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Professor Georgina Hold

Professor Georgina Hold

Professor

INSTITUTION AND LOCATION

DEGREE

(if applicable)

Completion Date

MM/YYYY

FIELD OF STUDY

University of Surrey, UK

University of Glasgow, UK

BSc (Hons)

PhD

07/1995

12/1999

Biochemistry/Toxicology

Molecular Microbial Ecology

Medicine & Health
School of Clinical Medicine

Professor Georgina Hold is aProfessor of Gut Microbiologyat the St George and Sutherland Clinical School, UNSW Australia.

Research Interests:

Understanding the impact of gastrointestinal microbes on human health and disease. In particular understanding the interactions between resident microbes and their host and how changes in the microbiota impact on human health. Developing greater understanding in this area allows us to further appreciate the contribution that gut microbes play in diseases and potentially develop therapeutic strategies to maintain and restore health. My lab has an internationally renowned reputation for microbiome analysis. This has been achieved by a) developing robust protocols for collecting and processing the most clinically relevant samples, and b) ensuring the science is clinically driven. The main challenges in gut microbiome research relate to defining the metabolic capabilities of the gut microbiota, the effect of therapeutic regimens on the gut microbiota and ultimately identifying how to manipulate these factors to promote/maintain health. This requires multi-disciplinary research strategies harnessing clinicians, microbiologists, nutritionists, epidemiologists, bioinformaticians and also public health analysts. To achieve this we collaborate with groups all over the world to ensure we bring together the skills sets required to address multi-faceted research questions.

Broad Areas of Research:

Inflammatory bowel disease

Gastrointestinal malignancy including liver cancer

Host/Microbial interactions

Microbial therapeutics

Qualifications:
BSc (Hons) in Biochemistry/Toxicology (1995)
PhD (1999)
Fulbright Scholar (2014-2015)

Senior Fellow Higher Education Authority (SFHEA UK)

Society Memberships & Professional Activities:

Member of the British Society of Gastroenterology
Member of the Scottish Society of Gastroenterology

Member of the Scottish Paediatric Gastroenterology, Hepatology and Nutrition Society

Member of the Society of General Microbiology (UK)

Member of the Society for Applied Microbiology (UK)

Visiting Scholar: Harvard T.H. Chan School of Public Health, Boston, USA; term July 2014 - 2021.

Honorary Academic Appointment, Aberdeen University;2017 - 2021

Honorary Academic Appointment, University College London;2014 - 2020

Specific Research Keywords:
Inflammatory bowel disease, colorectal cancer, gut microbiota, host microbial interactions, Campylobacter, microbial therapeutics

