammatory syndrome in children', Journal of Allergy and Clinical Immunology, 151, pp. 832 - 840,
    Journal articles | 2023
    Le Voyer T; Parent AV; Liu X; Cederholm A; Gervais A; Rosain J; Nguyen T; Perez Lorenzo M; Rackaityte E; Rinchai D; Zhang P; Bizien L; Hancioglu G; Ghillani-Dalbin P; Charuel JL; Philippot Q; Gueye MS; Maglorius Renkilaraj MRL; Ogishi M; Soudée C; Migaud M; Rozenberg F; Momenilandi M; Riller Q; Imberti L; Delmonte OM; Müller G; Keller B; Orrego J; Franco Gallego WA; Rubin T; Emiroglu M; Parvaneh N; Eriksson D; Aranda-Guillen M; Berrios DI; Vong L; Katelaris CH; Mustillo P; Raedler J; Bohlen J; Bengi Celik J; Astudillo C; Winter S; Boisson-Dupuis S; Oksenhendler E; Okada S; Caluseriu O; Ursini MV; Ballot E; Lafarge G; Freiberger T; Arango-Franco CA; Levy R; Aiuti A; Al-Muhsen S; Al-Mulla F; Andreakos E; Arias AA; Feldman HB; Bastard P; Bondarenko A; Borghesi A; Bousfiha AA; Brodin P; Bryceson Y; Casari G; Christodoulou J; Colobran R; Condino-Neto A; Fellay J; Flores C; Franco JL; Haerynck F; Halwani R; Hammarström L; Heath JR; Hsieh EWY; Itan Y; Kaja E; Kisand K; Ku CL; Ling Y; Lau YL; Mansouri D; Meyts I; Milner JD; Mogensen TH; Novelli A; Novelli G; Okamoto K; Ozcelik T; de Diego RP; Perez-Tur J; Perlin DS; Prando C; Pujol A; Quintana-Murci L; Renia L; Resnick I, 2023, 'Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency', Nature, 623, pp. 803 - 813,
    Journal articles | 2023
    Leiding JW; Vogel TP; Santarlas VGJ; Mhaskar R; Smith MR; Carisey A; Vargas-Hernández A; Silva-Carmona M; Heeg M; Rensing-Ehl A; Neven B; Hadjadj J; Hambleton S; Ronan Leahy T; Meesilpavikai K; Cunningham-Rundles C; Dutmer CM; Sharapova SO; Taskinen M; Chua I; Hague R; Klemann C; Kostyuchenko L; Morio T; Thatayatikom A; Ozen A; Scherbina A; Bauer CS; Flanagan SE; Gambineri E; Giovannini-Chami L; Heimall J; Sullivan KE; Allenspach E; Romberg N; Deane SG; Prince BT; Rose MJ; Bohnsack J; Mousallem T; Jesudas R; Santos Vilela MMD; O'Sullivan M; Pachlopnik Schmid J; Průhová Š; Klocperk A; Rees M; Su H; Bahna S; Baris S; Bartnikas LM; Chang Berger A; Briggs TA; Brothers S; Bundy V; Chan AY; Chandrakasan S; Christiansen M; Cole T; Cook MC; Desai MM; Fischer U; Fulcher DA; Gallo S; Gauthier A; Gennery AR; Gonçalo Marques J; Gottrand F; Grimbacher B; Grunebaum E; Haapaniemi E; Hämäläinen S; Heiskanen K; Heiskanen-Kosma T; Hoffman HM; Gonzalez-Granado LI; Guerrerio AL; Kainulainen L; Kumar A; Lawrence MG; Levin C; Martelius T; Neth O; Olbrich P; Palma A; Patel NC; Pozos T; Preece K; Lugo Reyes SO; Russell MA; Schejter Y; Seroogy C; Sinclair J; Skevofilax E; Suan D; Suez D; Szabolcs P; Velasco H; Warnatz K; Walkovich K, 2023, 'Monogenic early-onset lymphoproliferation and autoimmunity: Natural history of STAT3 gain-of-function syndrome', Journal of Allergy and Clinical Immunology, 151, pp. 1081 - 1095,
    Journal articles | 2023
    Ma CS; Tangye SG, 2023, 'Inborn errors of immunity: the Goldilocks effect—susceptibility to disease due to a little too much or a little too little', Clinical and Experimental Immunology, 212, pp. 93 - 95,
    Journal articles | 2023
    Mackie J; Ma CS; Tangye SG; Guerin A, 2023, 'The ups and downs of STAT3 function: too much, too little and human immune dysregulation', Clinical and Experimental Immunology, 212, pp. 107 - 116,
    Journal articles | 2023
    Matuozzo D; Talouarn E; Marchal A; Zhang P; Manry J; Seeleuthner Y; Zhang Y; Bolze A; Chaldebas M; Milisavljevic B; Gervais A; Bastard P; Asano T; Bizien L; Barzaghi F; Abolhassani H; Abou Tayoun A; Aiuti A; Alavi Darazam I; Allende LM; Alonso-Arias R; Arias AA; Aytekin G; Bergman P; Bondesan S; Bryceson YT; Bustos IG; Cabrera-Marante O; Carcel S; Carrera P; Casari G; Chaïbi K; Colobran R; Condino-Neto A; Covill LE; Delmonte OM; El Zein L; Flores C; Gregersen PK; Gut M; Haerynck F; Halwani R; Hancerli S; Hammarström L; Hatipoğlu N; Karbuz A; Keles S; Kyheng C; Leon-Lopez R; Franco JL; Mansouri D; Martinez-Picado J; Metin Akcan O; Migeotte I; Morange PE; Morelle G; Martin-Nalda A; Novelli G; Novelli A; Palabiyik F; Pan-Hammarström Q; de Diego RP; Planas-Serra L; Pleguezuelo DE; Prando C; Pujol A; Reyes LF; Rivière JG; Rodriguez-Gallego C; Rojas J; Rovere-Querini P; Schlüter A; Shahrooei M; Sobh A; Soler-Palacin P; Tandjaoui-Lambiotte Y; Tipu I; Tresoldi C; Troya J; van de Beek D; Zatz M; Zawadzki P; Al-Muhsen SZ; Alosaimi MF; Alsohime FM; Baris-Feldman H; Butte MJ; Constantinescu SN; Cooper MA; Dalgard CL; Fellay J; Heath JR; Lau YL; Lifton RP; Maniatis T; Mogensen TH; von Bernuth H; Lermine A; Vidaud M; Boland A, 2023, 'Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19', Genome Medicine, 15,
    Journal articles | 2023
    Nguyen T; Lau A; Bier J; Cooke KC; Lenthall H; Ruiz-Diaz S; Avery DT; Brigden H; Zahra D; Sewell WA; Droney L; Okada S; Asano T; Abolhassani H; Chavoshzadeh Z; Abraham RS; Rajapakse N; Klee EW; Church JA; Williams A; Wong M; Burkhart C; Uzel G; Croucher DR; James DE; Ma CS; Brink R; Tangye SG; Deenick EK, 2023, 'Human PIK3R1 mutations disrupt lymphocyte differentiation to cause activated PI3Kδ syndrome 2', The Journal of experimental medicine, 220,
    Journal articles | 2023
    Philippot Q; Fekkar A; Gervais A; Le Voyer T; Boers LS; Conil C; Bizien L; de Brabander J; Duitman JW; Romano A; Rosain J; Blaize M; Migaud M; Jeljeli M; Hammadi B; Desmons A; Marchal A; Nossent EJ; Saris A; De Vries H; Meijboom LJ; Blok SG; Schuurman AR; Reijnders TDY; Hugenholtz F; Vallejo JJG; Bontkes H; Vlaar APJ; Wiersinga J; Lutter R; van der Poll T; Bogaard HJ; Kullberg RFJ; Zhang S; Heunks LMA; Tuinman PR; Bonta PI; Abel L; Al-Muhsen S; Arias AA; Bogunovic D; Bolze A; Bousfiha AA; Mansouri D; Meyts I; de Diego RP; Sancho-Shimizu V; Spaan AN; Tangye SG; Zhang SY; Su HC; Mayaux J; Zhang Q; Jouanguy E; Borie R; Crestani B; Luyt CE; Adle-Biassette H; Sene D; Megarbane B; Cobat A; Bastard P; Bos LDJ; Casanova JL; Puel A, 2023, 'Autoantibodies Neutralizing Type I IFNs in the Bronchoalveolar Lavage of at Least 10% of Patients During Life-Threatening COVID-19 Pneumonia', Journal of Clinical Immunology, 43, pp. 1093 - 1103,
    Journal articles | 2023
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    Tangye SG; Abel L; Al-Muhsen S; Aiuti A; Al-Muhsen S; Al-Mulla F; Anderson MS; Andreakos E; Novelli A; Arias AA; Feldman HB; Belot A; Biggs CM; Bousfiha AA; Brodin P; Christodoulou J; Condino-Neto A; Dalgard CL; Espinosa-Padilla S; Fellay J; Flores C; Franco JL; Froidure A; Haerynck F; Halwani R; Hammarström L; Henrickson SE; Hsieh EWY; Itan Y; Karamitros T; Lau YL; Mansouri D; Meyts I; Mogensen TH; Morio T; Ng LFP; Notarangelo LD; Novelli G; Okada S; Ozcelik T; Pan-Hammarström Q; Perez de Diego R; Prando C; Pujol A; Renia L; Resnick I; Rodríguez-Gallego C; Sancho-Shimizu V; Seppänen MRJ; Shcherbina A; Snow AL; Soler-Palacín P; Spaan AN; Tancevski I; Tayoun AA; Temel SG; Turvey SE; Uddin MJ; Vinh DC; Zatz M; Okamoto K; Pelin DS; Pesole G; van de Beek D; Colobran R; Wauters J; Su HC; Casanova JL, 2023, 'Impact of SARS-CoV-2 infection and COVID-19 on patients with inborn errors of immunity', Journal of Allergy and Clinical Immunology, 151, pp. 818 - 831,
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    Tangye SG; Meyts I, 2023, 'DOCK11 and Immune Disease', New England Journal of Medicine, 389, pp. 563 - 567,
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    Tangye SG; Nguyen T; Deenick EK; Bryant VL; Ma CS, 2023, 'Inborn errors of human B cell development, differentiation, and function', Journal of Experimental Medicine, 220,
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    Tangye SG; Pathmanandavel K; Ma CS, 2023, 'Cytokine-mediated STAT-dependent pathways underpinning human B-cell differentiation and function', Current Opinion in Immunology, 81,
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    Tangye SG; Puel A, 2023, 'The Th17/IL-17 Axis and Host Defense Against Fungal Infections', Journal of Allergy and Clinical Immunology: In Practice, 11, pp. 1624 - 1634,
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    Tangye SG, 2023, 'Do multiple subsets of CD11c+ B cells exist? You (T)-Bet!', Journal of Allergy and Clinical Immunology, 152, pp. 607 - 609,
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    Tangye SG, 2023, 'For whom the b(C)ell tolls: Cxcl4 aids human autoimmunity', Journal of Experimental Medicine, 220,
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    Bier J; Brink R; Tangye S; Deenick EK, 2022, 'T cell extrinsic mechanics explaining the T cell hyperactivation seen in Activated PI3K delta Syndrome', JOURNAL OF IMMUNOLOGY, 208,
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    Bousfiha A; Moundir A; Tangye SG; Picard C; Jeddane L; Al-Herz W; Rundles CC; Franco JL; Holland SM; Klein C; Morio T; Oksenhendler E; Puel A; Puck J; Seppänen MRJ; Somech R; Su HC; Sullivan KE; Torgerson TR; Meyts I, 2022, 'The 2022 Update of IUIS Phenotypical Classification for Human Inborn Errors of Immunity', Journal of Clinical Immunology, 42, pp. 1508 - 1520,
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    Deenick E; Lau A; Nguyen T; Bier J; Brink R; Tangye S, 2022, 'Analysing the cellular mechanisms underlying activated PI3K delta Syndrome (APDS) reveals differences between APDS1 and APDS2', JOURNAL OF IMMUNOLOGY, 208,
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    Gray PE; Bartlett AW; Tangye SG, 2022, 'Severe COVID-19 represents an undiagnosed primary immunodeficiency in a high proportion of infected individuals', Clinical and Translational Immunology, 11, pp. e1365,
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    Kermode W; De Santis D; Truong L; Della Mina E; Salman S; Thompson G; Nolan D; Loh R; Mallon D; Mclean-Tooke A; John M; Tangye SG; O'Sullivan M; D'Orsogna LJ, 2022, 'A Novel Targeted Amplicon Next-Generation Sequencing Gene Panel for the Diagnosis of Common Variable Immunodeficiency Has a High Diagnostic Yield: Results from the Perth CVID Cohort Study', Journal of Molecular Diagnostics, 24, pp. 586 - 599,
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    Masle-Farquhar E; Jackson KJL; Peters TJ; Al-Eryani G; Singh M; Payne KJ; Rao G; Avery DT; Apps G; Kingham J; Jara CJ; Skvortsova K; Swarbrick A; Ma CS; Suan D; Uzel G; Chua I; Leiding JW; Heiskanen K; Preece K; Kainulainen L; O'Sullivan M; Cooper MA; Seppänen MRJ; Mustjoki S; Brothers S; Vogel TP; Brink R; Tangye SG; Reed JH; Goodnow CC, 2022, 'STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2Dhi CD8+ T cell dysregulation and accumulation', Immunity, 55, pp. 2386 - 2404.e8,
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    Mayr D; Shahin T; Shoeb M; Kuehn HS; Hoeger B; Giuliani S; Gawriyski L; Yüce Petronczki Ö; Hadjadj J; Köstel Bal S; Zoghi S; Haimel M; Jimenez Heredia R; Boutboul D; Triebwasser M; Rialland-Battisti F; Tangye S; Fleisher T; Rezaei N; Romberg N; Latour S; Varjosalo M; Halbritter F; Rieux-Laucat F; Castanon I; Rosenzweig S; Boztug K, 2022, 'P1408: MONOALLELIC AND BIALLELIC GERMLINE MUTATIONS AFFECTING THE TRANSCRIPTION FACTOR HELIOS CAUSE PLEIOTROPIC DEFECTS OF IMMUNITY', HemaSphere, 6, pp. 1292 - 1293,
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    Mina ED; Tangye SG, 2022, 'Atypical Autosomal Recessive AID Deficiency—Yet Another Piece of the Hyper-IgM Puzzle', Journal of Clinical Immunology, 42, pp. 713 - 715,
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    Pelham SJ; Caldirola MS; Avery DT; Mackie J; Rao G; Gothe F; Peters TJ; Guerin A; Neumann D; Vokurkova D; Hwa V; Zhang W; Lyu SC; Chang I; Manohar M; Nadeau KC; Gaillard MI; Bezrodnik L; Iotova V; Zwirner NW; Gutierrez M; Al-Herz W; Goodnow CC; Vargas-Hernández A; Forbes Satter LR; Hambleton S; Deenick EK; Ma CS; Tangye SG, 2022, 'STAT5B restrains human B-cell differentiation to maintain humoral immune homeostasis', Journal of Allergy and Clinical Immunology, 150, pp. 931 - 946,
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    Shahin T; Mayr D; Shoeb MR; Kuehn HS; Hoeger B; Giuliani S; Gawriyski LM; Petronczki ÖY; Hadjadj J; Bal SK; Zoghi S; Haimel M; Heredia RJ; Boutboul D; Triebwasser MP; Rialland-Battisti F; Chalumeau NC; Quartier P; Tangye SG; Fleisher TA; Rezaei N; Romberg N; Latour S; Varjosalo M; Halbritter F; Rieux-Laucat F; Castanon I; Rosenzweig SD; Boztug K, 2022, 'Identification of germline monoallelic mutations in IKZF2 in patients with immune dysregulation', Blood Advances, 6, pp. 2444 - 2451,
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    Tangye SG; Al-Herz W; Bousfiha A; Cunningham-Rundles C; Franco JL; Holland SM; Klein C; Morio T; Oksenhendler E; Picard C; Puel A; Puck J; Seppänen MRJ; Somech R; Su HC; Sullivan KE; Torgerson TR; Meyts I, 2022, 'Human Inborn Errors of Immunity: 2022 Update on the Classification from the International Union of Immunological Societies Expert Committee', Journal of Clinical Immunology, 42, pp. 1473 - 1507,
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    Tangye SG; Burnett DL; Bull RA, 2022, 'Getting to the (germinal) center of humoral immune responses to SARS-CoV-2', Cell, 185, pp. 945 - 948,
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    Tangye SG; Gray PE; Pillay BA; Yap JY; Figgett WA; Reeves J; Kummerfeld SK; Stoddard J; Uzel G; Jing H; Su HC; Campbell DE; Sullivan A; Burnett L; Peake J; Ma CS, 2022, 'Hyper-IgE Syndrome due to an Elusive Novel Intronic Homozygous Variant in DOCK8', Journal of Clinical Immunology, 42, pp. 119 - 129,
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    Tangye SG; Warnatz K, 2022, '“Are you gonna go my way?”—Decisions at the Tfh-B cell interface', Immunity, 55, pp. 377 - 379,
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    Yang R; Avery DT; Jackson KJL; Ogishi M; Benhsaien I; Du L; Ye X; Han J; Rosain J; Peel JN; Alyanakian MA; Neven B; Winter S; Puel A; Boisson B; Payne KJ; Wong M; Russell AJ; Mizoguchi Y; Okada S; Uzel G; Goodnow CC; Latour S; Bakkouri JE; Bousfiha A; Preece K; Gray PE; Keller B; Warnatz K; Boisson-Dupuis S; Abel L; Pan-Hammarström Q; Bustamante J; Ma CS; Casanova JL; Tangye SG, 2022, 'Human T-bet governs the generation of a distinct subset of CD11chighCD21low B cells', Science Immunology, 7,
