Associate Professor Matthew Baker
DPhil, Oxford University.
BSc (Hons), Australian National University.
Dr Matt Baker is a Scientia Associate Professor in the School of Biotechnology and Biomolecular Sciences at the University of New South Wales.
Matt completed his DPhil in Physics at Oxford University as a John Monash Scholar studying the bacterial flagellar motor that makes nearly all bacteria swim. Subsequently Matt investigated protein transport in Oxford's Chemistry Research Laboratory and in the Department of Biochemistry. Upon his return to Australia, Matt focused primarily on how simple subunit interactions govern assembly of complex architectures, including the rotor () and filament () of the bacterial flagellar motor. The next question is how this complexity emerged. To begin addressing this, Matt's nascent group at UNSW looks at how ion selectivity changes using directed evolution (, ) to examine the evolutionary landscape that constrains the adaptation of the motor (). We then use this knowledge to examine potential applications of the flagellar motor elsewhere (, ).
Our group also investigates that in synthetic lipid bilayers (). These are essential at all scales of life, in bacteria to respond to osmotic shock and in mammals in the sense of touch and hearing and are involved in cancer progression and arthritis. In collaboration with , we probe membrane dynamics and interactions using novel DNA nanotechnology (Nanoscale 2019, ), with the ultimate goal to control membrane communication using de novo DNA nanotechnology.
Matt also has a love of radio: he was a Top 5 Under 40 Scientist in Residence at the ABC in 2015 and has continued since then asÌýtheÌýregular science presenter on , broadcast on ABC Local across Australia, and by producingÌýcontent for the , , Saturday Extra and on ABC's Radio National. He is currently a 'Resident Scientist' on - Sydney's First Nations Radio station and also on 's flagship weekend breakfast show with Kim Hill. He also has applied his data skills to journalism; he was Australia's inaugural in 2016 when he was embedded at the Sydney Morning Herald. Matt is active in Australia-China relations and has been an delegate and panel chair at the since 2015.
Currently our group consists of 5 PhD students, 4 postdocs and 2 Hons students working in roughly a fifty-fifty split across flagellar and in vitro lipid/DNA projects. At any stage we welcome applications for PhDs and Hons students. We have recently by the , so applicants interested in postdoctoral opportunities should get in touch.
A collection of links can be found on Matt's .
Matt teaches in the School of Biotechnology and Biomolecular Science. He is co-convener of 3rd Year synthetic biology (BABS3200) focusing on DNA nanotechnology and directed evolution approaches, and he gives guest lectures into 1st Year Genes, 2nd Year Microbiology, 3rd Year Environmental Microbiology and 3rd Year Microbial Genetics.
- Publications
- Media
- Grants
- Awards
- Research Activities
- Engagement
- Teaching and Supervision
- International Funding:
- Human Frontiers Science Programme RGY0072.
- US Navy Office of Naval Research Program Grant
- Category 1 Funding:
- Australian Research Council DP190100497.
- Australian Research Council DP210101892.
- Industry Funding:
- CSIRO Synthetic Biology Platform Project Grant 2018-2021.
- Medical Advances Without Animals – 2020-2021.
2023 Promoted to Associate Professor
2021-24 Elected Councillor, International Union of Pure and Applied Biophysics
2020-21 President, Australian Society of Biophysics.
2019 promoted to Senior Lecturer.
2018Ìý UNSW Faculty of Science – Dean’s Award for Excellence in Science Communication
2018Ìý Scientia Research Fellowship – UNSW Fellowship
2017Ìý Young 'Tall Poppy' Award, NSW – Australian Instute of Policy and Science
2016Ìý Google News Lab Fellowship – Sole Australian Fellow.
2015Ìý Australia-China Youth Dialogue Delegate
2015Ìý Top 5 Under 40 Winner – ABC/UNSW fellowship to ‘discover Australia’s new generation of science thinkers’
2015Ìý Robert M. Macnab Memorial Travel Award to speak at BLAST XIII in Tucson, Arizona
2009:Ìý Nicholas Kurti Prize for Best 3rd Year DPhil Student Physics, University of Oxford.
2009: Nesta Famelab UK Finalist ().
2005-2009ÌýÌý John Monash Scholar (). PhD Fellowship.
2001-2004ÌýÌý ANU National Undergraduate Scholarship.
For more up to date biographies of my team and our current research projects please consult my lab website.
Some of our recent research has featured on the UNSW newsroom:
I also have written editorials (at the and ) in the past on the role of the flagellar motor in
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My Research Supervision
Vibhuti Nandel
Janelle Ramos
James Gaston
Jyoti Gurung
Md Imtiazul Islam