Phone
+61 2 91131855
Location
St George & Sutherland Clinical School Level 2 Pitney Building St George Hospital NSW 2217
  • Book Chapters | 2022
    Hold GL; Rokkas T, 2022, '2.12 - Changes in Gut Microbiota Due to Gastrointestinal Surgery', in Comprehensive Gut Microbiota, Elsevier, pp. 139 - 144,
    Book Chapters | 2018
    Clegg F; Berry SH; Hansen R; Hold GL, 2018, 'Molecular analysis of the microbiome in colorectal cancer', in Colorectal Cancer, Springer, pp. 139 - 153,
    Book Chapters | 2016
    McLean MH; Nicoll R; Saw C; Hold GL; El-Omar EM, 2016, 'Influence of host gene polymorphisms on development of gastroduodenal diseases', in Helicobacter pylori Research: From Bench to Bedside, pp. 339 - 362,
    Book Chapters | 2011
    Hold GL; Bryant CE, 2011, 'The Molecular Basis of Lipid A and Toll-Like Receptor 4 Interactions', in Knirel YA; Valvano MA (ed.), BACTERIAL LIPOPOLYSACCHARIDES: STRUCTURE, CHEMICAL SYNTHESIS, BIOGENESIS AND INTERACTION WITH HOST CELLS, SPRINGER-VERLAG WIEN, pp. 371 - 387,
  • Journal articles | 2024
    Ariaee A; Koentgen S; Wardill HR; Hold GL; Prestidge CA; Armstrong HK; Joyce P, 2024, 'Prebiotic selection influencing inflammatory bowel disease treatment outcomes: a review of the preclinical and clinical evidence', eGastroenterology, 2, pp. e100055 - e100055,
    Journal articles | 2024
    Gemmell MR; Jayawardana T; Koentgen S; Brooks E; Kennedy N; Berry S; Lees C; Hold GL, 2024, 'Optimised human stool sample collection for multi-omic microbiota analysis', Scientific Reports, 14,
    Journal articles | 2024
    Katsoudas N; Tavakoli P; Wu N; Shapiro A; Leach ST; Williams AJ; Paramsothy R; Ghaly S; Connor SJ; Samocha-Bonet D; Lambert K; Hold GL, 2024, 'Dietary Emulsifier Exposure in People with Inflammatory Bowel Disease Compared with Healthy Controls: Is There a Cause for Concern?', Inflammatory Bowel Diseases, 30, pp. 1241 - 1250,
    Journal articles | 2024
    Little RD; McKenzie J; Srinivasan A; Hilley P; Gilmore RB; Chee D; Sandhu M; Saitta D; Chow E; Thin L; Walker GJ; Moore GT; Lynch K; Andrews J; An YK; Bryant RV; Connor SJ; Garg M; Wright EK; Hold G; Segal JP; Boussioutas A; De Cruz P; Ward MG; Sparrow MP, 2024, 'Switching from Dose-Intensified intravenous to SubCutaneoUS infliximab in Inflammatory Bowel Disease (DISCUS-IBD): protocol for a multicentre randomised controlled trial', BMJ Open, 14,
    Journal articles | 2024
    Noble A; Adams A; Nowak J; Cheng G; Nayak K; Quinn A; Kristiansen M; Kalla R; Ventham NT; Giachero F; Jayamanne C; Hansen R; Hold GL; El-Omar E; Croft NM; Wilson D; Beattie RM; Ashton JJ; Zilbauer M; Ennis S; Uhlig HH; Satsangi J, 2024, 'The circulating methylome in childhood-onset inflammatory bowel disease.', J Crohns Colitis,
    Journal articles | 2024
    Rimmer P; Scott G; Quraishi MN; Hazel K; Cooney R; Zhang F; Hold GL; Gordon M; Iqbal T; Hansen R, 2024, 'Sa1887 IS DIVERSITY IMPORTANT IN THE GUT MICROBIOME AT IBD ONSET? A SYSTEMATIC REVIEW OF THE LITERATURE AND META-ANALYSIS OF ALPHA-DIVERSITY DATA', Gastroenterology, 166,
    Journal articles | 2023
    Baumdick ME; Niehrs A; Degenhardt F; Schwerk M; Hinrichs O; Jordan-Paiz A; Padoan B; Wegner LHM; Schloer S; Zecher BF; Malsy J; Joshi VR; Illig C; Schröder-Schwarz J; Möller KJ; Akar A; Flemming C; Felix ; Flomm ; Flosbach M; Jäger J; Jeromin N; Jung J; Ohms M; Reinshagen K; Rische J; Sagebiel A; Sandfort D; Steinert F; Tomuschat C; Wesche J; Martin MP; Yuki Y; Ozawa M; Sauter J; Schmidt AH; Perez D; Giannou AD; Carrington M; Davis RS; Schumacher U; Sauter G; Huber S; Puelles VG; Melling N; Franke A; Shifteh Abedian ; Abraham C; Achkar JP; Ahmad T; Alberts R; Alizadeh B; Amininejad L; Ananthakrishnan AN; Andersen V; Anderson CA; Andrews JM; Annese V; Aumais G; Baidoo L; Baldassano RN; Bampton PA; Barclay M; Barrett JC; Bethge J; Bewshea C; Bis JC; Bitton A; BK T; Boucher G; Brain O; Brand S; Brant SR; Cheon JH; Chew A; Cho JH; Cleynen I; Cohain A; Cooney R; Croft A; Daly MJ; D'Amato M; Danese S; Daryani NE; Datta LW; Denapiene G; Denson LA; Devaney KL; Dewit O; D'Inca R; Drummond HE; Dubinsky M; Duerr RH; Edwards C; Ellinghaus D; Ellul P; Esaki M; Essers J; Ferguson LR; Festen EA, 2023, 'HLA-DP on Epithelial Cells Enables Tissue Damage by NKp44+ Natural Killer Cells in Ulcerative Colitis', Gastroenterology, 165, pp. 946 - 962.e13,
    Journal articles | 2023