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    Asano T; Khourieh J; Zhang P; Rapaport F; Spaan AN; Li J; Lei WT; Pelham SJ; Hum D; Chrabieh M; Han JE; Guérin A; Mackie J; Gupta S; Saikia B; Baghdadi JEI; Fadil I; Bousfiha A; Habib T; Marr N; Ganeshanandan L; Peake J; Droney L; Williams A; Celmeli F; Hatipoglu N; Ozcelik T; Picard C; Abel L; Tangye SG; Boisson-Dupuis S; Zhang Q; Puel A; Béziat V; Casanova JL; Boisson B, 2021, 'Human stat3 variants underlie autosomal dominant hyper-igesyndromebynegativedominance', Journal of Experimental Medicine, 218,
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    Bigas A; Zanoni I; Hepworth MR; Eisenbarth SC; Masters SL; Kipnis J; Vinuesa CG; Good-Jacobson KL; Tangye SG; Yamazaki S; Hivroz C; Wojno ET; Shulman Z; Colonna M, 2021, 'JEM career launchpad', Journal of Experimental Medicine, 218,
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    Bucciol G; Tangye SG; Meyts I, 2021, 'Coronavirus disease 2019 in patients with inborn errors of immunity: Lessons learned', Current Opinion in Pediatrics, 33, pp. 648 - 656,
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    Bucciol G; Tousseyn T; Jansen K; Casteels I; Tangye SG; Breuer J; Brown JR; Wollants E; Van Ranst M; Moens L; Mekahli D; Meyts I, 2021, 'Hematopoietic Stem Cell Transplantation Cures Chronic Aichi Virus Infection in a Patient with X-linked Agammaglobulinemia', Journal of Clinical Immunology, 41, pp. 1403 - 1405,
    Journal articles | 2021
    Béziat V; Rapaport F; Hu J; Titeux M; Bonnet des Claustres M; Bourgey M; Griffin H; Bandet É; Ma CS; Sherkat R; Rokni-Zadeh H; Louis DM; Changi-Ashtiani M; Delmonte OM; Fukushima T; Habib T; Guennoun A; Khan T; Bender N; Rahman M; About F; Yang R; Rao G; Rouzaud C; Li J; Shearer D; Balogh K; Al Ali F; Ata M; Dabiri S; Momenilandi M; Nammour J; Alyanakian MA; Leruez-Ville M; Guenat D; Materna M; Marcot L; Vladikine N; Soret C; Vahidnezhad H; Youssefian L; Saeidian AH; Uitto J; Catherinot É; Navabi SS; Zarhrate M; Woodley DT; Jeljeli M; Abraham T; Belkaya S; Lorenzo L; Rosain J; Bayat M; Lanternier F; Lortholary O; Zakavi F; Gros P; Orth G; Abel L; Prétet JL; Fraitag S; Jouanguy E; Davis MM; Tangye SG; Notarangelo LD; Marr N; Waterboer T; Langlais D; Doorbar J; Hovnanian A; Christensen N; Bossuyt X; Shahrooei M; Casanova JL, 2021, 'Humans with inherited T cell CD28 deficiency are susceptible to skin papillomaviruses but are otherwise healthy', Cell, 184, pp. 3812 - 3828.e30,
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    Cagdas D; Mayr D; Baris S; Worley L; Langley DB; Metin A; Aytekin ES; Atan R; Kasap N; Bal SK; Dmytrus J; Heredia RJ; Karasu G; Torun SH; Toyran M; Karakoc-Aydiner E; Christ D; Kuskonmaz B; Uçkan-Çetinkaya D; Uner A; Oberndorfer F; Schiefer AI; Uzel G; Deenick EK; Keller B; Warnatz K; Neven B; Durandy A; Sanal O; Ma CS; Özen A; Stepensky P; Tezcan I; Boztug K; Tangye SG, 2021, 'Genomic Spectrum and Phenotypic Heterogeneity of Human IL-21 Receptor Deficiency', Journal of Clinical Immunology, 41, pp. 1272 - 1290,
    Journal articles | 2021
    Della Mina E; Guérin A; Tangye SG, 2021, 'Molecular requirements for human lymphopoiesis as defined by inborn errors of immunity', Stem Cells, 39, pp. 389 - 402,
    Journal articles | 2021
    Eisenbarth SC; Baumjohann D; Craft J; Fazilleau N; Ma CS; Tangye SG; Vinuesa CG; Linterman MA, 2021, 'CD4+ T cells that help B cells – a proposal for uniform nomenclature', Trends in Immunology, 42, pp. 658 - 669,
    Journal articles | 2021
    Hensen L; Illing PT; Bridie Clemens E; Nguyen THO; Koutsakos M; van de Sandt CE; Mifsud NA; Nguyen AT; Szeto C; Chua BY; Halim H; Rizzetto S; Luciani F; Loh L; Grant EJ; Saunders PM; Brooks AG; Rockman S; Kotsimbos TC; Cheng AC; Richards M; Westall GP; Wakim LM; Loudovaris T; Mannering SI; Elliott M; Tangye SG; Jackson DC; Flanagan KL; Rossjohn J; Gras S; Davies J; Miller A; Tong SYC; Purcell AW; Kedzierska K, 2021, 'CD8+ T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph', Nature Communications, 12,
    Journal articles | 2021
    Hewavisenti RV; Ferguson AL; Gasparini G; Ohashi T; Braun A; Watkins TS; Miles JJ; Elliott M; Sierro F; Feng CG; Britton WJ; Gebhardt T; Tangye S; Palendira U, 2021, 'Tissue-resident regulatory T cells accumulate at human barrier lymphoid organs', Immunology and Cell Biology, 99, pp. 894 - 906,
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    Keller B; Strohmeier V; Harder I; Unger S; Payne KJ; Andrieux G; Boerries M; Felixberger PT; Landry JJM; Nieters A; Rensing-Ehl A; Salzer U; Frede N; Usadel S; Elling R; Speckmann C; Hainmann I; Ralph E; Gilmour K; Wentink MWJ; van der Burg M; Kuehn HS; Rosenzweig SD; Kölsch U; von Bernuth H; Kaiser-Labusch P; Gothe F; Hambleton S; Vlagea AD; Garcia AG; Alsina L; Markelj G; Avcin T; Vasconcelos J; Guedes M; Ding JY; Ku CL; Shadur B; Avery DT; Venhoff N; Thiel J; Becker H; Erazo-Borrás L; Trujillo-Vargas CM; Franco JL; Fieschi C; Okada S; Gray PE; Uzel G; Casanova JL; Fliegauf M; Grimbacher B; Eibel H; Ehl S; Voll RE; Rizzi M; Stepensky P; Benes V; Ma CS; Bossen C; Tangye SG; Warnatz K, 2021, 'The expansion of human T-bethighCD21low B cells is T cell dependent', Science Immunology, 6,
    Journal articles | 2021
    Lévy R; Langlais D; Béziat V; Rapaport F; Rao G; Lazarov T; Bourgey M; Zhou YJ; Briand C; Moriya K; Ailal F; Avery DT; Markle J; Lim AI; Ogishi M; Yang R; Pelham S; Emam M; Migaud M; Deswarte C; Habib T; Saraiva LR; Moussa EA; Guennoun A; Boisson B; Belkaya S; Martinez-Barricarte R; Rosain J; Belkadi A; Breton S; Payne K; Benhsaien I; Plebani A; Lougaris V; Di Santo JP; Neven B; Abel L; Ma CS; Bousfiha AA; Marr N; Bustamante J; Liu K; Gros P; Geissmann F; Tangye SG; Casanova JL; Puel A, 2021, 'Inherited human c-Rel deficiency disrupts myeloid and lymphoid immunity to multiple infectious agents', Journal of Clinical Investigation, 131,
    Journal articles | 2021
    Meyts I; Bucciol G; Quinti I; Neven B; Fischer A; Seoane E; Lopez-Granados E; Gianelli C; Robles-Marhuenda A; Jeandel PY; Paillard C; Sankaran VG; Demirdag YY; Lougaris V; Aiuti A; Plebani A; Milito C; Dalm VA; Guevara-Hoyer K; Sánchez-Ramón S; Bezrodnik L; Barzaghi F; Gonzalez-Granado LI; Hayman GR; Uzel G; Mendonça LO; Agostini C; Spadaro G; Badolato R; Soresina A; Vermeulen F; Bosteels C; Lambrecht BN; Keller M; Mustillo PJ; Abraham RS; Gupta S; Ozen A; Karakoc-Aydiner E; Baris S; Freeman AF; Yamazaki-Nakashimada M; Scheffler-Mendoza S; Espinosa-Padilla S; Gennery AR; Jolles S; Espinosa Y; Poli MC; Fieschi C; Hauck F; Cunningham-Rundles C; Mahlaoui N; Warnatz K; Sullivan KE; Tangye SG, 2021, 'Coronavirus disease 2019 in patients with inborn errors of immunity: An international study', Journal of Allergy and Clinical Immunology, 147, pp. 520 - 531,
    Journal articles | 2021
    Nguyen T; Deenick EK; Tangye SG, 2021, 'Phosphatidylinositol 3-kinase signaling and immune regulation: insights into disease pathogenesis and clinical implications', Expert Review of Clinical Immunology, 17, pp. 905 - 914,
    Journal articles | 2021
    Ogishi M; Yang R; Aytekin C; Langlais D; Bourgey M; Khan T; Ali FA; Rahman M; Delmonte OM; Chrabieh M; Zhang P; Gruber C; Pelham SJ; Spaan AN; Rosain J; Lei WT; Drutman S; Hellmann MD; Callahan MK; Adamow M; Wong P; Wolchok JD; Rao G; Ma CS; Nakajima Y; Yaguchi T; Chamoto K; Williams SC; Emile JF; Rozenberg F; Glickman MS; Rapaport F; Kerner G; Allington G; Tezcan I; Cagdas D; Hosnut FO; Dogu F; Ikinciogullari A; Rao VK; Kainulainen L; Béziat V; Bustamante J; Vilarinho S; Lifton RP; Boisson B; Abel L; Bogunovic D; Marr N; Notarangelo LD; Tangye SG; Honjo T; Gros P; Boisson-Dupuis S; Casanova JL, 2021, 'Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child', Nature Medicine, 27, pp. 1646 - 1654,
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    Pillay BA; Fusaro M; Gray PE; Statham AL; Burnett L; Bezrodnik L; Kane A; Tong W; Abdo C; Winter S; Chevalier S; Levy R; Masson C; Schmitt Y; Bole C; Malphettes M; Macintyre E; de Villartay JP; Ziegler JB; Smart JM; Peake J; Aghamohammadi A; Hammarström L; Abolhassani H; Picard C; Fischer A; Latour S; Neven B; Tangye SG; Ma CS, 2021, 'Somatic reversion of pathogenic DOCK8 variants alters lymphocyte differentiation and function to effectively cure DOCK8 deficiency', Journal of Clinical Investigation, 131,
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    Sancho-Shimizu V; Brodin P; Cobat A; Biggs CM; Toubiana J; Lucas CL; Henrickson SE; Belot A; Tangye SG; Milner JD; Levin M; Abel L; Bogunovic D; Casanova JL; Zhang SY; Haddad E; Beland K; Pujol A; Schlüter A; Planas-Serra L; Aguilera-Albesa S; Valencia-Ramos J; Rodríguez-Palmero A; Gut M; Rivière JG; Colobran R; Soler-Palacin P; Rodriguez-Gallego C; de Diego RP; Flores C; Alsina L; Blazquez-Gamero D; Jordan I; Keles S; Emiroglu M; Akcan OM; Alkan G; Aytekin SE; Gul Y; Tüter Öz ŞK; Bozdemir SE; Bayhan GI; Yüksek SK; Parlakay AÖ; Gülhan B; Yahşi A; Kilic AO; Karbuz A; Erdeniz EH; Özkan EA; Orbak Z; Aydemir Ş; Celik JB; Kandemir B; Aytekin G; Kapakli H; Yarar V; Yosunkaya A; Vatansev H; Aytekin C; Torun SH; Nepesov S; Coskuner T; Sözeri B; Demirkol YK; Kasapcopur O; Yıldız M; Sevketoglu E; Hatipoğlu N; Özçelik T; Yesilbas O; Gayretli Aydin ZG; Sediva A; Klocperk A; Bloomfield M; Meyts I; Delafontaine S; Haerynck F; Hoste L; Shahrooei M; Marque L; Neves JF; Novelli G; Novelli A; Aiuti A; Casari G; Bousfiha AA; Almuhsen SZ; Sobh A; Gagro A; Bajolle F; Bonnet D; Lebon P; Lei W; Lee D; Seeleuthner Y; Zhang P; Maglorius M; Philippot Q; Pelham S, 2021, 'SARS-CoV-2-related MIS-C: A key to the viral and genetic causes of Kawasaki disease?', Journal of Experimental Medicine, 218,
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    Tangye SG; Al-Herz W; Bousfiha A; Cunningham-Rundles C; Franco JL; Holland SM; Klein C; Morio T; Oksenhendler E; Picard C; Puel A; Puck J; Seppänen MRJ; Somech R; Su HC; Sullivan KE; Torgerson TR; Meyts I, 2021, 'The Ever-Increasing Array of Novel Inborn Errors of Immunity: an Interim Update by the IUIS Committee', Journal of Clinical Immunology, 41, pp. 666 - 679,
    Journal articles | 2021
    Tangye SG; Bucciol G; Meyts I, 2021, 'Mechanisms underlying host defense and disease pathology in response to severe acute respiratory syndrome (SARS)-CoV2 infection: Insights from inborn errors of immunity', Current Opinion in Allergy and Clinical Immunology, 21, pp. 515 - 524,
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    Tangye SG; Ma CS, 2021, 'Molecular regulation and dysregulation of T follicular helper cells – learning from inborn errors of immunity', Current Opinion in Immunology, 72, pp. 249 - 261,
    Journal articles | 2021
    Yang R; Weisshaar M; Mele F; Benhsaien I; Dorgham K; Han J; Croft CA; Notarbartolo S; Rosain J; Bastard P; Puel A; Fleckenstein B; Glimcher LH; Di Santo JP; Ma CS; Gorochov G; Bousfiha A; Abel L; Tangye SG; Casanova JL; Bustamante J; Sallusto F, 2021, 'High Th2 cytokine levels and upper airway inflammation in human inherited T-bet deficiency', Journal of Experimental Medicine, 218,
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    Yap JY; Moens L; Lin MW; Kane A; Kelleher A; Toong C; Wu KHC; Sewell WA; Phan TG; Hollway GE; Enthoven K; Gray PE; Casas-Martin J; Wouters C; De Somer L; Hershfield M; Bucciol G; Delafontaine S; Ma CS; Tangye SG; Meyts I, 2021, 'Intrinsic Defects in B Cell Development and Differentiation, T Cell Exhaustion and Altered Unconventional T Cell Generation Characterize Human Adenosine Deaminase Type 2 Deficiency', Journal of Clinical Immunology, 41, pp. 1915 - 1935,
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    Journal articles | 2020
    Bedford JG; Heinlein M; Garnham AL; Nguyen THO; Loudovaris T; Ge C; Mannering SI; Elliott M; Tangye SG; Kedzierska K; Gray DHD; Heath WR; Wakim LM, 2020, 'Unresponsiveness to inhaled antigen is governed by conventional dendritic cells and overridden during infection by monocytes', Science Immunology, 5,
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    Bousfiha A; Jeddane L; Picard C; Al-Herz W; Ailal F; Chatila T; Cunningham-Rundles C; Etzioni A; Franco JL; Holland SM; Klein C; Morio T; Ochs HD; Oksenhendler E; Puck J; Torgerson TR; Casanova JL; Sullivan KE; Tangye SG, 2020, 'Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification', Journal of Clinical Immunology, 40, pp. 66 - 81,
    Journal articles | 2020
    Bucciol G; Pillay B; Casas-Martin J; Delafontaine S; Proesmans M; Lorent N; Coolen J; Tousseyn T; Bossuyt X; Ma CS; Schrijvers R; Tangye SG; Moens L; Meyts I, 2020, 'Systemic Inflammation and Myelofibrosis in a Patient with Takenouchi-Kosaki Syndrome due to CDC42 Tyr64Cys Mutation', Journal of Clinical Immunology, 40, pp. 567 - 570,
    Journal articles | 2020
    Béziat V; Tavernier SJ; Chen YH; Ma CS; Materna M; Laurence A; Staal J; Aschenbrenner D; Roels L; Worley L; Claes K; Gartner L; Kohn LA; De Bruyne M; Schmitz-Abe K; Charbonnier LM; Keles S; Nammour J; Vladikine N; Renkilaraj MRLM; Seeleuthner Y; Migaud M; Rosain J; Jeljeli M; Boisson B; Van Braeckel E; Rosenfeld JA; Dai H; Burrage LC; Murdock DR; Lambrecht BN; Avettand-Fenoel V; Vogel TP; Esther CR; Haskologlu S; Dogu F; Ciznar P; Boutboul D; Ouachée-Chardin M; Amourette J; Lebras MN; Gauvain C; Tcherakian C; Ikinciogullari A; Beyaert R; Abel L; Milner JD; Grimbacher B; Couderc LJ; Butte MJ; Freeman AF; Catherinot É; Fieschi C; Chatila TA; Tangye SG; Uhlig HH; Haerynck F; Casanova JL; Puel A, 2020, 'Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome', Journal of Experimental Medicine, 217,