    Mah C; Jayawardana T; Leong G; Koentgen S; Lemberg D; Connor SJ; Rokkas T; Grimm MC; Leach ST; Hold GL, 2023, 'Assessing the Relationship between the Gut Microbiota and Inflammatory Bowel Disease Therapeutics: A Systematic Review', Pathogens, 12,
    Journal articles | 2023
    Oosterlinck B; Arras W; De Man J; Geboes K; De Schepper HU; Peeters M; Lebeer S; Skieceviciene J; Hold GL; Kupcinskas J; Link A; De Winter BY; Smet A, 2023, 'Sa1865 MUCIN-MICROBIOME SIGNATURES SHAPE THE TUMOUR MICROENVIRONMENT IN GASTRIC CANCER', Gastroenterology, 164, pp. S - 468,
    Journal articles | 2023
    Oosterlinck B; Ceuleers H; Arras W; De Man JG; Geboes K; De Schepper H; Peeters M; Lebeer S; Skieceviciene J; Hold GL; Kupcinskas J; Link A; De Winter BY; Smet A, 2023, 'Mucin-microbiome signatures shape the tumor microenvironment in gastric cancer', Microbiome, 11, pp. 86,
    Journal articles | 2023
    Rokkas T; Hold GL, 2023, 'A systematic review, pairwise meta-analysis and network meta-analysis of randomized controlled trials exploring the role of fecal microbiota transplantation in irritable bowel syndrome', European Journal of Gastroenterology and Hepatology, 35, pp. 471 - 479,
    Journal articles | 2023
    Zhang F; Gia A; Chen G; Gong L; Behary J; Hold GL; Zekry A; Tang X; Sun Y; El-Omar E; Jiang XT, 2023, 'Critical Assessment of Whole Genome and Viral Enrichment Shotgun Metagenome on the Characterization of Stool Total Virome in Hepatocellular Carcinoma Patients', Viruses, 15, pp. 53,
    Journal articles | 2022
    Amorim N; McGovern E; Raposo A; Khatiwada S; Shen S; Koentgen S; Hold G; Behary J; El-Omar E; Zekry A, 2022, 'Refining a Protocol for Faecal Microbiota Engraftment in Animal Models After Successful Antibiotic-Induced Gut Decontamination', Frontiers in Medicine, 9,
    Journal articles | 2022
    Breugelmans T; Oosterlinck B; Arras W; Ceuleers H; De Man J; Hold GL; De Winter BY; Smet A, 2022, 'The role of mucins in gastrointestinal barrier function during health and disease', The Lancet Gastroenterology and Hepatology, 7, pp. 455 - 471,
    Journal articles | 2022
    Carserides C; Smith K; Zinicola M; Kumar A; Swedrowska M; Scala C; Cameron G; Riches Z; Iannelli F; Pozzi G; Hold GL; Forbes B; Kelly C; Hijazi K, 2022, 'Comprehensive Study of Antiretroviral Drug Permeability at the Cervicovaginal Mucosa via an In Vitro Model', Pharmaceutics, 14,
    Journal articles | 2022
    Gulliver EL; Young RB; Chonwerawong M; D'Adamo GL; Thomason T; Widdop JT; Rutten EL; Rossetto Marcelino V; Bryant RV; Costello SP; O'Brien CL; Hold GL; Giles EM; Forster SC, 2022, 'Review article: the future of microbiome-based therapeutics', Alimentary Pharmacology and Therapeutics, 56, pp. 192 - 208,
    Journal articles | 2022
    James KR; Elmentaite R; Teichmann SA; Hold GL, 2022, 'Correction to: Redefining intestinal immunity with single-cell transcriptomics (Mucosal Immunology, (2021), 10.1038/s41385-021-00470-y)', Mucosal Immunology, 15, pp. 526 - 526,
    Journal articles | 2022
    James KR; Elmentaite R; Teichmann SA; Hold GL, 2022, 'Redefining intestinal immunity with single-cell transcriptomics', Mucosal Immunology, 15, pp. 531 - 541,
    Journal articles | 2022
    Little RD; Ward MG; Wright E; Jois AJ; Boussioutas A; Hold GL; Gibson PR; Sparrow MP, 2022, 'Therapeutic Drug Monitoring of Subcutaneous Infliximab in Inflammatory Bowel Disease—Understanding Pharmacokinetics and Exposure Response Relationships in a New Era of Subcutaneous Biologics', Journal of Clinical Medicine, 11,
    Journal articles | 2022
    O'Donnell M; Teasdale S; Chua X-Y; Hardman J; Wu N; Curtis J; Samaras K; Bolton P; Morris M; Shannon-Weickert C; Purves-Tyson T; El-Assaad F; Jiang X; Hold G; El-Omar E; Wu N, 2022, 'The role of the microbiome in the metabolic health of people with schizophrenia and related psychoses: cross-sectional and pre-post lifestyle intervention analyses', Pathogens, 11, pp. 1279,
    Journal articles | 2022
    Shaw S; Berry S; Thomson J; Murray GI; El-Omar E; Hold GL, 2022, 'Gut Mucosal Microbiome Signatures of Colorectal Cancer Differ According to BMI Status', Frontiers in Medicine, 8,
    Journal articles | 2022
    Smet A; Kupcinskas J; Link A; Hold GL; Bornschein J, 2022, 'The Role of Microbiota in Gastrointestinal Cancer and Cancer Treatment: Chance or Curse?', Cellular and Molecular Gastroenterology and Hepatology, 13, pp. 857 - 874,
    Journal articles | 2021
    Bornschein J; Tran-Nguyen T; Fernandez-Esparrach G; Ash S; Balaguer F; Bird-Lieberman EL; Córdova H; Dzerve Z; Fassan M; Leja M; Lyutakov I; Middelburg T; Moreira L; Nakov R; Nieuwenburg SAV; O'Connor A; Realdon S; De Schepper H; Smet A; Spaander MCW; Tolmanis I; Urbonas T; Weigt J; Hold GL; Link A; Kupcinskas J, 2021, 'Biopsy Sampling in Upper Gastrointestinal Endoscopy: A Survey from 10 Tertiary Referral Centres across Europe', Digestive Diseases, 39, pp. 179 - 189,
    Journal articles | 2021
    Hansen R; Bajaj-Elliott M; Hold GL; Gerasimidis K; Iqbal TH; Amos G; Thomas LV; Marchesi JR, 2021, 'Next-generation sequencing as a clinical laboratory tool for describing different microbiotas: An urgent need for future paediatric practice', Archives of Disease in Childhood, 106, pp. 1035,
    Journal articles | 2021
    Keller JJ; Ooijevaar RE; Hvas CL; Terveer EM; Lieberknecht SC; Högenauer C; Arkkila P; Sokol H; Gridnyev O; Mégraud F; Kump PK; Nakov R; Goldenberg SD; Satokari R; Tkatch S; Sanguinetti M; Cammarota G; Dorofeev A; Gubska O; Ianiro G; Mattila E; Arasaradnam RP; Sarin SK; Sood A; Putignani L; Alric L; Baunwall SMD; Kupcinskas J; Link A; Goorhuis AG; Verspaget HW; Ponsioen C; Hold GL; Tilg H; Kassam Z; Kuijper EJ; Gasbarrini A; Mulder CJJ; Williams HRT; Vehreschild MJGT, 2021, 'A standardised model for stool banking for faecal microbiota transplantation: a consensus report from a multidisciplinary UEG working group', United European Gastroenterology Journal, 9, pp. 229 - 247,
    Journal articles | 2021
    Lambert K; Pappas D; Miglioretto C; Javadpour A; Reveley H; Frank L; Grimm MC; Samocha-Bonet D; Hold GL, 2021, 'Systematic review with meta-analysis: dietary intake in adults with inflammatory bowel disease', Alimentary Pharmacology and Therapeutics, 54, pp. 742 - 754,
    Journal articles | 2021
    Mahalhal A; Burkitt MD; Duckworth CA; Hold GL; Campbell BJ; Pritchard DM; Probert CS, 2021, 'Long‐term iron deficiency and dietary iron excess exacerbate acute dextran sodium sulphate‐induced colitis and are associated with significant dysbiosis', International Journal of Molecular Sciences, 22,
    Journal articles | 2021
    Nelson A; Stewart CJ; Kennedy NA; Lodge JK; Tremelling M; Probert CS; Parkes M; Mansfield JC; Smith DL; Hold GL; Lees CW; Bridge SH; Lamb CA, 2021, 'The Impact of NOD2 Genetic Variants on the Gut Mycobiota in Crohn's Disease Patients in Remission and in Individuals without Gastrointestinal Inflammation', Journal of Crohn's and Colitis, 15, pp. 800 - 812,
    Journal articles | 2021
    Williams AJ; Paramsothy R; Wu N; Ghaly S; Leach S; Paramsothy S; Corte C; O'Brien C; Burke C; Wark G; Samocha-Bonet D; Lambert K; Ahlenstiel G; Wasinger V; Dutt S; Pavli P; Grimm M; Lemberg D; Connor S; Leong R; Hold G, 2021, 'Australia IBD Microbiome (AIM) Study: Protocol for a multicentre longitudinal prospective cohort study', BMJ Open, 11,
    Journal articles | 2021
    Wu N; Mah C; Koentgen S; Zhang L; Grimm MC; El-Omar E; Hold GL, 2021, 'Inflammatory bowel disease and the gut microbiota', Proceedings of the Nutrition Society, 80, pp. 424 - 434,
    Journal articles | 2020
    Bezawada N; Phang TH; Hold GL; Hansen R, 2020, 'Autism Spectrum Disorder and the Gut Microbiota in Children: A Systematic Review', Annals of Nutrition and Metabolism, 76, pp. 16 - 29,
    Journal articles | 2020
    Link A; Hold G, 2020, 'First Case of Covid-19 in the United States', The New England journal of medicine, 382, pp. e53,
    Journal articles | 2020
    Ormsby MJ; Johnson SA; Carpena N; Meikle LM; Goldstone RJ; McIntosh A; Wessel HM; Hulme HE; McConnachie CC; Connolly JPR; Roe AJ; Hasson C; Boyd J; Fitzgerald E; Gerasimidis K; Morrison D; Hold GL; Hansen R; Walker D; Smith DGE; Wall DM, 2020, 'Propionic Acid Promotes the Virulent Phenotype of Crohn's Disease-Associated Adherent-Invasive Escherichia coli', Cell Reports, 30, pp. 2297 - 2305.e5,
    Journal articles | 2020
    Rajilic-Stojanovic M; Figueiredo C; Smet A; Hansen R; Kupcinskas J; Rokkas T; Andersen L; Machado JC; Ianiro G; Gasbarrini A; Leja M; Gisbert JP; Hold GL, 2020, 'Systematic review: gastric microbiota in health and disease', Alimentary Pharmacology and Therapeutics, 51, pp. 582 - 602,
    Journal articles | 2020
    Susic D; Davis G; O' Sullivan AJ; McGovern E; Harris K; Roberts LM; Craig ME; Mangos G; Hold GL; El-Omar EM; Henry A; O'Sullivan A, 2020, 'Microbiome Understanding in Maternity Study (MUMS), an Australian prospective longitudinal cohort study of maternal and infant microbiota: study protocol', BMJ open, 10, pp. e040189,