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    Béziat V; Tavernier SJ; Chen YH; Ma CS; Materna M; Laurence A; Staal J; Aschenbrenner D; Roels L; Worley L; Claes K; Gartner L; Kohn LA; de Bruyne M; Schmitz-Abe K; Charbonnier LM; Keles S; Nammour J; Vladikine N; Renkilaraj MRLM; Seeleuthner Y; Migaud M; Rosain J; Jeljeli M; Boisson B; van Braeckel E; Rosenfeld JA; Dai H; Burrage LC; Murdock DR; Lambrecht BN; Avettand-Fenoel V; Vogel TP; Network UD; Esther CR; Haskologlu S; Dogu F; Ciznar P; Boutboul D; Ouachée-Chardin M; Amourette J; Lebras MN; Gauvain C; Tcherakian C; Ikinciogullari A; Beyaert R; Abel L; Milner JD; Grimbacher B; Couderc LJ; Butte MJ; Freeman AF; Catherinot É; Fieschi C; Chatila TA; Tangye SG; Uhlig HH; Haerynck F; Casanova JL; Puel A, 2020, 'Erratum: Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome (J. Exp. Med. (2020) 217:6 Doi:10.1084/jem.20191804)', Journal of Experimental Medicine, 217,
    Journal articles | 2020
    Casanova JL; Su HC; Abel L; Aiuti A; Almuhsen S; Arias AA; Bastard P; Biggs C; Bogunovic D; Boisson B; Boisson-Dupuis S; Bolze A; Bondarenko A; Bousfiha A; Brodin P; Bustamante J; Butte M; Casari G; Ciancanelli M; Cobat A; Condino-Neto A; Cooper M; Dalgard C; Espinosa S; Feldman H; Fellay J; Franco JL; Hagin D; Itan Y; Jouanguy E; Lucas C; Mansouri D; Meyts I; Milner J; Mogensen T; Morio T; Ng L; Notarangelo LD; Okada S; Ozcelik T; Palacín PS; Planas A; Prando C; Puel A; Pujol A; Redin C; Renia L; Rodriguez Gallego JC; Quintana-Murci L; Sancho-Shimizu V; Sankaran V; Seppänen MRJ; Shahrooei M; Snow A; Spaan A; Tangye S; Tur JP; Turvey S; Vinh DC; von Bernuth H; Wang X; Zawadzki P; Zhang Q; Zhang S, 2020, 'A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection', Cell, 181, pp. 1194 - 1199,
    Journal articles | 2020
    Fagbemi A; Newman WG; Tangye SG; Hughes SM; Arkwright PD; Cheesman E, 2020, 'Refractory very early-onset inflammatory bowel disease associated with cytosolic isoleucyl-tRNA synthetase deficiency: A case report', World Journal of Gastroenterology, 26, pp. 1841 - 1846,
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    French MA; Tangye SG, 2020, 'The next generation of diagnostic tests for primary immunodeficiency disorders', Journal of Infectious Diseases, 221, pp. 1232 - 1234,
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    Ghosh S; Bal SK; Edwards ESJ; Pillay B; Heredia RJ; Cipe FE; Rao G; Salzer E; Zoghi S; Abolhassani H; Momen T; Gostick E; Price DA; Zhang Y; Oler AJ; Gonzaga-Jauregui C; Erman B; Metin A; Ilhan I; Haskologlu S; Islamoglu C; Baskin K; Ceylaner S; Yilmaz E; Unal E; Karakukcu M; Berghuis D; Cole T; Gupta AK; Hauck F; Kogler H; Hoepelman AIM; Baris S; Karakoc-Aydiner E; Ozen A; Kager L; Holzinger D; Paulussen M; Krüger R; Meisel R; Oommen PT; Morris E; Neven B; Worth A; van Montfrans J; Fraaij PLA; Choo S; Dogu F; Graham Davies E; Burns S; Dückers G; Becker RP; von Bernuth H; Latour S; Faraci M; Gattorno M; Su HC; Pan-Hammarström Q; Hammarström L; Lenardo MJ; Ma CS; Niehues T; Aghamohammadi A; Rezaei N; Ikinciogullari A; Tangye SG; Lankester AC; Boztug K, 2020, 'Extended clinical and immunological phenotype and transplant outcome in CD27 and CD70 deficiency', Blood, 136, pp. 2638 - 2655,
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    Jouanguy E; Béziat V; Mogensen TH; Casanova JL; Tangye SG; Zhang SY, 2020, 'Human inborn errors of immunity to herpes viruses', Current Opinion in Immunology, 62, pp. 106 - 122,
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    Klinken EM; Gray PE; Pillay B; Worley L; Edwards ESJ; Payne K; Bennetts B; Hung D; Wood BA; Chan JJ; Marshall GM; Mitchell R; Uzel G; Ma CS; Tangye SG; McLean-Tooke A, 2020, 'Diversity of XMEN Disease: Description of 2 Novel Variants and Analysis of the Lymphocyte Phenotype', Journal of Clinical Immunology, 40, pp. 299 - 309,
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    Kong XF; Worley L; Rinchai D; Bondet V; Jithesh PV; Goulet M; Nonnotte E; Rebillat AS; Conte M; Mircher C; Gürtler N; Liu L; Migaud M; Elanbari M; Habib T; Ma CS; Bustamante J; Abel L; Ravel A; Lyonnet S; Munnich A; Duffy D; Chaussabel D; Casanova JL; Tangye SG; Boisson-Dupuis S; Puel A, 2020, 'Three Copies of Four Interferon Receptor Genes Underlie a Mild Type I Interferonopathy in Down Syndrome', Journal of Clinical Immunology, 40, pp. 807 - 819,
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    Lau A; Avery DT; Jackson K; Lenthall H; Volpi S; Brigden H; Russell AJ; Bier J; Reed JH; Smart JM; Cole T; Choo S; Gray PE; Berglund LJ; Hsu P; Wong M; O'Sullivan M; Boztug K; Meyts I; Uzel G; Notarangelo LD; Brink R; Goodnow CC; Tangye SG; Deenick EK, 2020, 'Activated PI3Kd breaches multiple B cell tolerance checkpoints and causes autoantibody production', Journal of Experimental Medicine, 217,
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    Lucas CL; Tangye SG, 2020, 'Editorial: Human Disorders of PI3K Biology', Frontiers in Immunology, 11,
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    Masle-Farquhar E; Payne K; Singh M; Rao G; Al-Eryani G; Jara C; Jackson K; Brink RA; Tangye S; Reed J; Goodnow CC, 2020, 'The effects of germline STAT3-activating mutations from autoimmunity and lymphoid malignancy on mouse and human T cells', The Journal of Immunology, 204, pp. 142.35 - 142.35,
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    Phan TG; Gray PE; Wong M; Macintosh R; Burnett L; Tangye SG, 2020, 'The Clinical Immunogenomics Research Consortium Australasia (CIRCA): a Distributed Network Model for Genomic Healthcare Delivery', Journal of Clinical Immunology, 40, pp. 763 - 766,
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    Tangye SG; Al-Herz W; Bousfiha A; Chatila T; Cunningham-Rundles C; Etzioni A; Franco JL; Holland SM; Klein C; Morio T; Ochs HD; Oksenhendler E; Picard C; Puck J; Torgerson TR; Casanova JL; Sullivan KE, 2020, 'Correction to: Human Inborn Errors of Immunity: 2019 Update on the Classification from the International Union of Immunological Societies Expert Committee (Journal of Clinical Immunology, (2020), 40, 1, (24-64), 10.1007/s10875-019-00737-x)', Journal of Clinical Immunology, 40, pp. 65,
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    Tangye SG; Al-Herz W; Bousfiha A; Chatila T; Cunningham-Rundles C; Etzioni A; Franco JL; Holland SM; Klein C; Morio T; Ochs HD; Oksenhendler E; Picard C; Puck J; Torgerson TR; Casanova JL; Sullivan KE, 2020, 'Human Inborn Errors of Immunity: 2019 Update on the Classification from the International Union of Immunological Societies Expert Committee', Journal of Clinical Immunology, 40, pp. 24 - 64,
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    Tangye SG; Latour S, 2020, 'Primary immunodeficiencies reveal the molecular requirements for effective host defense against EBV infection', Blood, 135, pp. 644 - 655,
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    Tangye SG; Ma CS, 2020, 'Regulation of the germinal center and humoral immunity by interleukin-21', Journal of Experimental Medicine, 217,
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    Tangye SG, 2020, 'Genetic susceptibility to EBV infection: insights from inborn errors of immunity', Human Genetics, 139, pp. 885 - 901,
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    Tangye SG, 2020, 'It's that time of year—APRIL promotes humoral immunity in humans', Journal of Allergy and Clinical Immunology, 146, pp. 1013 - 1015,
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    Yang R; Mele F; Worley L; Langlais D; Rosain J; Benhsaien I; Elarabi H; Croft CA; Doisne JM; Zhang P; Weisshaar M; Jarrossay D; Latorre D; Shen Y; Han J; Ogishi M; Gruber C; Markle J; Al Ali F; Rahman M; Khan T; Seeleuthner Y; Kerner G; Husquin LT; Maclsaac JL; Jeljeli M; Errami A; Ailal F; Kobor MS; Oleaga-Quintas C; Roynard M; Bourgey M; El Baghdadi J; Boisson-Dupuis S; Puel A; Batteux F; Rozenberg F; Marr N; Pan-Hammarström Q; Bogunovic D; Quintana-Murci L; Carroll T; Ma CS; Abel L; Bousfiha A; Di Santo JP; Glimcher LH; Gros P; Tangye SG; Sallusto F; Bustamante J; Casanova JL, 2020, 'Human T-bet Governs Innate and Innate-like Adaptive IFN-γ Immunity against Mycobacteria', Cell, 183, pp. 1826 - 1847.e31,
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    Yap JY; Gloss B; Batten M; Hsu P; Berglund L; Cai F; Dai P; Parker A; Qiu M; Miley W; Roshan R; Marshall V; Whitby D; Wegman E; Garsia R; Wu KHC; Kirk E; Polizzotto M; Deenick EK; Tangye SG; Ma CS; CIRCA ; Phan TG, 2020, 'Everolimus-Induced Remission of Classic Kaposi’s Sarcoma Secondary to Cryptic Splicing Mediated CTLA4 Haploinsufficiency', Journal of Clinical Immunology, 40, pp. 774 - 779,
    Journal articles | 2020
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    Ma CS, 2016, 'Human T Follicular Helper Cells in Primary Immunodeficiency: Quality Just as Important as Quantity', Journal of Clinical Immunology, 36, pp. 40 - 47,
    Journal articles | 2016
    Meli AP; Fontés G; Avery DT; Leddon SA; Tam M; Elliot M; Ballesteros-Tato A; Miller J; Stevenson MM; Fowell DJ; Tangye SG; King IL, 2016, 'The Integrin LFA-1 Controls T Follicular Helper Cell Generation and Maintenance', Immunity, 45, pp. 831 - 846,
    Journal articles | 2016
    Moens L; Kane A; Tangye SG, 2016, 'Naïve and memory B cells exhibit distinct biochemical responses following BCR engagement', Immunology and Cell Biology, 94, pp. 774 - 786,
    Journal articles | 2016
    Pelham SJ; Lenthall HC; Deenick EK; Tangye SG, 2016, 'Elucidating the effects of disease-causing mutations on STAT3 function in autosomal-dominant hyper-IgE syndrome', Journal of Allergy and Clinical Immunology, 138, pp. 1210 - 1213.e5,
    Journal articles | 2016
    Wang Y; Ma CS; Ling Y; Bousfiha A; Camcioglu Y; Jacquot S; Payne K; Crestani E; Roncagalli R; Belkadi A; Kerner G; Lorenzo L; Deswarte C; Chrabieh M; Patin E; Vincent QB; Müller-Fleckenstein I; Fleckenstein B; Ailal F; Quintana-Murci L; Fraitag S; Alyanakian MA; Leruez-Ville M; Picard C; Puel A; Bustamante J; Boisson-Dupuis S; Malissen M; Malissen B; Abel L; Hovnanian A; Notarangelo LD; Jouanguy E; Tangye SG; Béziat V; Casanova JL, 2016, 'Dual T cell- and B cell-intrinsic deficiency in humans with biallelic RLT PR mutations', Journal of Experimental Medicine, 213, pp. 2413 - 2435,
    Journal articles | 2016
    Woon HG; Braun A; Li J; Smith C; Edwards J; Sierro F; Feng CG; Khanna R; Elliot M; Bell A; Hislop AD; Tangye SG; Rickinson AB; Gebhardt T; Britton WJ; Palendira U, 2016, 'Compartmentalization of Total and Virus-Specific Tissue-Resident Memory CD8+ T Cells in Human Lymphoid Organs', PLoS Pathogens, 12,
    Journal articles | 2016
    vijayan D; redzwan M; avery DT; wirasinha RC; brink R; walters G; adelstein S; kobayashi M; gray P; elliott M; king C; vinuesa C; ghilardi N; ma CS; Tangye SG; batten M, 2016, 'IL-27 Directly Enhances Germinal Center B Cell Activity and Potentiates Lupus in Sanroque Mice', Journal of Immunology, 197, pp. 3008 - 3017,
    Journal articles | 2015
    Butt D; Chan TD; Bourne K; Hermes JR; Nguyen A; Statham A; O'Reilly LA; Strasser A; Price S; Schofield P; Christ D; Basten A; Ma CS; Tangye SG; Phan TG; Rao VK; Brink R, 2015, 'FAS Inactivation Releases Unconventional Germinal Center B Cells that Escape Antigen Control and Drive IgE and Autoantibody Production', Immunity, 42, pp. 890 - 902,
    Journal articles | 2015
    Gray PE; O’Brien TA; Wagle M; Tangye SG; Palendira U; Roscioli T; Choo S; Sutton R; Ziegler JB; Frith K, 2015, 'Cerebral Vasculitis in X-linked Lymphoproliferative Disease Cured by Matched Unrelated Cord Blood Transplant', Journal of Clinical Immunology, 35, pp. 604 - 609,
    Journal articles | 2015
    Kreins AY; Ciancanelli MJ; Okada S; Kong XF; Ramírez-Alejo N; Kilic SS; El Baghdadi J; Nonoyama S; Mahdaviani SA; Ailal F; Bousfiha A; Mansouri D; Nievas E; Ma CS; Rao G; Bernasconi A; Kuehn HS; Niemela J; Stoddard J; Deveau P; Cobat A; Azbaoui SE; Sabri A; Lim CK; Sundin M; Avery DT; Halwani R; Grant AV; Boisson B; Bogunovic D; Itan Y; Moncada-Velez M; Martinez-Barricarte R; Migaud M; Deswarte C; Alsina L; Kotlarz D; Klein C; Muller-Fleckenstein I; Fleckenstein B; Cormier-Daire V; Rose-John S; Picard C; Hammarstrom L; Puel A; Al-Muhsen S; Abel L; Chaussabel D; Rosenzweig SD; Minegishi Y; Tangye SG; Bustamante J; Casanova JL; Boisson-Dupuis S, 2015, 'Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome', Journal of Experimental Medicine, 212, pp. 1641 - 1662,
    Journal articles | 2015
    Ma CS; Wong N; Rao G; Avery DT; Torpy J; Hambridge T; Bustamante J; Okada S; Stoddard JL; Deenick EK; Pelham SJ; Payne K; Boisson-Dupuis S; Puel A; Kobayashi M; Arkwright PD; Kilic SS; El Baghdadi J; Nonoyama S; Minegishi Y; Mahdaviani SA; Mansouri D; Bousfiha A; Blincoe AK; French MA; Hsu P; Campbell DE; Stormon MO; Wong M; Adelstein S; Smart JM; Fulcher DA; Cook MC; Phan TG; Stepensky P; Boztug K; Kansu A; Ikincioʇullari A; Baumann U; Beier R; Roscioli T; Ziegler JB; Gray P; Picard C; Grimbacher B; Warnatz K; Holland SM; Casanova JL; Uzel G; Tangye SG, 2015, 'Monogenic mutations differentially affect the quantity and quality of T follicular helper cells in patients with human primary immunodeficiencies', Journal of Allergy and Clinical Immunology, 136, pp. 993 - 1006.e1,
    Journal articles | 2015
    Okada S; Markle JG; Deenick EK; Mele F; Averbuch D; Lagos M; Alzahrani M; Al-Muhsen S; Halwani R; Ma CS; Wong N; Soudais C; Henderson LA; Marzouqa H; Shamma J; Gonzalez M; Martinez-Barricarte R; Okada C; Avery DT; Latorre D; Deswarte C; Jabot-Hanin F; Torrado E; Fountain J; Belkadi A; Itan Y; Boisson B; Migaud M; Lindestam Arlehamn CS; Sette A; Breton S; Cluskey J; Rossjohn J; De Villartay JP; Moshous D; Hambleton S; Latour S; Arkwright PD; Picard C; Lantz O; Engelhard D; Kobayashi M; Abel L; Cooper AM; Notarangelo LD; Boisson-Dupuis S; Puel A; Sallusto F; Bustamante J; Tangye SG; Casanova JL, 2015, 'Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations', Science, 349, pp. 606 - 613,
    Journal articles | 2015
    Suan D; Nguyen A; Moran I; Bourne K; Hermes JR; Arshi M; Hampton HR; Tomura M; Miwa Y; Kelleher AD; Kaplan W; Deenick EK; Tangye SG; Brink R; Chtanova T; Phan TG, 2015, 'T Follicular Helper Cells Have Distinct Modes of Migration and Molecular Signatures in Naive and Memory Immune Responses', Immunity, 42, pp. 704 - 718,