    Journal articles | 2019
    Bond A; Greenwood R; Lewis S; Corfe B; Sarkar S; O’Toole P; Rooney P; Burkitt M; Hold G; Probert C, 2019, 'Volatile organic compounds emitted from faeces as a biomarker for colorectal cancer', Alimentary Pharmacology and Therapeutics, 49, pp. 1005 - 1012,
    Journal articles | 2019
    Gemmell M; Berry S; Mukhopadhya I; Gong L; Hansen R; Hold G, 2019, 'Draft genome sequences of a Campylobacter curvus and three Campylobacter ureolyticus strains isolated from human colonic mucosal tissue', Microbiota in Health and Disease, 1, pp. e148 - e148,
    Journal articles | 2019
    Hold GL; Allen-Vercoe E, 2019, 'Gut microbial biofilm composition and organisation holds the key to CRC', Nature Reviews Gastroenterology and Hepatology, 16, pp. 329 - 330,
    Journal articles | 2019
    Hold GL; Hansen R, 2019, 'Impact of the gastrointestinal microbiome in health and disease: Co-evolution with the host immune system', , 421, pp. 303 - 318,
    Journal articles | 2019
    Hsu T; Gemmell MR; Franzosa EA; Berry S; Mukhopadhya I; Hansen R; Michaud M; Nielsen H; Miller WG; Nielsen H; Bajaj-Elliott M; Huttenhower C; Garrett WS; Hold GL, 2019, 'Comparative genomics and genome biology of Campylobacter showae', Emerging Microbes and Infections, 8, pp. 827 - 840,
    Journal articles | 2019
    Keller JJ; Vehreschild MJGT; Hvas CL; Jorgensen SMD; Kupciskas J; Link A; Mulder CJJ; Goldenberg SD; Arasaradnam R; Sokol H; Gasbarrini A; Hoegenauer C; Terveer EM; Kuijper EJ; Arkkila P; Gasbarrini A; Gridnyev O; Megraud F; Kump PK; Nakov R; Goldenberg SD; Satokari R; Tkatch S; Sanguinetti M; Sokol H; Cammarota G; Dorofeev A; Keller JJ; Hoegenauer C; Gubska O; Ianiro G; Mattila E; Ooijevaar RE; Arasaradnam R; Sarin SK; Sood A; Putignani L; Alric L; Arkkila P; Hvas CL; Jorgensen SMD; Kuijper EJ; Kupciskas J; Link A; Mulder CJJ; Williams HRT; Goorhuis A; Verspaget HW; Terveer EM; Hold GL; Tilg H; Ponsioen CY, 2019, 'Stool for fecal microbiota transplantation should be classified as a transplant product and not as a drug', UNITED EUROPEAN GASTROENTEROLOGY JOURNAL, 7, pp. 1408 - 1410,
    Journal articles | 2019
    Mahalhal A; Burkitt M; Duckworth C; Hold G; Campbell B; Pritchard M; Probert C, 2019, 'Long-term iron deficiency and iron supplementation exacerbate acute DSS-induced colitis and are associated with significant dysbiosis', ,
    Journal articles | 2019
    Mukhopadhya I; Segal JP; Carding SR; Hart AL; Hold GL, 2019, 'The gut virome: the ‘missing link’ between gut bacteria and host immunity?', Therapeutic Advances in Gastroenterology, 12,
    Journal articles | 2019
    Ormsby MJ; Logan M; Johnson SA; McIntosh A; Fallata G; Papadopoulou R; Papachristou E; Hold GL; Hansen R; Ijaz UZ; Russell RK; Gerasimidis K; Wall DM, 2019, 'Inflammation associated ethanolamine facilitates infection by Crohn's disease-linked adherent-invasive Escherichia coli', EBioMedicine, 43, pp. 325 - 332,
    Journal articles | 2019
    Rokkas T; Gisbert JP; Gasbarrini A; Hold GL; Tilg H; Malfertheiner P; Megraud F; O'Morain C, 2019, 'A network meta-analysis of randomized controlled trials exploring the role of fecal microbiota transplantation in recurrent Clostridium difficile infection', United European Gastroenterology Journal, 7, pp. 1051 - 1063,
    Journal articles | 2018
    Brunner K; John CM; Phillips NJ; Alber DG; Gemmell MR; Hansen R; Nielsen HL; Hold GL; Bajaj-Elliott M; Jarvis GA, 2018, 'Novel Campylobacter concisus lipooligosaccharide is a determinant of inflammatory potential and virulence', Journal of Lipid Research, 59, pp. 1893 - 1905,
    Journal articles | 2018
    Douglas GM; Hansen R; Jones CMA; Dunn KA; Comeau AM; Bielawski JP; Tayler R; El-Omar EM; Russell RK; Hold GL; Langille MGI; Limbergen JV, 2018, 'Multi-omics differentially classify disease state and treatment outcome in pediatric Crohn's disease', Microbiome, 6, pp. 13,
    Journal articles | 2018
    Garg M; Hendy P; Ding JN; Shaw S; Hold G; Hart A, 2018, 'The effect of Vitamin D on intestinal inflammation and faecal microbiota in patients with ulcerative colitis', Journal of Crohn's and Colitis, 12, pp. 963 - 972,
    Journal articles | 2018
    Gemmell MR; Berry S; Mukhopadhya I; Hansen R; Nielsen HL; Bajaj-Elliott M; Nielsen H; Hold GL, 2018, 'Comparative genomics of Campylobacter concisus: Analysis of clinical strains reveals genome diversity and pathogenic potential', Emerging Microbes and Infections, 7,