    Journal articles | 2015
    Tangye SG; Brink R; Goodnow CC; Phan TG, 2015, 'SnapShot: Interactions between B Cells and T Cells', Cell, 162, pp. 926 - 926.e1,
    Journal articles | 2015
    Tangye SG, 2015, 'Advances in IL-21 biology-enhancing our understanding of human disease', Current Opinion in Immunology, 34, pp. 107 - 115,
    Journal articles | 2015
    Tangye SG, 2015, 'Thucydides and longer-lived plasma cells', Blood, 125, pp. 1684 - 1685,
    Journal articles | 2015
    Wilson RP; Ives ML; Rao G; Lau A; Payne K; Kobayashi M; Arkwright PD; Peake J; Wong M; Adelstein S; Smart JM; French MA; Fulcher DA; Picard C; Bustamante J; Boisson-Dupuis S; Gray P; Stepensky P; Warnatz K; Freeman AF; Rossjohn J; McCluskey J; Holland SM; Casanova JL; Uzel G; Ma CS; Tangye SG; Deenick EK, 2015, 'STAT3 is a critical cell-intrinsic regulator of human unconventional T cell numbers and function', Journal of Experimental Medicine, 212, pp. 855 - 864,
    Journal articles | 2014
    Hutchinson AT; Jones DR; McCauley Winter P; Tangye SG; Raison RL, 2014, 'Cell membrane associated free kappa light chains are found on a subset of tonsil and in vitro-derived plasmablasts', Human Immunology,
    Journal articles | 2014
    Hutchinson AT; Jones DR; McCauley Winter P; Tangye SG; Raison RL, 2014, 'Cell membrane associated free kappa light chains are found on a subset of tonsil and in vitro-derived plasmablasts', Human Immunology, 75, pp. 986 - 990,
    Journal articles | 2014
    Kane A; Deenick EK; Ma CS; Cook MC; Uzel G; Tangye SG, 2014, 'STAT3 is a central regulator of lymphocyte differentiation and function', Current Opinion in Immunology, 28, pp. 49 - 57,
    Journal articles | 2014
    Koganti S; Hui-Yuen J; McAllister S; Gardner B; Grasser F; Palendira U; Tangye SG; Freeman AF; Bhaduri-McIntosh S, 2014, 'STAT3 interrupts ATR-Chk1 signaling to allow oncovirus-mediated cell proliferation', Proceedings of the National Academy of Sciences of the United States of America, 111, pp. 4946 - 4951,
    Journal articles | 2014
    Kuehn HS; Ouyang W; Lo B; Deenick EK; Niemela JE; Avery DT; Schickel JN; Tran DQ; Stoddard J; Zhang Y; Frucht DM; Dumitriu B; Scheinberg P; Folio LR; Frein CA; Price S; Koh C; Heller T; Seroogy CM; Huttenlocher A; Rao VK; Su HC; Kleiner D; Notarangelo LD; Rampertaap Y; Olivier KN; McElwee J; Hughes J; Pittaluga S; Oliveira JB; Meffre E; Fleisher TA; Holland SM; Lenardo MJ; Tangye SG; Uzel G, 2014, 'Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4', Science, 345, pp. 1623 - 1627,
    Journal articles | 2014
    Lucas CL; Kuehn HS; Zhao F; Niemela JE; Deenick EK; Palendira U; Avery DT; Moens L; Cannons JL; Biancalana M; Stoddard J; Ouyang W; Frucht DM; Rao VK; Atkinson TP; Agharahimi A; Hussey AA; Folio LR; Olivier KN; Fleisher TA; Pittaluga S; Holland SM; Cohen JI; Oliveira JB; Tangye SG; Schwartzberg PL; Lenardo MJ; Uzel G, 2014, 'Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency', Nature Immunology, 15, pp. 88 - 97,
    Journal articles | 2014
    Ma CS; Uzel G; Tangye SG, 2014, 'Human T follicular helper cells in primary immunodeficiencies', Current Opinion in Pediatrics, 26, pp. 720 - 726,
    Journal articles | 2014
    Menard L; Cantaert T; Chamberlain N; Tangye SG; Riminton S; Church JA; Klion A; Cunningham-Rundles C; Nichols KE; Meffre E, 2014, 'Signaling lymphocytic activation molecule (SLAM)/SLAM-associated protein pathway regulates human B-cell tolerance', Journal of Allergy and Clinical Immunology, 133, pp. 1149 - 1161,
    Journal articles | 2014
    Moens L; Tangye SG, 2014, 'Cytokine-mediated regulation of plasma cell generation: IL-21 takes center stage', Frontiers in Immunology, 5,
    Journal articles | 2014
    Reynaud CA; Tangye S, 2014, 'Editorial overview: Lymphocyte activation and effector functions', Current Opinion in Immunology, 28, pp. v - vii,
    Journal articles | 2014
    Reynaud CA; Tangye S, 2014, 'Editorial overview: Lymphocyte activation and effector functions.', Current opinion in immunology, 28
    Journal articles | 2014
    Tangye SG, 2014, 'T cells require DOCK8 for flexibility and function', Journal of Experimental Medicine, 211, pp. 2482 - 2483,
    Journal articles | 2014
    Tangye SG, 2014, 'The right ''Job'' for STAT3 mutant mice!', Blood, 123, pp. 2907 - 2909,
    Journal articles | 2014
    Tangye SG, 2014, 'XLP: Clinical Features and Molecular Etiology due to Mutations in SH2D1A Encoding SAP', Journal of Clinical Immunology,
    Journal articles | 2014
    Tangye SG, 2014, 'XLP: Clinical Features and Molecular Etiology due to Mutations in SH2D1A Encoding SAP', Journal of Clinical Immunology, 34, pp. 772 - 779,
    Journal articles | 2013
    Agrawal S; Smith SABC; Tangye SG; Sewell WA, 2013, 'Transitional B cell subsets in human bone marrow', Clinical and Experimental Immunology, 174, pp. 53 - 59,
    Journal articles | 2013
    Berglund LJ; Avery DT; Ma CS; Moens L; Deenick EK; Bustamante J; Boisson-Dupuis S; Wong M; Adelstein S; Arkwright PD; Bacchetta R; Bezrodnik L; Dadi H; Roifman CM; Fulcher DA; Ziegler JB; Smart JM; Kobayashi M; Picard C; Durandy A; Cook MC; Casanova JL; Uzel G; Tangye SG, 2013, 'IL-21 signalling via STAT3 primes human näive B cells to respond to IL-2 to enhance their differentiation into plasmablasts', Blood, 122, pp. 3940 - 3950,
    Journal articles | 2013
    Boisson B; Wang YD; Bosompem A; Ma CS; Lim A; Kochetkov T; Tangye SG; Casanova JL; Conley ME, 2013, 'A recurrent dominant negative E47 mutation causes agammaglobulinemia and BCR- B cells', Journal of Clinical Investigation, 123, pp. 4781 - 4785,
    Journal articles | 2013
    Byun M; Ma Cindy S. CS; Akçay A; Pedergnana V; Palendira U; Myoung J; Avery DT; Liu Y; Abhyankar A; Lorenzo L; Schmidt M; Lim HK; Cassar O; Migaud M; Rozenberg F; Canpolat N; Aydogan G; Fleckenstein B; Bustamante J; Picard C; Gessain A; Jouanguy E; Cesarman E; Olivier M; Gros P; Abel L; Croft M; Tangye SG; Casanova JL, 2013, 'Inherited human OX40 deficiency underlying classic kaposi sarcoma of childhood', Journal of Experimental Medicine, 210, pp. 1743 - 1759,
    Journal articles | 2013
    Crawford G; Enders A; Gileadi U; Stankovic S; Zhang Q; Lambe T; Crockford TL; Lockstone HE; Freeman A; Arkwright PD; Smart JM; Ma CS; Tangye SG; Goodnow CC; Cerundolo V; Godfrey DI; Su HC; Randall KL; Cornall RJ, 2013, 'DOCK8 is critical for the survival and function of NKT cells', Blood, 122, pp. 2052 - 2061,
    Journal articles | 2013
    Deenick EK; Avery DT; Chan A; Berglund LJ; Ives ML; Moens L; Stoddard JL; Bustamante J; Boisson-Dupuis S; Tsumura M; Kobayashi M; Arkwright PD; Averbuch D; Engelhard D; Roesler J; Peake J; Wong M; Adelstein S; Choo S; Smart JM; French MA; Fulcher DA; Cook MC; Picard C; Durandy A; Klein C; Holland SM; Uzel G; Casanova JL; Ma CS; Tangye SG, 2013, 'Naive and memory human B cells have distinct requirements for STAT3 activation to differentiate into antibody-secreting plasma cells', Journal of Experimental Medicine, 210, pp. 2739 - 2753,
    Journal articles | 2013
    He J; Tsai LM; Leong YA; Hu X; Ma CS; Chevalier N; Sun X; Vandenberg K; Rockman S; Ding Y; Zhu L; Wei W; Wang C; Karnowski A; Belz GT; Ghali JR; Cook MC; Riminton DS; Veillette A; Schwartzberg PL; Mackay F; Brink R; Tangye SG; Vinuesa CG; Mackay CR; Li Z; Yu D, 2013, 'Circulating precursor CCR7loPD-1hi CXCR5+ CD4+ T cells indicate tfh cell activity and promote antibody responses upon antigen reexposure', Immunity, 39, pp. 770 - 781,
    Journal articles | 2013
    Hill ER; Kogantil S; Zhi J; Megyola C; Freeman AF; Palendira U; Tangye SG; Farrell PJ; Bhaduri-McIntosh S, 2013, 'Signal transducer and activator of transcription 3 limits epstein-barr virus lytic activation in B lymphocytes', Journal of Virology, 87, pp. 11438 - 11446,
    Journal articles | 2013
    Ives ML; Ma CS; Palendira U; Chan A; Bustamante J; Boisson-Dupuis S; Arkwright PD; Engelhard D; Averbuch D; Magdorf K; Roesler J; Peake J; Wong M; Adelstein S; Choo S; Smart JM; French MA; Fulcher DA; Cook MC; Picard C; Durandy A; Tsumura M; Kobayashi M; Uzel G; Casanova JL; Tangye SG; Deenick EK, 2013, 'Signal transducer and activator of transcription 3 (STAT3) mutations underlying autosomal dominant hyper-IgE syndrome impair human CD8+ T-cell memory formation and function', Journal of Allergy and Clinical Immunology, 132, pp. 400 - 411.e9,
    Journal articles | 2013
    Tangye SG; Ma CS; Brink R; Deenick EK, 2013, 'The good, the bad and the ugly-T FH cells in human health and disease', Nature Reviews Immunology, 13, pp. 412 - 426,
    Journal articles | 2013
    Tangye SG, 2013, 'To B1 or not to B1: that really is still the question!', Blood, 121, pp. 5109 - 5110,
    Journal articles | 2012
    Belz G; Tangye SG; Liston A, 2012, 'A new ICB sister journal focuses on clinical and translational immunology', Clinical and Translational Immunology, 1,
    Journal articles | 2012
    Chang PP; Barral P; Fitch J; Pratama A; Ma CS; Kallies A; Hogan JJ; Cerundolo V; Tangye SG; Bittman R; Nutt SL; Brink R; Godfrey DI; Batista FD; Vinuesa C, 2012, 'Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses', Nature Immunology, 13, pp. 35 - 43,
    Journal articles | 2012
    Cliffe S; Bloch D; Suryani S; Kamsteeg E; Avery D; Palendira U; Church J; Wainstein B; Trizzino A; Lefranc G; Akatcherian C; Megarbane A; Gilissen C; Moshous D; Reichenbach J; Misbah S; Salzer U; Abinun M; Ong P; Stepensky P; Ruga E; Ziegler JB; Wong M; Tangye SG; Lindeman R; Buckley M; Roscioli T, 2012, 'Clinical, molecular, and cellular immunologic findings in patients with SP110-associated veno-occlusive disease with immunodeficiency syndrome', Journal of Allergy and Clinical Immunology, 130, pp. 735 - 742,
    Journal articles | 2012
    Crequer A; Troeger A; Patino E; Ma CS; Picard C; Pedergnana V; Fieschi C; Lim A; Abhyankar A; Gineau L; Mueller-Fleckenstein I; Schmidt M; Taieb A; Kreuger J; Abela L; Tangye SG; Orth G; Williams DA; Casanova J-L; Jouanguy E, 2012, 'Human RHOH deficiency causes T cell defects and susceptibility to EV-HPV infections', Journal of Clinical Investigation, 122, pp. 3239 - 3247,
    Journal articles | 2012
    Hill ER; McAllister SC; Tangye S; Bhaduri-McIntosh S, 2012, 'Signal transducer and activator of transcription 3 (STAT3) controls susceptibility to Epstein-Barr virus reactivation in B cells', Infectious Agents and Cancer, 7,
    Journal articles | 2012
    Ma C; Avery D; Chan A; Batten ML; Bustamante J; Boisson-Dupuis S; Arkwright PD; Kreins AY; Averbuch D; Engelhard D; Magdorf K; Kilic S; Minegishi Y; Gray PE, 2012, 'Functional STAT3 deficiency compromises the generation of human T follicular helper cells', Blood, 119, pp. 3997 - 4008,
    Journal articles | 2012
    Ma CS; Deenick EK; Batten ML; Tangye SG, 2012, 'The origins, function, and regulation of T follicular helper cells', Journal of Experimental Medicine, 209, pp. 1241 - 1253,
    Journal articles | 2012
    Palendira U; Bell A; Ma CS; Abbott RJM; Phan TG; Riminton DS; Choo S; Smart J; Lougaris V; Giliani S; Buckley RH; Grimbacher B; Alvaro F; Klion AD; Nichols K; Adelstein S; Rickinson A; Tangye SG, 2012, 'Expansion of somatically reverted memory CD8+ T cells in patients with X-linked lymphoproliferative disease caused by selective pressure from Epstein-Barr virus', Journal of Experimental Medicine, 209, pp. 913 - 924,
    Journal articles | 2012
    Tangye SG; Brink R, 2012, 'A helping hand from neutrophils in T cell-independent antibody responses?', Nature Immunology, 13, pp. 111 - 113,
    Journal articles | 2012
    Tangye SG; Deenick EK; Palendira U; Ma CS, 2012, 'T cell-B cell interactions in primary immunodeficiencies', Annals of the New York Academy of Sciences, 1250, pp. 1 - 13,
    Journal articles | 2012
    Tangye SG, 2012, 'Defects in lymphocyte function and interactions in primary immunodeficiencies: insights into disease pathogenesis', Pathology, 44, pp. S39 - S39,
    Journal articles | 2011
    Cannons J; Tangye SG; Schwartzberg P, 2011, 'SLAM family receptors and SAP adaptors in immunity', Annual Review of Immunology, 29, pp. 665 - 705
    Journal articles | 2011
    Chevalier N; Jarrossay D; Ho E; Avery D; Ma CS; Yu D; Sallusto F; Tangye SG; MacKay CR, 2011, 'CXCR5 expressing human central memory CD4 T Cells and their relevance for humoral immune responses', Journal of Immunology, 186, pp. 5556 - 5568,
    Journal articles | 2011
    Cho JH; Kim HO; Webster KE; Palendira U; Hahm B; King C; Tangye SG; Sprent J; Kim KS, 2011, 'Calcineurin-dependent negative regulation of CD94/NKG2A expression on naive CD8+ T cells', Blood, 118, pp. 116 - 128,
    Journal articles | 2011
    Deenick EK; Ma CS; Brink R; Tangye SG, 2011, 'Regulation of T follicular helper cell formation and function by antigen presenting cells', Current Opinion in Immunology, 23, pp. 111 - 118,
    Journal articles | 2011
    McGuire HM; Vogelzang A; Ma CS; Hughes WE; Silveira PA; Tangye SG; Christ DU; Fulcher DA; Falcone M; King C, 2011, 'A subset of interleukin-21(+) chemokine receptor CCR9(+) T helper cells target accessory organs of the digestive system in autoimmunity', Immunity, 34, pp. 602 - 615,
    Journal articles | 2011
    Palendira U; Low C; Chan A; Hislop A; Ho E; Phan TG; Deenick EK; Cook MC; Riminton DS; Choo S; Loh R; Booth CA; Gaspar HB; Moretta A; Khanna ; Rickinson A; Tangye SG, 2011, 'Molecular pathogeneiss of EBV infection as revealed by analysis of XLP carriers with heterozygous expression of SAP', PLoS Biology, 9, pp. 1 - 17,
    Journal articles | 2011
    Randall KL; Chang SS; Ma CS; Fung I; Mei Y; Yabas M; Tan A; Arkwright PD; Suwairi WA; Reyes S; Yamazaki-Nakashimada MA; Garcia-Cruz D; Smart J; Picard C; Okada S; Jouanguy E; Casanova J-L; Lambert T; Cornall RJ; Russell S; Oliaro J; Tangye SG; Bertram EM; Goodnow CC, 2011, 'DOCK8 deficiency impairs CD8 T cell survival and function in humans and mice', Journal of Experimental Medicine, 208, pp. 2305 - 2320,
    Journal articles | 2011
    Recher M; Berglund L; Avery D; Cowan M; Gennery AR; Smart J; Peake J; Wong MB; Pai S-Y; Baxi S; Walter J; Palendira U; Tangye GA; Rice M; Brothers S; Al-Herz W; Ottegen H; Eibel H; Puck JM; Cattaneo F; Ziegler JB; Giliani S; Tangye SG; Notarangelo LD, 2011, 'IL-21 is the primary common gamma chain-binding cytokine required for human B-cell differentation in vivo', Blood, 118, pp. 6824 - 6835,
    Journal articles | 2011
    Tangye SG, 2011, 'Plasmacytoid DCs induce gutsy plasma cells', Immunity, 34, pp. 144 - 146,
    Journal articles | 2011
    Tangye SG, 2011, 'Staying alive: Regulation of plasma cell survival', Trends in Immunology, 32, pp. 595 - 602,
    Journal articles | 2010
    Avery D; Deenick EK; Ma CS; Suryani S; Simpson N; Chew G; Chan TD; Palendira U; Bustamante J; Boisson-Dupuis S; Choo S; Bleasel KE; Peake J; King C; French MA; Engelhard D; Al-Hajjar S; Al-Muhsen S; Magdorf K; Roesler J; Arkwright PD; Hissaria P; Riminton DS; Wong M; Brink R; Fulcher DA; Casanova J-L; Cook MC; Tangye SG, 2010, 'B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans', Journal of Experimental Medicine, 207, pp. 155 - 171,
    Journal articles | 2010
    Deenick EK; Chan A; Ma CS; Gatto D; Schwartzberg P; Brink R; Tangye SG, 2010, 'Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling', Immunity, 33, pp. 241 - 253,
    Journal articles | 2010
    Hislop A; Palendira U; Leese AM; Arkwright PD; Rohrlich PS; Tangye SG; Gaspar HB; Lankester AC; Moretta A; Rickinson A, 2010, 'Impaired Epstein-Barr virus-specific CD8+ T-cell function in X-linked lymphoproliferative disease is restricted to SLAM family-positive B-cell targets', Blood, 116, pp. 3249-57,
    Journal articles | 2010
    Ma CS; Tangye SG; Deenick EK, 2010, 'Human Th9 cells: inflammatory cytokines modulate IL-9 production through the induction of IL-21', Immunology and Cell Biology, 88, pp. 621 - 623,
    Journal articles | 2010
    Randall KL; Lambe T; Johnson A; Treanor B; Kucharska E; Domaschenz H; Whittle B; Tze LE; Enders A; Crockford TL; Bouriez-Jones T; Alston D; Cyster JG; Lenardo MJ; MacKay F; Deenick EK; Tangye SG; Chan TD; Camidge T; Brink R; Vinuesa CG; Batista FD; Cornall RJ; Goodnow CC, 2010, 'Erratum: Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production (Nature Immunology (2009) 10 (1283-1291))', Nature Immunology, 11, pp. 644,
    Journal articles | 2010
    Simpson N; Gatenby P; Wilson A; Malik S; Fulcher DA; Tangye SG; Manku H; Vyse TJ; Roncador G; Huttley G; Goodnow CC; Vinuesa C; Cook MC, 2010, 'Expansion of circulating T cells resembling follicular T helper cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus', Arthritis Care & Research, 62, pp. 234 - 244
    Journal articles | 2010
    Suryani S; Fulcher DA; Santner-Nanan B; Nanan R; Wong MB; Shaw P; Gibson J; Williams A; Tangye SG, 2010, 'Differential expression of CD21 identifies developmentally and functionally distinct subsets of human transitional B cells', Blood, 115, pp. 519 - 529,
    Journal articles | 2010
    Suryani S; Tangye SG, 2010, 'Therapeutic implications of advances in our understanding of transitional B-cell development in humans', Expert Review of Clinical Immunology, 6, pp. 765 - 775,
    Journal articles | 2010
    Tangye SG; Palendira U; Low C; Deenick EK; Chan A; Ma CS; Brink R; Alvaro F; Cook MC; Sean Riminton D; Nichols KE; Schwartzberg PL, 2010, 'Sap is necessary for mediating antigen-specific effector functions of CD4+ AND CD8+ T cells', Pathology, 42, pp. S45 - S45,
    Journal articles | 2010
    Tangye SG; Tarlinton DM, 2010, 'Memory B cells: Effectors of long-lived immune responses (European Journal of Immunology (2009) 39, (8) DOI 10.1002/eji.200939531)', European Journal of Immunology, 40, pp. 302,
    Journal articles | 2010
    Tangye SG; Tarlinton DM, 2010, 'Memory B cells: Effectors of long-lived immune responses (vol 39, pg 2065, 2009)', EUROPEAN JOURNAL OF IMMUNOLOGY, 40, pp. 302 - 302,
    Journal articles | 2010
    Tindall EA; Severi G; Hoang HN; Ma CS; Fernandez P; Southey MC; English DR; Hopper JL; Heyns CF; Tangye SG; Giles GG; Hayes V, 2010, 'Comprehensive analysis of the cytokine-rich chromosome 5q31.1 region suggests a role for IL-4 gene variants in prostate cancer risk', Carcinogenesis, 31, pp. 1748 - 1754,
    Journal articles | 2009
    Fulcher DA; Avery D; Fewings N; Berglund L; Wong S; Riminton D; adelstein S; Tangye SG, 2009, 'Invariant natural killer (iNK) T cell deficiency in patients with common variable immunodeficiency', Clinical and Experimental Immunology, 157, pp. 365 - 369
    Journal articles | 2009
    Good K; Avery D; Tangye SG, 2009, 'Resting human memory B cells are intrinsically programmed for enhanced survival and responsiveness to diverse stimuli compared to naive B cells', Journal of Immunology, 182, pp. 890 - 901,
    Journal articles | 2009
    Ma CS; Suryani S; Avery D; Chan A; Nanan R; Santner-Nanan B; Tangye SG; Deenick E, 2009, 'Early commitment of naive human CD4(+) T cells to the T follicular helper (T(FH)) cell lineage is induced by IL-12', Immunology and Cell Biology, 87, pp. 590 - 600,
    Journal articles | 2009
    Ma CS; Tangye SG, 2009, 'Helping the Helpers!', Immunity, 31, pp. 12 - 14
    Journal articles | 2009
    Randall KL; Lambe T; Johnson A; Treanor B; Kucharska E; Domaschenz H; Whittle B; Tze LE; Enders A; Crockford TL; Bouriez-Jones T; Alston D; Cyster JG; Lenardo MJ; Mackay F; Deenick EK; Tangye SG; Chan TD; Camidge T; Brink R; Vinuesa C; Batista FD; Cornall RJ; Goodnow CC, 2009, 'Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production', Nature Immunology, 10, pp. 1283 - 1291,
    Journal articles | 2009
    Tangye SG; Cook MC; Fulcher DA, 2009, 'Insights into the role of STAT3 in human lymphocyte differentiation as revealed by the hyper-IgE syndrome', Journal of Immunology, 182, pp. 21 - 28
    Journal articles | 2009
    Tangye SG; Cook MC, 2009, 'Primary immune deficiencies affecting lymphocyte differentiation: Lessons from the spectrum of resulting infections', International Immunology, 21, pp. 1003 - 1011
    Journal articles | 2009
    Tangye SG; Tarlinton D, 2009, 'Memory B cells: effectors of long-lived immune responses', European Journal of Immunology, 39, pp. 2065 - 2075
    Journal articles | 2008
    Avery D; Bryant V; Ma C; Malefyt R; Tangye SG, 2008, 'IL-21-induced isotype switching to IgG and IgA by human naive B cells is differentially regulated by IL-4', Journal of Immunology, 181, pp. 1767 - 1779
    Journal articles | 2008
    Avery D; Ma C; Bryant V; Santner-Nanan B; Nanan R; Wong MB; Fulcher DA; Cook M; Tangye SG, 2008, 'STAT3 is required for IL-21-induced secretion of IgE from human naive B cells', Blood, 112, pp. 1784 - 1793
    Journal articles | 2008
    Chaganti S; Ma C; Bell A; Croom-Carter D; Hislop A; Tangye SG; Rickinson A, 2008, 'Epstein-Barr virus persistence in the absence of conventional memory B cells: IgM(+)IgD(+)CD27(+) B cells harbor the virus in X-linked lymphoproliferative disease patients', Blood, 112, pp. 672 - 679,
    Journal articles | 2008
    Deenick E; Tangye SG, 2008, 'Immunology: Helpful T cells are sticky', Nature, 455, pp. 745 - 746
    Journal articles | 2008
    Deenick EK; Tangye SG, 2008, 'Autoimmunity: IL-21: A new player in Th17-cell differentiation (Immunology and Cell Biology (2007) 85, (503-505) DOI: 10.1038/sj.icb.7100114)', Immunology and Cell Biology, 86, pp. 478,
    Journal articles | 2008
    King CK; Tangye SG; MacKay CR, 2008, 'T follicular helper (T-FH) cells in normal and dysregulated immune responses', Annual Review of Immunology, 26, pp. 741 - 766,
    Journal articles | 2008
    Ma CS; Chew G; Simpson N; Priyadarshi A; Wong M; Grimbacher B; Fulcher DA; Tangye SG; Cook M, 2008, 'Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3', Journal of Experimental Medicine, 205, pp. 1551 - 1557
    Journal articles | 2008
    Rosen DM; Cao W; Avery D; Tangye SG; Liu Y; Houchins J; Lanier L, 2008, 'Functional consequences of interactions between-human NKR-P1A and its ligand LLT1 expressed on activated dendritic cells and B cells', Journal of Immunology, 180, pp. 6508 - 6517
    Journal articles | 2007
    Bryant V; Ma C; Avery D; Li Y; Good K; Corcoran L; Malefyt R; Tangye SG, 2007, 'Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells: Predominant role of IL-21 produced by CXCR5(+) T follicular helper cells', Journal of Immunology, 179, pp. 8180 - 8190
    Journal articles | 2007
    Deenick E; Tangye SG, 2007, 'Autoimmunity IL-21: a new player in Th17-cell differentiation', Immunology and Cell Biology, 85, pp. 503 - 505
    Journal articles | 2007
    Good K; Tangye SG, 2007, 'Decreased expression of Kruppel-like factors in memory B cells induces the rapid response typical of secondary antibody responses', Proceedings of the National Academy of Sciences of the United States of America, 104, pp. 13420 - 13425
    Journal articles | 2007
    Ma C; Nichols K; Tangye SG, 2007, 'Regulation of cellular and humoral immune responses by the SLAM and SAP families of molecules', Annual Review of Immunology, 25, pp. 337 - 379
    Journal articles | 2007
    Mackay F; Groom JR; Tangye SG, 2007, 'An important role for B-cell activation factor and B cells in the pathogenesis of Sjogren`s syndrome', Current Opinion in Rheumatology, 19, pp. 406 - 413
    Journal articles | 2007
    Tangye SG; Avery DT; Bryant VL; Ma CS, 2007, 'Follicular CD4+T helper cells induce human B cells to undergo Ig isotype switching and differentiation to Ig-secreting cells through the production of IL-21', JOURNAL OF IMMUNOLOGY, 178,
    Journal articles | 2007
    Tangye SG; Good K, 2007, 'Human IgM(+)CD27(+) B cells: Memory B cells or `memory` B cells?', Journal of Immunology, 179, pp. 13 - 19
    Journal articles | 2006
    Cuss AK; Avery DT; Cannons JL; Yu LJ; Nichols KE; Shaw PJ; Tangye SG, 2006, 'Expansion of functionally immature transitional B cells is associated with human-immunodeficient states characterized by impaired humoral immunity', Journal of Immunology, 176, pp. 1506 - 1516,
    Journal articles | 2006
    Good K; Bryant V; Tangye SG, 2006, 'Kinetics of human B cell behavior and amplification of proliferative responses following stimulation with IL-21', Journal of Immunology, 177, pp. 5236 - 5247
    Journal articles | 2006
    Gu C; Tangye SG; Sun XF; Luo Y; Lin Z; Wu J, 2006, 'The X-linked lymphoproliferative disease gene product SAP associates with PAK-interacting exchange factor and participates in T cell activation', Proceedings of the National Academy of Sciences of the United States of America, 103, pp. 14447 - 14452
    Journal articles | 2006
    Hare NJ; Ma CS; Alvaro F; Nichols KE; Tangye SG, 2006, 'Missense mutations in SH2D1A identified in patients with X-linked lymphoproliferative disease differentially affect the expression and function of SAP', International Immunology, 18, pp. 1055 - 1065,
    Journal articles | 2006
    Liu SM; Xavier R; Good K; Newton R; Sisavanh M; Zimmer S; Deng C; Silva D; Frost M; Tangye SG; Rolph MS; Mackay C; Chtanova T, 2006, 'Immune cell transcriptome datasets reveal novel leukocyte subset-specific genes and genes associated with allergic processes', Journal of Allergy and Clinical Immunology, 118, pp. 496 - 503,
    Journal articles | 2006
    Ma CS; Pittaluga S; Avery DT; Hare NJ; Maric I; Klion AD; Nichols KE; Tangye SG, 2006, 'Selective generation of functional somatically mutated IgM +CD27+, but not Ig isotype-switched, memory B cells in X-linked lymphoproliferative disease', Journal of Clinical Investigation, 116, pp. 322 - 333,
    Journal articles | 2006
    Seddiki N; Santner-Nanan B; Tangye SG; Alexander SI; Solomon M; Lee S; Nanan R; Fazekas De Saint Groth B, 2006, 'Persistence of naive CD45RA+ regulatory T cells in adult life', Blood, 107, pp. 2830 - 2838,
    Journal articles | 2006
    Tangye S; Mackay F, 2006, 'B Cells and Autoimmunity', , pp. 139 - 156,
    Journal articles | 2006
    Tangye SG; Bryant V; Cuss A; Good K, 2006, 'BAFF, APRIL and human B cell disorders', Seminars in Immunology, 18, pp. 305 - 317
    Journal articles | 2005
    Avery DT; Ellyard JI; Mackay F; Corcoran LM; Hodgkin PD; Tangye SG, 2005, 'Erratum: Increased expression of CD27 on activated human memory B cells correlates with their commitment to the plasma cell lineage (Journal of Immunology (2005) 174 (4034-4042))', Journal of Immunology, 174, pp. 5885,
    Journal articles | 2005
    Avery DT; Ellyard JI; Mackay F; Corcoran LM; Hodgkin PD; Tangye SG, 2005, 'Increased expression of CD27 on activated human memory B cells correlates with their commitment to the plasma cell lineage (vol 174, pg 4034, 2005)', JOURNAL OF IMMUNOLOGY, 174, pp. 5885 - 5885,
    Journal articles | 2005
    Dupré L; Andolfi G; Tangye SG; Clementi R; Locatelli F; Aricò M; Aiuti A; Roncarolo MG, 2005, 'SAP controls the cytolytic activity of CD8+ T cells against EBV-infected cells', Blood, 105, pp. 4383 - 4389,
    Journal articles | 2005
    Ma CS; Hare NJ; Nichols KE; Dupré L; Andolfi G; Roncarolo M-G; Adelstein S; Hodgkin PD; Tangye SG, 2005, 'Impaired humoral immunity in X-linked lymphoproliferative disease is associated with defective IL-10 production by CD4+ T cells', Journal of Clinical Investigation, 115, pp. 1049 - 1059,
    Journal articles | 2005
    Ma CS; Hare NJ; Nichols KE; Dupré L; Andolfi G; Roncarolo MG; Adelstein S; Hodgkin PD; Tangye SG, 2005, 'Impaired humoral immunity in X-linked lymphoproliferative disease is associated with defective IL-10 production by CD4+ T cells', Journal of Clinical Investigation, 115, pp. 1049 - 1059,
    Journal articles | 2005
    Nichols KE; Hom J; Gong SY; Ganguly A; Ma CS; Cannons JL; Tangye SG; Schwartzberg PL; Koretzky GA; Stein PL, 2005, 'Regulation of NKT cell development by SAP, the protein defective in XLP', Nature Medicine, 11, pp. 340 - 345,
    Journal articles | 2005
    Nichols KE; Ma CS; Cannons JL; Schwartzberg PL; Tangye SG, 2005, 'Molecular and cellular pathogenesis of X-linked lymphoproliferative disease', Immunological Reviews, 203, pp. 180 - 199,