    Journal articles | 2018
    Hansen R; Gibson S; De Paiva Alves E; Goddard M; MacLaren A; Karcher AM; Berry S; Collie-Duguid ESR; El-Omar E; Munro M; Hold GL, 2018, 'Adaptive response of neonatal sepsis-derived Group B Streptococcus to bilirubin', Scientific Reports, 8,
    Journal articles | 2018
    Ianiro G; Maida M; Burisch J; Simonelli C; Hold G; Ventimiglia M; Gasbarrini A; Cammarota G, 2018, 'Efficacy of different faecal microbiota transplantation protocols for Clostridium difficile infection: A systematic review and meta-analysis', United European Gastroenterology Journal, 6, pp. 1232 - 1244,
    Journal articles | 2018
    Kennedy NA; Lamb CA; Berry SH; Walker AW; Mansfield J; Parkes M; Simpkins R; Tremelling M; Nutland S; Parkhill J; Probert C; Hold GL; Lees CW, 2018, 'The impact of NOD2 variants on fecal microbiota in Crohn's disease and controls without gastrointestinal disease', Inflammatory Bowel Diseases, 24, pp. 583 - 592,
    Journal articles | 2018
    Kupcinskas J; Hold GL, 2018, 'Other Helicobacters and the gastric microbiome', Helicobacter, 23,
    Journal articles | 2018
    Mahalhal A; Williams J; Johnson S; Ellaby N; Duckworth C; Burkitt M; Liu X; Hold G; Campbell B; Pritchard M; Probert C, 2018, 'Oral iron exacerbates colitis and influences the intestinal microbiome', ,
    Journal articles | 2018
    Mahalhal A; Williams JM; Johnson S; Ellaby N; Duckworth CA; Burkitt MD; Liu X; Hold GL; Campbell BJ; Mark Pritchard D; Probert CS, 2018, 'Oral iron exacerbates colitis and influences the intestinal microbiome', PLoS ONE, 13,
    Journal articles | 2018
    McIlroy J; Ianiro G; Mukhopadhya I; Hansen R; Hold GL, 2018, 'Review article: the gut microbiome in inflammatory bowel disease—avenues for microbial management', Alimentary Pharmacology and Therapeutics, 47, pp. 26 - 42,
    Journal articles | 2018
    McIlroy J; Nalagatla N; Hansen R; Hart A; Hold G, 2018, 'P659 FMT as a treatment for IBD: A national survey of gastroenterologists in the UK', Journal of Crohn's and Colitis, 12, pp. S443 - S444,
    Journal articles | 2018
    McIlroy JR; Nalagatla N; Hansen R; Hart A; Hold GL, 2018, 'Faecal microbiota transplantation as a treatment for inflammatory bowel disease: A national survey of adult and paediatric gastroenterologists in the UK', Frontline Gastroenterology, 9, pp. 250 - 255,
    Journal articles | 2018
    Segal JP; Oke S; Hold GL; Clark SK; Faiz OD; Hart AL, 2018, 'Systematic review: ileoanal pouch microbiota in health and disease', Alimentary Pharmacology and Therapeutics, 47, pp. 466 - 477,
    Journal articles | 2017
    Berry SH; El-Omar EM; Hold GL; Mukhopadhya A, 2017, 'THE EFFECT OF LACTULOSE ON THE FAECAL MICROBIOTA OF PATIENTS WITH MINIMAL HEPATIC ENCEPHALOPATHY', GASTROENTEROLOGY, 152, pp. S1049 - S1049,
    Journal articles | 2017
    Boyle SE; Cotton SC; Myint PK; Hold GL, 2017, 'The influence of early research experience in medical school on the decision to intercalate and future career in clinical academia: A questionnaire study', BMC Medical Education, 17, pp. 245,
    Journal articles | 2017
    Maida M; Macaluso FS; Ianiro G; Mangiola F; Sinagra E; Hold G; Maida C; Cammarota G; Gasbarrini A; Scarpulla G, 2017, 'Screening of colorectal cancer: present and future', Expert Review of Anticancer Therapy, 17, pp. 1131 - 1146,
    Journal articles | 2017
    Mukhopadhya I; Murdoch H; Berry S; Hunt A; Iturriza-Gomara M; Smith-Palmer A; Cameron JC; Hold GL, 2017, 'Changing molecular epidemiology of rotavirus infection after introduction of monovalent rotavirus vaccination in Scotland', Vaccine, 35, pp. 156 - 163,
    Journal articles | 2016
    Hold GL, 2016, 'Gastrointestinal Microbiota and Colon Cancer', Digestive Diseases, 34, pp. 244 - 250,
    Journal articles | 2016
    Marchesi JR; Adams DH; Fava F; Hermes GDA; Hirschfield GM; Hold G; Quraishi MN; Kinross J; Smidt H; Tuohy KM; Thomas LV; Zoetendal EG; Hart A, 2016, 'The gut microbiota and host health: A new clinical frontier', Gut, 65, pp. 330 - 339,
    Journal articles | 2016
    Mukhopadhya I; Murray GI; Berry S; Thomson J; Frank B; Gwozdz G; Ekeruche-Makinde J; Shattock R; Kelly C; Iannelli F; Pozzi G; El-Omar EM; Hold GL; Hijazi K, 2016, 'Drug transporter gene expression in human colorectal tissue and cell lines: Modulation with antiretrovirals for microbicide optimization', Journal of Antimicrobial Chemotherapy, 71, pp. 372 - 386,