    Journal articles | 2004
    Avery DT; Kalled SL; Ellyard JI; Ambrose C; Bixler SA; Thien M; Brink R; Mackay F; Hodgkin PD; Tangye SG, 2004, 'BAFF selectively enhances the survival of plasmablasts generated from human memory B cells', Journal of Clinical Investigation, 113, pp. 1069 - 1069,
    Journal articles | 2004
    Avery DT; Kalled SL; Ellyard JI; Ambrose C; Bixler SA; Thien M; Brink R; Mackay F; Hodgkin PD; Tangye SG, 2004, 'Erratum: BAFF selectively enhances the survival of plasmablasts generated from human memory B cells (Journal of Clinical Investigation (2003) 112 (286-297) doi:10.1172/JCI200318025)', Journal of Clinical Investigation, 113, pp. 1069,
    Journal articles | 2004
    Ellyard JI; Avery DT; Phan TG; Hare NJ; Hodgkin PD; Tangye SG, 2004, 'Antigen-selected, immunoglobulin-secreting cells persist in human spleen and bone marrow', Blood, 103, pp. 3805 - 3812,
    Journal articles | 2004
    Hasbold J; Corcoran LM; Tarlinton DM; Tangye SG; Hodgkin PD, 2004, 'Evidence from the generation of immunoglobulin G-secreting cells that stochastic mechanisms regulate lymphocyte differentiation', Nature Immunology, 5, pp. 55 - 63,
    Journal articles | 2004
    Ma CS; Hodgkin PD; Tangye SG, 2004, 'Automatic generation of lymphocyte heterogeneity: Division-dependent changes in the expression of CD27, CCR7 and CD45 by activated human naive CD4+ T cells are independently regulated', Immunology and Cell Biology, 82, pp. 67 - 74,
    Journal articles | 2004
    Nichols KE; Hom J; Ganguly A; Ma CS; Tangye SG; Cannons JL; Schwartzberg PL; Koretzky GA; Stein PL, 2004, 'Regulation of NKT Cell Development by Sap, the Adaptor Mutated in X-Linked Lymphoproliferative Disease.', Blood, 104, pp. 317 - 317,
    Journal articles | 2004
    Tangye SG; Hodgkin PD, 2004, 'Divide and conquer: The importance of cell division in regulating B-cell responses', Immunology, 112, pp. 509 - 520,
    Journal articles | 2003
    Avery DT; Kalled SL; Ellyard JI; Ambrose C; Bixler SA; Thien M; Brink R; MacKay F; Hodgkin PD; Tangye SG, 2003, 'BAFF selectively enhances the survival of plasmablasts generated from human memory B cells', Journal of Clinical Investigation, 112, pp. 286 - 297,
    Journal articles | 2003
    Avery DT; Kalled SL; Ellyard JI; Ambrose C; Bixler SA; Thien M; Brink R; Mackay F; Hodgkin PD; Tangye SG, 2003, 'BAFF selectively enhances the survival of plasmablasts generated from human memory B cells', Journal of Clinical Investigation, 112, pp. 286 - 297,
    Journal articles | 2003
    Tangye SG; Avery DT; Deenick EK; Hodgkin PD, 2003, 'Intrinsic differences in the proliferation of naive and memory human B cells as a mechanism for enhanced secondary immune responses', Journal of Immunology, 170, pp. 686 - 694,
    Journal articles | 2003
    Tangye SG; Avery DT; Hodgkin PD, 2003, 'A division-linked mechanism for the rapid generation of Ig-secreting cells from human memory B cells', Journal of Immunology, 170, pp. 261 - 269,
    Journal articles | 2003
    Tangye SG; Nichols KE; Hare NJ; Van de Weerdt BCM, 2003, 'Functional requirements for interactions between CD84 and Src homology 2 domain-containing proteins and their contribution to human T cell activation', Journal of Immunology, 171, pp. 2485 - 2495,
    Journal articles | 2002
    Tangye SG; Ferguson A; Avery DT; Ma CS; Hodgkin PD, 2002, 'Isotype switching by human B cells is division-associated and regulated by cytokines', Journal of Immunology, 169, pp. 4298 - 4306,
    Journal articles | 2002
    Tangye SG; Van De Weerdt BCM; Avery DT; Hodgkin PD, 2002, 'CD84 is up-regulated on a major population of human memory B cells and recruits the SH2 domain containing proteins SAP and EAT-2', European Journal of Immunology, 32, pp. 1640 - 1649, http://dx.doi.org/10.1002/1521-4141(200206)32:6<1640::AID-IMMU1640>3.0.CO;2-S
    Journal articles | 2001
    Baker JE; Majeti R; Tangye SG; Weiss A, 2001, 'Protein tyrosine phosphatase CD148-mediated inhibition of T-cell receptor signal transduction is associated with reduced LAT and phospholipase Cγ1 phosphorylation', Molecular and Cellular Biology, 21, pp. 2393 - 2403,
    Journal articles | 2001
    Weston KM; Tangye SG; Dunn RD; Smith A; Morris MB; Raison RL, 2001, 'IgM expressed by leukemic CD5+ B cells binds mouse immunoglobulin light chain', Journal of Molecular Recognition, 14, pp. 245 - 253,
    Journal articles | 2000
    Tangye SG; Cherwinski H; Lanier LL; Phillips JH, 2000, '2B4-mediated activation of human natural killer cells', Molecular Immunology, 37, pp. 493 - 501,
    Journal articles | 2000
    Tangye SG; Phillips JH; Lanier LL; Nichols KE, 2000, 'Cutting edge: Functional requirement for SAP in 2B4-mediated activation of human natural killer cells as revealed by the X-linked lymphoproliferative syndrome', Journal of Immunology, 165, pp. 2932 - 2936,
    Journal articles | 2000
    Tangye SG; Phillips JH; Lanier LL, 2000, 'The CD2-subset of the Ig superfamily of cell surface molecules: Receptor-ligand pairs expressed by NK cells and other immune cells', Seminars in Immunology, 12, pp. 149 - 157,
    Journal articles | 1999
    Castro AG; Hauser TM; Cocks BG; Abrams J; Zurawski S; Churakova T; Zonin F; Robinson D; Tangye SG; Aversa G; Nichols KE; De Vries JE; Lanier LL; O'Garra A, 1999, 'Molecular and functional characterization of mouse signaling lymphocytic activation molecule (SLAM): Differential expression and responsiveness in Th1 and Th2 cells', Journal of Immunology, 163, pp. 5860 - 5870
    Journal articles | 1999
    Tangye SG; Lazetic S; Woollatt E; Sutherland GR; Lanier LL; Phillips JH, 1999, 'Cutting edge: Human 2B4, an activating NK cell receptor, recruits the protein tyrosine phosphatase SHP-2 and the adaptor signaling protein SAP', Journal of Immunology, 162, pp. 6981 - 6985
    Journal articles | 1998
    Tangye SG; Aversa G; Lanier LL; De Vries JE; Phillips JH, 1998, 'CD148: A cell-surface phosphatase involved in T cell activation', FASEB Journal, 12
    Journal articles | 1998
    Tangye SG; Liu YJ; Aversa G; Phillips JH; De Vries JE, 1998, 'Identification of functional human splenic memory B cells by expression of CD148 and CD27', Journal of Experimental Medicine, 188, pp. 1691 - 1703,
    Journal articles | 1998
    Tangye SG; Phillips JH; Lanier LL; De Vries JE; Aversa G, 1998, 'CD148: A receptor-type protein tyrosine phosphatase involved in the regulation of human T cell activation', Journal of Immunology, 161, pp. 3249 - 3255
    Journal articles | 1998
    Tangye SG; Weston KM; Raison RL, 1998, 'Interleukin-10 inhibits the in vitro proliferation of human activated leukemic CD5+ B-Cells', Leukemia and Lymphoma, 31, pp. 121 - 130,
    Journal articles | 1998
    Tangye SG; Wu J; Aversa G; De Vries JE; Lanier LL; Phillips JH, 1998, 'Cutting edge: Negative regulation of human T cell activation by the receptor-type protein tyrosine phosphatase CD148', Journal of Immunology, 161, pp. 3803 - 3807
    Journal articles | 1997
    Tangye SG; Aversa G; Phillips JH; de Vries JE, 1997, 'Characterization of a cell surface molecule involved in T-cell activation', Immunology Letters, 56, pp. 1 - 1,
    Journal articles | 1997
    Tangye SG; Raison RL, 1997, 'Human cytokines suppress apoptosis of leukaemic CD5+ B cells and preserve expression of bcl-2', Immunology and Cell Biology, 75, pp. 127 - 135,
    Journal articles | 1997
    Tangye SG; Weston KM; Raison RL, 1997, 'Cytokines and cross-linking of sIgM augment PMA-induced activation of human leukaemic CD5+ B cells', Immunology and Cell Biology, 75, pp. 561 - 567,
    Journal articles | 1996
    Tangye SG; Raison RL, 1996, 'Leukaemic CD5+ B-cell apoptosis: Co-incidence of cell death and DNA fragmentation with reduced bcl-2 expression', British Journal of Haematology, 92, pp. 950 - 953,
    Journal articles | 1995
    TANGYE SG; WESTON KM; RAISON RL, 1995, 'Phorbol ester activates CD5+ leukaemic B cells via a T cell‐independent mechanism', Immunology and Cell Biology, 73, pp. 44 - 51,
  • Working Papers | 2022
    Manry J; Bastard P; Gervais A; Le Voyer T; Rosain J; Philippot Q; Michailidis E; Hoffmann H-H; Eto S; Garcia-Prat M; Bizien L; Parra-Martínez A; Yang R; Haljasmägi L; Migaud M; Särekannu K; Maslovskaja J; de Prost N; Tandjaoui-Lambiotte Y; Luyt C-E; Amador-Borrero B; Gaudet A; Poissy J; Morel P; Richard P; Cognasse F; Troya J; Trouillet-Assant S; Belot A; Saker K; Garçon P; Rivière JG; Lagier J-C; Gentile S; Rosen L; Shaw E; Morio T; Tanaka J; Dalmau D; Tharaux P-L; Sene D; Stepanian A; Mégarbane B; Triantafyllia V; Fekkar A; Heath J; Franco J; Anaya J-M; Solé-Violán J; Imberti L; Biondi A; Bonfanti P; Castagnoli R; Delmonte O; Zhang Y; Snow A; Holland S; Biggs C; Moncada-Vélez M; Arias A; Lorenzo L; Boucherit S; Anglicheau D; Planas A; Haerynck F; Duvlis S; Nussbaum R; Ozcelik T; Keles S; Bousfiha A; El Bakkouri J; Ramirez-Santana C; Paul S; Pan-Hammarstrom Q; Hammarstrom L; Dupont A; Kurolap A; Metz C; Aiuti A; Casari G; Lampasona V; Ciceri F; Barreiros L; Dominguez-Garrido E; Vidigal M; Zatz M; van de Beek D; Sahanic S; Tancevski I; Stepanovskyy Y; Boyarchuk O; Nukui Y; Tsumura M; Vidaur L; Tangye S; Burrel S; Duffy D; Quintana-Murci L; Klocperk A; Kann N; Shcherbina A; Lau Y-L; Leung D; Coulongeat M; Marlet J; Koning R; Reyes L; Chauvineau-Grenier A; Venet F; Monneret G; Nussenzweig M; Arrestier R; Boudhabhay I; Baris-Feldman H; Hagin D; Wauters J; Meyts I; Dyer A; Kennelly S; Bourke N; Halwani R; Sharif-Askari F; Dorgham K; Sallette J; Mehlal-Sedkaoui S; AlKhater S; Rigo-Bonnin R; Morandeira F; Roussel L; Vinh D; Erikstrup C; Condino-Neto A; Prando C; Bondarenko A; Spaan A; Gilardin L; Fellay J; Lyonnet S; Bilguvar K; Lifton R; Mane S; Anderson M; Boisson B; Béziat V; Zhang S-Y; Andreakos E; Hermine O; Pujol A; Peterson P; Mogensen TH; Rowen L; Mond J; Debette S; deLamballerie X; Burdet C; Bouadma L; Zins M; Soler-Palacin P; Colobran R; Gorochov G; Solanich X; Susen S; Martinez-Picado J; Raoult D; Vasse M; Gregersen P; Rodríguez-Gallego C; Piemonti L; Notarangelo L; Su H; Kisand K; Okada S; Puel A; Jouanguy E; Rice C; Tiberghien P; Zhang Q; Casanova J-L; Abel L; Cobat A, 2022, The risk of COVID-19 death is much greater and age-dependent with type I IFN autoantibodies., ,
  • Preprints | 2024
    Bier J; Lau A; Jackson KJL; Ruiz-Diaz S; Brink R; Tangye S; Deenick E, 2024, Both T and B cells contribute to dysregulated activation and differentiation of CD4+T cells in Activated PI3K delta syndrome 1,
    Preprints | 2024
    Forkgen J; Masle-Farquhar E; Fontaine Y; Russell A; Ji S; Peters TJ; Qiao Z; Geaghan M; Jackson KJL; Hammond JM; Deveson IW; David C; Lemberg DA; Gupta N; Fuentes-Bolanos N; Mustjoki S; Hwa V; Tangye SG; Gray PE; Siggs OM, 2024, Sequential mosaic variants inKRASandSTAT5Bassociated with a mixed phenotype of two acquired errors of immunity,
    Preprints | 2024
    Singh M; Louie RHY; Samir J; Field MA; Milthorpe C; Aldiriki T; Mackie J; Roper E; Faulks M; Jackson KJL; Calcino A; Hardy MY; Blombery P; Amos TG; Deveson IW; Read SA; Shek D; Guerin A; Ma CS; Tangye SG; Sabatino AD; Lenti MV; Pasini A; Ciccocioppo R; Ahlenstiel G; Suan D; Tye-Din JA; Goodnow CC; Luciani F, 2024, Expanded T cell clones with lymphoma driver somatic mutations in refractory celiac disease,
    Preprints | 2023
    Marchal A; Cirulli ET; Neveux I; Bellos E; Thwaites RS; Schiabor Barrett KM; Zhang Y; Nemes-Bokun I; Kalinova M; Catchpole A; Tangye SG; Spaan AN; Lack JB; Ghosn J; Burdet C; Gorochov G; Tubach F; Hausfater P; COVID Human Genetic Effort ; COVIDeF Study Group ; French COVID Cohort Study Group ; CoV-Contact Cohort ; COVID-STORM Clinicians ; COVID Clinicians ; Orchestra Working Group ; Amsterdam UMC Covid-19 Biobank ; NIAID-USUHS COVID Study Group ; Dalgard CL; Zhang S-Y; Zhang Q; Chiu C; Fellay J; Grzymski JJ; Sancho-Shimizu V; Abel L; Casanova J-L; Cobat A; Bolze A, 2023, Lack of association between HLA and asymptomatic SARS-CoV-2 infection.,
    Preprints | 2023
    Noma K; Tsumura M; Nguyen T; Asano T; Sakura F; Tamaura M; Imanaka Y; Mizoguchi Y; Karakawa S; Hayakawa S; Shoji T; Hosokawa J; Izawa K; Ling Y; Casanova J-L; Puel A; Tangye SG; Ma CS; Ohara O; Okada S, 2023, Isolated chronic mucocutaneous candidiasis due to a novel duplication variant of IL17RC.,
    Preprints | 2023
    Voyer TL; Gervais A; Rosain J; Parent A; Cederholm A; Rinchai D; Bizien L; Hancioglu G; Philippot Q; Gueye MS; Luxman MR; Renkilaraj M; Ogishi M; Soudée C; Migaud M; Rozenberg F; Momenilandi M; Riller Q; Imberti L; Delmonte O; Müller G; Keller B; Orrego J; Gallego WA; Rubin T; Emiroglu M; Parvaneh N; Eriksson D; Aranda-Guillen M; Berrios DI; Vong L; Katelaris CH; Mustillo P; Rädler J; Bohlen J; Celik JB; Astudillo C; Winter S; Guichard A; Béziat V; Bustamante J; Pan-Hammarström Q; Zhang Y; Rosen LB; Holland SM; Kenney H; Boztuğ K; Mahlaoui N; Latour S; Abraham R; Lougaris V; Hauck F; Sediva A; Atschekzei F; Poli MC; Slatter MA; Palterer B; Keller MD; Pinzon-Charry A; Sullivan A; Droney L; Suan D; Aladjidi N; Hie M; Lazaro E; Franco J; Keles S; Malphette M; Pasquet M; Maccari ME; Meinhardt A; Ikinciogullari A; Shahrooei M; Celmeli F; Frosk P; Goodnow CC; Gray PE; Belot A; Kuehn HS; Rosenzweig SD; Licciardi F; Servettaz A; Barlogis V; Guenno GL; Herrmann V-M; Kuijpers T; Ducoux G; Sarrot-Reynauld F; Schuetz C; Cunningham-Rundles C; Rieux-Laucat F; Tangye SG; Sobacchi C; Doffinger R; Warnatz K; Grimbacher B; Fieschi C; Berteloot L; Bryant V; Assant ST; Notarangelo LD; Su H; Neven B; Abel L; Zhang Q; Boisson B; Cobat A; Jouanguy E; Kampe O; Bastard P; Roifman C; Landegren N; Anderson MS; Casanova J-L; Puel A, 2023, Impaired thymic AIRE expression underlies autoantibodies against type I IFNs in humans with inborn errors of the alternative NF-kB pathway,
    Preprints | 2022
    Akerman A; Milogiannakis V; Jean T; Esneau C; Silva MR; Ison T; Fitcher C; Lopez J; Chandra D; Naing Z; Caguicla J; Li D; Walker G; Amatayakul-Chantler S; Roth N; Manni S; Hauser T; Barnes T; Condylios A; Yeang M; Wong M; Foster CSP; Sato K; Lee S; Song Y; Mao L; Sigmund A; Phu A; Vande More AM; Hunt S; Douglas M; Caterson I; Sandgren K; Bull R; Lloyd A; Triccas J; Tangye S; Bartlett N; Darley D; Matthews G; Stark D; Rawlinson W; Murrell B; Brilot F; Cunningham A; Kelleher A; Aggarwal A; Turville S, 2022, Emergence and antibody evasion of BQ, BA.2.75 and SARS-CoV-2 recombinant sublineages in the face of maturing antibody breadth at the population level,
    Preprints | 2022
    Masle-Farquhar E; Jackson KJL; Peters T; Al-Eryani G; Singh M; Payne K; Rao G; Apps G; Kingham J; Jara C; Skvortsova K; Swarbrick A; Ma C; Suan D; Uzel G; Chua I; Leiding J; Heiskanen K; Preece K; Kainulainen L; O’Sullivan M; Cooper M; Seppänen MRJ; Mustjoki S; Brothers S; Vogel T; Brink R; Tangye S; Reed J; Goodnow C, 2022, STAT3gain-of-function mutations connect leukemia with autoimmune disease by pathological dysregulation of NKG2DhiCD8 killer T cells,
    Preprints | 2022
    Zammit N; Gray P; Siggs O; Yap JY; Russell A; Cultrone D; Warren J; Walters S; Brink R; Zahra D; Burnett D; Gayevskiy V; Minoche A; Ziegler J; Craig M; Wong M; Benitez-Aguirre P; Teo J; Cowley M; Dinger M; Tangye S; Burke C; Phan T; Goodnow C; Grey S, 2022, Environmental and genetic disease modifiers of haploinsufficiency of A20,
    Conference Papers | 2021
    Bier J; Lau A; Brink RA; Ruiz-Diaz S; Lenthall H; Tangye S; Deenick E, 2021, 'T cell dysfunction in Activated P13K delta Syndrome explained by cell intrinsic and extrinsic components', in JOURNAL OF IMMUNOLOGY, AMER ASSOC IMMUNOLOGISTS,
    Preprints | 2021
    Masle-Farquhar E; Peters T; Jackson KJL; Singh M; Ma C; Suan D; Uzel G; Chua I; Leiding J; Heiskanen K; Preece K; Kainulainen L; O’Sullivan M; Cooper M; Seppänen MRJ; Mustjoki S; Brothers S; Vogel T; Brink R; Tangye S; Reed J; Goodnow C, 2021, Overactive STAT3 drives accumulation of disease-associated CD21lowB cells,
    Conference Abstracts | 2021
    Tangye S, 2021, 'Somatic reversion of pathogenic DOCK8 variants alters lymphocyte differentiation and function to effectively cure DOCK8 deficiency', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Vol. 41, pp. S16 - S16,
    Preprints | 2020
    Hensen L; Illing PT; Clemens EB; Nguyen THO; Koutsakos M; van de Sandt CE; Mifsud NA; Nguyen A; Szeto C; Chua BY; Halim H; Rizzetto S; Luciani F; Loh L; Grant EJ; Saunders PM; Brooks AG; Rockman S; Kotsimbos TC; Cheng AC; Richards M; Westall GP; Wakim LM; Loudovaris T; Mannering SI; Elliott M; Tangye SG; Jackson DC; Flanagan KL; Rossjohn J; Gras S; Davies J; Miller A; Tong SYC; Purcell AW; Kedzierska K, 2020, CD8+T-cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph,
    Conference Abstracts | 2020
    Humphrey A; Tangye S; Preece K, 2020, 'IRAK4 Deficiency Presenting with Severe Viral Infections and Recurrent Kingella Kingae Sepsis', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, CO, Denver, Vol. 40, pp. S74 - S75, presented at Annual Meeting of the Clinical-Immunology-Society (CIS) / Immune Deficiency and Dysregulation North American Conference, CO, Denver, 02 April 2020 - 05 April 2020,
    Conference Papers | 2020
    Kong X-F; Worley L; Rinchai D; Bondet V; Jithesh P; Goulet M; Nonnotte E; Gurtler N; Liu L; Migaud M; Elanbari M; Habib T; Ma C; Bustamante J; Abel L; Ravel A; Lyonnet S; Duffy D; Chaussabel D; Casanova J-L; Tangye S; Boisson-Dupuis S; Puel A, 2020, 'Three Copies of Four Interferon Receptor Genes Underlie Type I Interferonopathies In Down Syndrome', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, CO, Denver, pp. S9 - S9, presented at Annual Meeting of the Clinical-Immunology-Society (CIS) / Immune Deficiency and Dysregulation North American Conference, CO, Denver, 02 April 2020 - 05 April 2020,
    Conference Papers | 2020
    Leiding J; Vogel T; Jadoul VG; Mhaskar R; Cooper M; O'Sullivan M; Giovanni-Chami L; Thatayatikom AB; Bauer CS; Seppanen M; Taskinen M; Hamalainen S; Adeli M; Formankova R; Heeg M; Pozos T; Szabolcs P; Morio T; Chua I; Hague R; Hambleton S; Tangye S; Gennery A; Cunningham-Rundles C; Su H; Rao VK; Sogkas G; Milner J; Ehl S; Forbes L, 2020, 'The Natural History Of STAT3 GOF Syndrome - The Range Of Clinical Manifestations And Treatment Options', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, CO, Denver, pp. S144 - S146, presented at Annual Meeting of the Clinical-Immunology-Society (CIS) / Immune Deficiency and Dysregulation North American Conference, CO, Denver, 02 April 2020 - 05 April 2020,
    Conference Papers | 2020
    Masle-Farquhar E; Payne K; Singh M; Rao G; Al-Eryani G; Jara C; Jackson K; Brink RA; Tangye S; Reed J; Goodnow CC, 2020, 'The effects of germline STAT3-activating mutations from autoimmunity and lymphoid malignancy on mouse and human T cells', in JOURNAL OF IMMUNOLOGY, AMER ASSOC IMMUNOLOGISTS, HI, Honolulu, presented at Annual Meeting of the American-Association-of-Immunologists - Immunology 2020, HI, Honolulu, 08 May 2020 - 12 May 2020,
    Conference Papers | 2020
    Tangye S, 2020, 'Regulation Of Humoral Immunity By Cytokine-Mediated STAT Signalling - Lessons From Inborn Errors Of Immunity', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, CO, Denver, pp. S43 - S43, presented at Annual Meeting of the Clinical-Immunology-Society (CIS) / Immune Deficiency and Dysregulation North American Conference, CO, Denver, 02 April 2020 - 05 April 2020,
    Preprints | 2020
    Yang R; Mele F; Worley L; Langlais D; Rosain J; Benhsaien I; Elarabi H; Croft CA; Doisne J-M; Zhang P; Weisshaar M; Jarrossay D; Latorre D; Shen Y; Han J; Gruber C; Markle J; Al Ali F; Rahman M; Khan T; Seeleuthner Y; Kerner G; Husquin LT; Maclsaac JL; Jeljeli M; Ailal F; Kobor MS; Oleaga-Quintas C; Roynard M; Bourgey M; El Baghdadi J; Boisson-Dupuis S; Puel A; Batteux F; Rozenberg F; Marr N; Pan-Hammarström Q; Bogunovic D; Quintana-Murci L; Carroll T; Ma CS; Abel L; Bousfiha A; Di Santo JP; Glimcher LH; Gros P; Tangye SG; Sallusto F; Bustamante J; Casanova J-L, 2020, Human T-bet governs innate and innate-like adaptive IFN-γ immunity against mycobacteria,
    Conference Abstracts | 2019
    Masle-Farquhar E; Payne K; Jackson K; Rao G; Singh M; El-Eryani G; Brink R; Tangye S; Reed J; Goodnow C, 2019, 'The effects of germline STAT3-activating mutations from autoimmunity and lymphoid malignancy on mouse and human T cell development and function', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY, PEOPLES R CHINA, Beijing, Vol. 49, pp. 901 - 901, presented at 17th International Congress of Immunology of the International-Union-of-Immunological-Societies (IUIS), PEOPLES R CHINA, Beijing, 19 October 2019 - 23 October 2019,
    Conference Abstracts | 2019
    Swamy S; Tangye S; Gray P, 2019, 'THE UNWANTED SUPERPOWER', in INTERNAL MEDICINE JOURNAL, WILEY, Vol. 49, pp. 41 - 41,
    Conference Abstracts | 2019
    Yap JY; Gloss B; Batten M; Hsu P; Berglund L; Polizzotto M; Kirk E; Deenick E; Ma C; Tangye S; Phan TG, 2019, 'EVEROLIMUS-INDUCED REMISSION OF KAPOSI'S SARCOMA SECONDARY TO CRYPTIC CTLA4 SPLICING AND HAPLOINSUFFICIENCY', in INTERNAL MEDICINE JOURNAL, WILEY, Vol. 49, pp. 35 - 36,
    Conference Abstracts | 2018
    Tri GP; Tangye S; Wong M; Gray P; Batten M; Goodnow C; Burnett L, 2018, 'CLINICAL IMPACT OF WHOLE GENOME SEQUENCING ON THE DIAGNOSIS AND MANAGEMENT OF PATIENTS WITH PRIMARY IMMUNODEFICIENCY DISEASES - THE CLINICAL IMMUNOGENOMICS RESEARCH CONSORTIUM AUSTRALIA (CIRCA) EXPERIENCE', in INTERNAL MEDICINE JOURNAL, WILEY, Vol. 48, pp. 29 - 29,
    Preprints | 2017
    Guérin A; Kerner G; Marr N; Markle JG; Fenollar F; Wong N; Boughorbel S; Avery DT; Ma CS; Bougarn S; Bouaziz M; Beziat V; Della Mina E; Lazarovt T; Worley L; Nguyen T; Patin E; Deswarte C; Martinez-Barricarte R; Boucherit S; Ayral X; Edouard S; Boisson-Dupuis S; Rattina V; Bigio B; Vogt G; Geissmann F; Quintana-Murci L; Chaussabel D; Tangye SG; Raoult D; Abel L; Bustamante J; Casanova J-L, 2017, IRF4 haploinsufficiency in a family with Whipple’s disease,
    Conference Abstracts | 2017
    Jing H; Abolhassani H; Edwards ESJ; Ikinciogullari KA; Borte S; Buggert M; Du L; Lennikov M; Romano R; Caridha R; Bade S; Zhang Y; Frederiksen J; Fang M; Bal SK; Haskologlu S; Dogu F; Tacyildiz N; Matthews HF; McElwee JJ; Gostick E; Price DA; Palendira U; Aghamohammadi A; Boisson B; Rezaei N; Karlsson A; Lenardo MJ; Casanova J-L; Hammarstrom L; Tangye SG; Pan-Hammarstrom Q; Su HC, 2017, 'COMBINED IMMUNODEFICIENCY AND EPSTEIN-BARR VIRUS-INDUCED B CELL MALIGNANCY IN HUMANS WITH INHERITED CD70 DEFICIENCY', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, WA, Seattle, Vol. 37, pp. 230 - 230, presented at CIS Annual Meeting on Immune Deficiency and Dysregulation North American, WA, Seattle, 23 March 2017 - 26 March 2017,
    Conference Abstracts | 2016
    Bosch B; Dockx S; Tangye SG; Meyts I; Moens L, 2016, 'IPEX ... ARE ALL FEMALE CARRIERS HEALTHY?', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, MA, Boston, Vol. 36, pp. 252 - 252, presented at CIS Annual Meeting on Immune Deficiency and Dysregulation North American Conference, MA, Boston, 14 April 2016 - 17 April 2016,
    Reports | 2016
    Bryant VL; Tangye SG, 2016, The Expanding Spectrum of NFkB1 Deficiency,
    Conference Abstracts | 2016
    Butt D; Chan T; Bourne K; Hermes J; Strasser A; Tangye S; Phan T; Rao VK; Brink R, 2016, 'Rogue germinal center B cells: unconventional lymphocytes released by FAS inactivation that drive IgE and autoantibody production', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 25 - 26, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016,
    Conference Abstracts | 2016
    Edwards ESJ; Cole T; Wong M; Uzel G; Tangye SG, 2016, 'Effect of gain-of-function mutations in PI3 kinase p110d on the phenotype and function of EBV-specific CD8(+) T-cells', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 980 - 981, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016,
    Conference Abstracts | 2016
    Jandl C; Liu SM; Nieto FDCP; Warren J; Hughes WE; Vogelzang A; Webster K; Craig M; Uzel G; Tangye S; Dent A; Vinuesa C; Sprent J; King C, 2016, 'Interleukin-21 limits regulatory T cell populations by modulating responsiveness to Interleukin-2', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 102 - 102, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016,
    Conference Abstracts | 2016
    Kane A; Lau A; Brink R; Tangye S; Deenick E, 2016, 'STAT3 is a critical B-cell intrinsic regulator of functional antibody responses and IgE production', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 849 - 849, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016,
    Reports | 2016
    Ma CS; Tangye SG, 2016, Immunology: Cytotoxic T cells that escape exhaustion,
    Conference Abstracts | 2016
    Martinez-Barricarte R; Aytekin C; Markle J; Kong X-F; Fleckenstein B; Tangye SG; van de Vosse E; Boisson-Dupuis S; Bustamante J; Casanova J-L, 2016, 'INHERITED IL-12R beta 2 DEFICIENCY CAUSES MYCOBACTERIAL SUSCEPTIBILITY', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, MA, Boston, Vol. 36, pp. 270 - 270, presented at CIS Annual Meeting on Immune Deficiency and Dysregulation North American Conference, MA, Boston, 14 April 2016 - 17 April 2016,
    Conference Abstracts | 2016
    Martinez-Barricarte R; Kong X-F; Kennedy J; Lazarov T; Deenick E; Ma C; Mele F; Trouillet C; Bousfiha A; Aytekin C; Picard C; Salem S; Langlais D; Lasseau T; Migaud M; Abel L; Boisson-Dupuis S; Hambleton S; B S; Geissmann F; Tangye S; Sallusto F; Bustamante J; Gros P; Casanova J-L, 2016, 'Mycobacterial disease and myeloid dendritic cells defects in patients with SPPL2a deficiency', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 777 - 778, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016,
    Conference Abstracts | 2016
    Nguyen A; Moran I; Tanaka M; Tangye S; Brink R; Phan T, 2016, 'Dynamic changes in gene regulatory networks control subcapsular sinus macrophage fate and function', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 430 - 430, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016,
    Conference Abstracts | 2016
    Pelham SJ; Lenthall H; Deenick EK; Tangye SG, 2016, 'Mutations underlying autosomal dominant hyper-IgE syndrome impair distinct stages of STAT3 signaling', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 139 - 140, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016,
    Conference Abstracts | 2016
    Pillay BA; Ma CS; Casanova JL; Uzel G; Tangye SG, 2016, 'Using immunodeficiency patient cells in in vitro cultures to provide insight into T-helper cell differentiation', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 988 - 989, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016,
    Conference Abstracts | 2016
    Suan D; Krautler N; Maag J; Butt D; Wood K; Hermes J; Priestley D; Statham A; Elliott M; Marcel D; Basten A; Tangye S; Brink R, 2016, 'Memory B cells develop from low-affinity clones in the germinal center light zone and are identified by CCR6 expression in mice and humans', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 1132 - 1133, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016,
    Conference Abstracts | 2016
    Tangye S, 2016, 'Intrinsic functional defects in human lymphocytes: insights into disease pathogenesis of primary immunodeficiencies', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 1000 - 1000, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016,
    Conference Abstracts | 2016
    Tangye SG, 2016, 'DEFECTS IN HUMAN B-CELL DEVELOPMENT AND DIFFERENTIATION DUE TO DISEASE-CAUSING MUTATIONS IN THE PI3K PATHWAY', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Boston, MA, Vol. 36, pp. 298 - 299, presented at CIS Annual Meeting on Immune Deficiency and Dysregulation North American Conference, Boston, MA, 14 April 2016 - 17 April 2016,
    Reports | 2016
    Tangye SG, 2016, Genetic cause of immune dysregulation one gene or two?,
    Conference Abstracts | 2016