    Journal articles | 2016
    Mukhopadhya I; Murray GI; Duncan L; Yuecel R; Shattock R; Kelly C; Iannelli F; Pozzi G; El-Omar EM; Hold GL; Hijazi K, 2016, 'Transporters for antiretroviral drugs in colorectal CD4+ T cells and circulating α4β7 integrin CD4+ T cells: Implications for HIV microbicides', Molecular Pharmaceutics, 13, pp. 3334 - 3340,
    Journal articles | 2016
    Porter R; Murray R; Petty R; El-Omar EM; Hold GL; McLean MH, 2016, 'PTU-154 HMGB1 As a Prognostic Biomarker in The Progression of Barrett’s Oesophagus', Gut, 65, pp. A133.1 - A133,
    Journal articles | 2016
    Watt E; Gemmell MR; Berry S; Glaire M; Farquharson F; Louis P; Murray GI; El-Omar E; Hold GL, 2016, 'Extending colonic mucosal microbiome analysis-assessment of colonic lavage as a proxy for endoscopic colonic biopsies', Microbiome, 4, pp. 61,
    Journal articles | 2015
    Basavaraju U; Shebl FM; Palmer AJ; Berry S; Hold GL; El-Omar EM; Rabkin CS, 2015, 'Cytokine gene polymorphisms, cytokine levels and the risk of colorectal neoplasia in a screened population of Northeast Scotland', European Journal of Cancer Prevention, 24, pp. 296 - 304,
    Journal articles | 2015
    Connors J; Hansen R; Dunn KA; Langille MG; Russell RK; Otley AR; MacIntyre B; El-Omar E; Bielawski JP; Hold GL; Van Limbergen J, 2015, '169 Assessment of Community Structure and Predictive Functional Profiling of the Mucosa-Associated Microbiome Implicates Alterations in Benzoate Metabolism in ‘de novo’ IBD After Pouch-Surgery and in Treatment-Naïve Pediatric IBD', Gastroenterology, 148, pp. S - 45,
    Journal articles | 2015
    Hansen R; Scott KP; Khan S; Martin JC; Berry SH; Stevenson M; Okpapi A; Munro MJ; Hold GL, 2015, 'First-Pass Meconium Samples from Healthy Term Vaginally-Delivered Neonates: An Analysis of the Microbiota', PLoS ONE, 10,
    Journal articles | 2015
    Hijazi K; Cuppone AM; Smith K; Stincarelli MA; Ekeruche-Makinde J; De Falco G; Hold GL; Shattock R; Kelly CG; Pozzi G; Iannelli F, 2015, 'Expression of genes for drug transporters in the human female genital tract and modulatory effect of antiretroviral drugs', PLoS ONE, 10,
    Journal articles | 2015
    Hijazi K; Lowe T; Meharg C; Berry SH; Foley J; Hold GL, 2015, 'Mucosal microbiome in patients with recurrent aphthous stomatitis', Journal of Dental Research, 94, pp. 87S - 94S,
    Journal articles | 2015
    Hold GL; Garrett WS, 2015, 'Gut microbiota: Microbiota organization-a key to understanding CRC development', Nature Reviews Gastroenterology and Hepatology, 12, pp. 128 - 129,
    Journal articles | 2015
    Kennedy NA; Walker AW; Berry SH; Lamb CA; Lewis S; Mansfield JC; Parkes M; Parkhill J; Probert C; Read D; Satsangi J; Simpkins RL; Tomlinson D; Tremelling M; Nutland SL; Hold GL; Lees CW, 2015, 'Mo1816 The Impact of NOD2 Variants on Gut Microbiota in Crohn's Disease and Healthy Controls', Gastroenterology, 148, pp. S - 718,
    Journal articles | 2015
    Khan S; Hansen R; Scott KP; Martin JC; Berry SH; Stevenson M; Okapapi A; Hold GL; Munro M, 2015, 'G116(P) The human gut is probably sterile at birth', Archives of Disease in Childhood, 100, pp. A50.3 - A51,
    Journal articles | 2015
    Mukhopadhya I; Hansen R; Meharg C; Thomson JM; Russell RK; Berry SH; El-Omar EM; Hold GL, 2015, 'The fungal microbiota of de-novo paediatric inflammatory bowel disease', Microbes and Infection, 17, pp. 304 - 310,
    Journal articles | 2014
    Adams AT; Kennedy NA; Hansen R; Ventham NT; O'Leary KR; Drummond HE; Noble CL; El-Omar E; Russell RK; Wilson DC; Nimmo ER; Hold GL; Satsangi J, 2014, 'Two-stage genome-wide methylation profiling in childhood-onset Crohn's disease implicates epigenetic alterations at the VMP1/MIR21 and HLA loci', Inflammatory Bowel Diseases, 20, pp. 1784 - 1793,
    Journal articles | 2014
    Folmer F; Basavaraju U; Jaspars M; Hold G; El-Omar E; Dicato M; Diederich M, 2014, 'Anticancer effects of bioactive berry compounds', Phytochemistry Reviews, 13, pp. 295 - 322,
    Journal articles | 2014
    Hold GL; Berry S; Saunders KA; Drew J; Mayer C; Brookes H; Gay NJ; El-Omar EM; Bryant CE, 2014, 'The TLR4 D299G and T399I SNPs are constitutively active to up-regulate expression of Trif-dependent genes', PLoS ONE, 9, pp. e111460,
    Journal articles | 2014
    Hold GL; Mukhopadhya I; Hansen R, 2014, 'Diet, the microbiome, and IBD', Inflammatory Bowel Disease Monitor, 14, pp. 39 - 43