    Vijayan D; Redzwan MN; Avery D; Wirasinha R; Brink R; Walters G; Adelstein S; Kobayashi M; Gray P; Elliott M; King C; Vinuesa C; Ghilardi N; Ma C; Tangye S; Batten M, 2016, 'IL-27 directly influences germinal center B cell development via STAT1', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 1082 - 1082, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016,
    Conference Abstracts | 2016
    Woon H; Braun A; Li J; Smith C; Edwards J; Sierro F; Feng C; Khanna R; Elliot M; Tangye S; Rickinson A; Gebhardt T; Britton W; Palendira M, 2016, 'IL-15 and TGF-beta promote the selective retention of virus-specific resident memory T cells in human lymphoid organs', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, Vol. 46, pp. 57 - 57, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016,
    Conference Abstracts | 2015
    Markle J; Okada S; Deenick E; Mele F; Averbuch D; Lagos M; Gonzalez M; Alzahrani M; Soudais C; Henderson L; Deswarte C; Jabot-Hanin F; Martinez-Barricarte R; Itan Y; Boisson B; Cooper A; Picard C; Abel L; Notarangelo L; Boisson-Dupuis S; Puel A; Sallusto F; Bustamante J; Tangye S; Casanova J-L, 2015, 'Impairment of IL-17A/F Immunity to Candida and IFN-g Immunity to Mycobacterium in Patients with RORC Deficiency', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, ARGENTINA, Buenos Aires, Vol. 35, pp. S13 - S14, presented at 4th Meeting of the Latin-American-Society-for-Immunodeficiencies (LASID), ARGENTINA, Buenos Aires, 18 November 2015 - 21 November 2015,
    Conference Abstracts | 2015
    Williams KW; Edwards E; Stoddard JL; Martinez B; Chen CC; Agharahimi A; Hussey AA; Niemala JE; Holland SM; Tangye SG; Uzel G, 2015, 'PRELIMINARY DATA FOR mTOR INHIBITOR TREATMENT IN PATIENTS WITH OF GAIN-OF-FUNCTION MUTATIONS IN PIK3CD', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, TX, Houston, Vol. 35, pp. 314 - 315, presented at North American Annual Conference of the Clinical-Immunology-Society (CIS) on Immune Deficiency and Dysregulation, TX, Houston, 09 April 2015 - 12 April 2015,
    Conference Papers | 2014
    Barricarte RM; Aytekin C; Markle J; Kong XF; Fleckenstein B; Tangye S; van de Vosse E; Boisson-Dupuis S; Bustamante J; Casanova JL, 2014, 'Inherited IL-12R?2 Complete Deficiency Predisposes to BCG Disease and Tuberculosis', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, CZECH REPUBLIC, Prague, pp. S253 - S254, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, CZECH REPUBLIC, Prague, 29 October 2014 - 01 November 2014,
    Conference Papers | 2014
    Deenick EK; Ives ML; Wilson RP; Uzel G; Tangye SG, 2014, 'The Role of STAT3 in the Differentiation and Function of Unconventional T Cells', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, CZECH REPUBLIC, Prague, pp. S441 - S441, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, CZECH REPUBLIC, Prague, 29 October 2014 - 01 November 2014,
    Conference Abstracts | 2014
    Frith K; O'Brien T; Tangye S; Sutton R; Ziegler J; Gray P, 2014, 'XLP-Associated Cerebral Vasculitis Successfully Treated with Bone Marrow Transplant', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Prague, CZECH REPUBLIC, Vol. 34, pp. S241 - S241, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, Prague, CZECH REPUBLIC, 29 October 2014 - 01 November 2014,
    Conference Abstracts | 2014
    Gray P; Walsh C; Zhu Y; Elakis G; Mullan G; Lo W; Lee E; Cowley M; Dinger M; Buckley M; Ziegler J; Tangye S; Roscioli T, 2014, 'Extrapulmonary Non-Tuberculous Mycobacterial Infection in a Child with Autosomal Dominant Hyper IgE Syndrome', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, CZECH REPUBLIC, Prague, Vol. 34, pp. S499 - S500, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, CZECH REPUBLIC, Prague, 29 October 2014 - 01 November 2014,
    Conference Papers | 2014
    Hsu P; Wong N; Avery DT; Torpy J; Gray P; Fulcher DA; Uzel G; Williams A; Wong M; Campbell D; Tangye SG, 2014, 'RARE STAT1 GOF MUTATION IN DNA BINDING DOMAIN CAUSING MILD CMC', in INTERNAL MEDICINE JOURNAL, WILEY-BLACKWELL, pp. 5 - 5,
    Conference Papers | 2014
    Hsu P; Wong N; Avery DT; Torpy J; Gray PE; Fulcher DA; Uzel G; Williams A; Wong M; Campbell DE; Tangye SG, 2014, 'Rare STAT1 GOF Mutation in Dna Binding Domain Causing Mild CMC', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, CZECH REPUBLIC, Prague, pp. S451 - S451, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, CZECH REPUBLIC, Prague, 29 October 2014 - 01 November 2014,
    Conference Papers | 2014
    Jackson CC; Byun M; Ma CS; Akcay A; Pedergnana V; Palendira U; Myoung J; Avery DT; Liu Y; Abhyankar A; Lorenzo L; Schmidt M; Lim HK; Cassar O; Migaud M; Rozenberg F; Canpolat N; Aydogan G; Fleckenstein B; Bustamante J; Picard C; Gessain A; Jouanguy E; Cesarman E; Olivier M; Gros P; Abel L; Croft M; Tangye SG; Casanova J-L, 2014, 'INHERITED HUMAN OX40 DEFICIENCY UNDERLYING CLASSIC KAPOSI SARCOMA OF CHILDHOOD', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, pp. 702 - 703,
    Conference Papers | 2014
    Jackson CC; Byun M; Ma CS; Akcay A; Pedergnana V; Palendira U; Myoung J; Avery DT; Liu Y; Abhyankar A; Lorenzo L; Schmidt M; Lim HK; Cassar O; Migaud M; Rozenberg F; Canpolat N; Aydogan G; Fleckenstein B; Bustamante J; Picard C; Gessain A; Jouanguy E; Cesarman E; Olivier M; Gros P; Abel L; Croft M; Tangye SG; Casanova J-L, 2014, 'INHERITED HUMAN OX40 DEFICIENCY UNDERLYING CLASSIC KAPOSI SARCOMA OF CHILDHOOD', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, TURKEY, Antalya, pp. 702 - 703, presented at 100th J Project Meeting, TURKEY, Antalya, 12 March 2014 - 14 March 2014,
    Conference Papers | 2014
    Kong XF; Lasseau T; Trouillet C; Bousfiha A; Aytekin C; Deswarte C; Boisson-Dupuis S; Vogt G; Gros P; Tangye S; Geissmann F; Bustamante J; Casanova JL, 2014, 'A New Genetic Disorder Predispose Mendelian Susceptibility to Mycobacterial Diseases', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, CZECH REPUBLIC, Prague, pp. S140 - S141, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, CZECH REPUBLIC, Prague, 29 October 2014 - 01 November 2014,
    Conference Papers | 2014
    Ma CS; Wong N; Avery DT; Torpy J; Stoddard JL; Kobayashi M; Deenick EK; Casanova JL; Uzel G; Tangye SG, 2014, 'Determining the Molecular Requirements for Generating Human T Follicular Helper (Tfh) Cells', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, CZECH REPUBLIC, Prague, pp. S458 - S459, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, CZECH REPUBLIC, Prague, 29 October 2014 - 01 November 2014,
    Conference Papers | 2014
    Markle J; Okada S; Deenick E; Mele F; Wong N; Ma CS; Soudais C; Averbuch D; Alzahrani M; Lagos M; Gonzalez M; Martinez-Baricarte R; Okada C; Migaud M; Itan Y; Picard C; Lantz O; Abel L; Engelhard D; Al-Muhsen S; Sallusto F; Boisson-Dupuis S; Puel A; Bustamante J; Tange S; Casanova JL, 2014, 'Dual Impairment of IL-17 and IFN-G Immunity Cause Infections by Candida and Mycobacterium in Humans with RORC Deficiency', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, CZECH REPUBLIC, Prague, pp. S485 - S486, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies (ESID), CZECH REPUBLIC, Prague, 29 October 2014 - 01 November 2014,
    Conference Papers | 2014
    Martinez-Barricarte R; Aytekin C; Markle J; Knog XF; Fleckenstein B; Tangye S; van de Vosse E; Boisson-Dupuis S; Bustamante J; Casanova JL, 2014, 'Inherited IL-12R beta 2 Complete Deficiency Predisposes to BCG Disease and Tuberculosis', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, CZECH REPUBLIC, Prague, pp. S488 - S488, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, CZECH REPUBLIC, Prague, 29 October 2014 - 01 November 2014,
    Conference Papers | 2014
    Schwartzberg P; Cannons J; Zhao P; Reilley J; Kapnick S; Tangye S; Uzel G, 2014, 'Defects in CD8 Cytolysis in Immunodeficiencies with Impaired EBV Clearance', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, CZECH REPUBLIC, Prague, pp. S491 - S492, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, CZECH REPUBLIC, Prague, 29 October 2014 - 01 November 2014,
    Conference Papers | 2014
    Stoddard JL; Hsu AP; Hussey AA; Agharahimi A; Holland SM; Fleisher TA; Tangye SG; Uzel G, 2014, 'Beyond T, B, and NK Flow: An Extended Analytical Panel for the Flow Cytometric Evaluation of Primary Immune Deficiencies', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, MD, Baltimore, pp. 366 - 366, presented at Primary Immune Deficiency Diseases North American Conference of the Clinical-Immunology-Society (CIS), MD, Baltimore, 10 April 2014 - 13 April 2014,
    Conference Papers | 2014
    Tangye SG; Stoddard JL; Ma CS; Wong N; Hsu AP; Fleisher TA; Pittaluga S; Holland SM; Uzel G, 2014, 'Primary Immune Deficiencies Help to Reveal Molecular Requirements for Human T Follicular Helper Cells', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, MD, Baltimore, pp. 360 - 360, presented at Primary Immune Deficiency Diseases North American Conference of the Clinical-Immunology-Society (CIS), MD, Baltimore, 10 April 2014 - 13 April 2014,
    Conference Papers | 2014
    Uzel G; Kuehn HS; Weiming Q; Lo B; Deenick EK; Niemela JE; Avery DT; Schickel JN; Tran DQ; Stoddard J; Zhang Y; Frucht DM; Rao KV; Su HC; Notarangelo LD; Olivier KN; McElwee J; Pittaluga S; Oliveira JB; Meffre E; Fleisher TA; Holland SM; Tangye SG; Lenardo MJ, 2014, 'Human CTLA4 Haploinsufficiency Causes Severe Immune Dysregulation', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, CZECH REPUBLIC, Prague, pp. S144 - S145, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, CZECH REPUBLIC, Prague, 29 October 2014 - 01 November 2014,
    Conference Papers | 2014
    Uzel G; Stoddard J; Martinez B; Agharahimi A; Hussey AA; Folio LR; Pittaluga S; Fleisher TA; Tangye SG; Holland SM, 2014, 'A Short-Term Treatment Summary Using M-TOR Inhibitors in Patients with Germline PIK3CD Mutations: Prospects for Future', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, CZECH REPUBLIC, Prague, pp. S164 - S164, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, CZECH REPUBLIC, Prague, 29 October 2014 - 01 November 2014,
    Conference Papers | 2013
    Redzwan NM; Vijayan D; Ma C; Tangye S; Brink R; Vinuesa C; Batten M, 2013, 'IL-27 signals to both B and T cells support germinal center function and the development of GC-driven lupus', in CYTOKINE, ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, CA, San Francisco, pp. 292 - 292, presented at Annual Joint Conference of the International-Cytokine-Society and the International-Society-for-Interferon-and-Cytokine-Research, CA, San Francisco, 29 September 2013 - 03 October 2013,
    Conference Papers | 2012
    Berglund LJ; Cook M; Wong M; Fulcher D; Adelstein S; Arkwright P; Ziegler J; Smart J; Tangye SG, 2012, 'IL-2 ENHANCES THE EFFECTS OF IL-21 ON HUMORAL IMMUNE RESPONSES IN HUMANS', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, ITALY, Florence, pp. 280 - 280, presented at 15th Biennial Meeting European-Society-for-Immunodeficiency (ESID), ITALY, Florence, 03 October 2012 - 06 October 2012,
    Conference Papers | 2012
    Byun M; Ma CS; Akcay A; Canpolat N; Aydogan G; Abhyankar A; Pedergnana V; Lorenzo L; Schmidt M; Mueller-Fleckenstein I; Picard C; Lim H-K; Migaud M; Bustamante J; Gessain A; Plancoulaine S; Cesarman E; Croft M; Abel L; Jouanguy E; Tangye SG; Casanova J-L, 2012, 'A NEW PRIMARY IMMUNODEFICIENCY AFFECTING T CELLS IN A PATIENT WITH KAPOSI SARCOMA AND LEISHMANIASIS', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, ITALY, Florence, pp. 384 - 384, presented at 15th Biennial Meeting European-Society-for-Immunodeficiency (ESID), ITALY, Florence, 03 October 2012 - 06 October 2012,
    Conference Papers | 2012
    Ives M; Ma C; Palendira U; French MA; Choo S; Smart J; Wong M; Arkwright PD; Fulcher DA; Cook MC; Casanova J-L; Tangye SG; Deenick EK, 2012, 'PRIMARY IMMUNE DEFICIENCIES REVEAL THE ROLE OF STAT1 AND STAT3 IN THE ACTIVATION AND DIFFERENTIATION OF HUMAN CD8(+) T CELLS', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, ITALY, Florence, pp. 311 - 312, presented at 15th Biennial Meeting European-Society-for-Immunodeficiency (ESID), ITALY, Florence, 03 October 2012 - 06 October 2012,
    Conference Papers | 2012
    Recher M; Deenick E; Al-Herz W; Frugoni F; Lee Y; Delmonte OM; Giliani S; Walter JE; Berger CT; Nobre R; Roscioli T; Buckley MF; Ziegler JB; Wong M; Megarbane A; Chouery E; Lefranc G; Hess C; Tangye S; Notarangelo LD; Bloch D, 2012, 'SP110 REGULATES NUCLEAR ORPHAN RECEPTOR NUR77-DRIVEN APOPTOSIS IN T CELLS', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, ITALY, Florence, pp. 20 - 21, presented at 15th Biennial Meeting of the European-Society-for-Primary-Immunodeficiency (ESID), ITALY, Florence, 03 October 2012 - 06 October 2012,
    Conference Papers | 2008
    Chagantl S; Ma C; Bell A; Croom-Carter D; Hislop A; Tangye SG; Rickinson A, 2008, 'High level EBV persistence in the IgM + IgD+CD27+B cell subset in patients with X-linked lymphoproliferative disease lacking isotype-switched memory B cells', in British Journal of Haematology, Blackwell Publishing Ltd, Oxford, England, pp. 19 - 20, presented at Abstracts of the British Society of Haematology 48th Annual Scientific Meeting, incorporating the 6th Bi-Annual I-BFM Leukaemia Symposium
    Conference Papers | 2007
    Chaganti S; Ma C; Bell A; Croom-Carter D; Hislop A; Tangye S; Rickinson A, 2007, 'High level EBV persistence in the IgM(+) IgD(+) CD27(+) B cell subset in patients with X-linked lymphoproliferative disease lacking isotype-switched memory B cells', in BLOOD, AMER SOC HEMATOLOGY, GA, Atlanta, pp. 675A - 675A, presented at 49th Annual Meeting of the American-Society-of-Hematology, GA, Atlanta, 08 December 2007 - 11 December 2007,
    Preprints |
    Masle-Farquhar E; Peters TJ; Jackson KJL; Singh M; Ma CS; Suan D; Uzel G; Chua I; Leiding JW; Heiskanen K; Preece K; Kainulainen L; O’Sullivan M; Cooper MA; Seppänen MRJ; Mustjoki S; Brothers S; Vogel TP; Brink R; Tangye SG; Reed JH; Goodnow CC, Overactive STAT3 Drives Accumulation of Disease-Associated CD21 <sup>low</sup> B Cells, ,