    Journal articles | 2014
    Hold GL; Smith M; Grange C; Watt ER; El-Omar EM; Mukhopadhya I, 2014, 'Role of the gut microbiota in inflammatory bowel disease pathogenesis: What have we learnt in the past 10 years?', World Journal of Gastroenterology, 20, pp. 1192 - 1210,
    Journal articles | 2014
    Hold GL, 2014, 'The gut microbiota, dietary extremes and exercise', Gut, 63, pp. 1838 - 1839,
    Journal articles | 2014
    Hold GL, 2014, 'Western lifestyle: A 'master' manipulator of the intestinal microbiota?', Gut, 63, pp. 5 - 6,
    Journal articles | 2014
    Kennedy NA; Adams AT; Hansen R; Ventham NT; O'Leary KR; Drummond H; Noble CL; El-Omar E; Russell RK; Wilson DC; Nimmo ER; Hold GL; Satsangi J, 2014, 'Epigenome-wide analysis in childhood-onset Crohn's disease implicates MIR21 in pathogenesis and identifies multiple methylation-based diagnostic biomarkers', JOURNAL OF CROHNS & COLITIS, 8, pp. S19 - S19,
    Journal articles | 2014
    Kennedy NA; Walker AW; Berry SH; Duncan SH; Farquarson FM; Louis P; Thomson JM; Satsangi J; Flint HJ; Parkhill J; Lees CW; Hold GL, 2014, 'The impact of different DNA extraction kits and laboratories upon the assessment of human gut microbiota composition by 16S rRNA gene sequencing', PLoS ONE, 9,
    Journal articles | 2014
    Lochhead PJ; Mayer C-D; Hold GL; El-Omar E, 2014, '946 Genome-Wide Analysis of DNA Methylation in Low-Grade Colorectal Adenomas and Normal Colonic Mucosa', Gastroenterology, 146, pp. S - 165,
    Journal articles | 2014
    Louis P; Hold GL; Flint HJ, 2014, 'The gut microbiota, bacterial metabolites and colorectal cancer', Nature Reviews Microbiology, 12, pp. 661 - 672,
    Journal articles | 2014
    Mactier KE; Glaire MA; Basavaraju U; El-Omar EM; Hold GL, 2014, 'MicroRNAs in gastrointestinal malignancy: A tool in cancer prevention?', European Journal of Cancer Prevention, 23, pp. 540 - 549,
    Journal articles | 2013
    Hansen R; Berry SH; Mukhopadhya I; Thomson JM; Saunders KA; Nicholl CE; Bisset WM; Loganathan S; Mahdi G; Kastner-Cole D; Barclay AR; Bishop J; Flynn DM; McGrogan P; Russell RK; El-Omar EM; Hold GL, 2013, 'The Microaerophilic Microbiota of De-Novo Paediatric Inflammatory Bowel Disease: The BISCUIT Study', PLoS ONE, 8, pp. e58825,
    Journal articles | 2013
    Hansen R; Mukhopadhya I; Meharg C; Russell RK; Berry SH; El-Omar E; Hold GL, 2013, 'Tu1704 The Role of the Fungal Microbiota in the Pathogenesis of De-Novo Pediatric Inflammatory Bowel Disease Using Next Generation Sequencing', Gastroenterology, 144, pp. S - 826,
    Journal articles | 2013
    Hold GL; Hope M; Lochhead P; Meharg C; Berry SH; El-Omar E, 2013, 'Sa1972 Assessment of Bacterial Diversity in Colorectal Adenomatous Polyps', Gastroenterology, 144, pp. S - 348,
    Journal articles | 2013
    Kennedy N; Walker A; Berry S; Duncan S; Farquharson F; Louis P; Satsangi J; Flint H; Lees C; Hold G, 2013, 'PTU-072 Evaluation of the Impact of different Commercially available DNA Extraction Kits and Laboratories for Assessing Bacterial Community Structure in Faecal Samples – Implications for IBD Research', Gut, 62, pp. A74.1 - A74,
    Journal articles | 2013
    Kennedy NA; Hildebrand D; Berry SH; Satsangi J; Hold GL, 2013, 'PWE-108 Assessment of the Mucosal Microbiota in Inflammatory Bowel Disease', Gut, 62, pp. A174.2 - A175,
    Journal articles | 2013
    Kennedy NA; Walker A; IBD Microbiota Consortia UK; IBD Genetics Consortia UK; Berry SH; Duncan SH; Farquharson F; Louis P; Satsangi J; Flint HJ; Lees CW; Hold GL, 2013, 'Tu1716 Evaluation of the Impact of Different Commercially Available DNA Extraction Kits and Laboratories for Assessing Bacterial Community Structure in Fecal Samples - Implications for IBD Research', Gastroenterology, 144, pp. S - 829,
    Journal articles | 2013
    Kennedy NA; Walker AW; Berry SH; Duncan SH; Farquarson F; Louis P; Satsangi J; Flint HJ; Lees CW; Hold GL, 2013, 'P705 Evaluation of the impact of different commercially available DNA extraction kits and laboratories for assessing bacterial community structure in fecal samples – implications for IBD research', Journal of Crohn's and Colitis, 7, pp. S294 - S294,
    Journal articles | 2013
    Kostic AD; Chun E; Robertson L; Glickman JN; Gallini CA; Michaud M; Clancy TE; Chung DC; Lochhead P; Hold GL; El-Omar EM; Brenner D; Fuchs CS; Meyerson M; Garrett WS, 2013, 'Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment', Cell Host and Microbe, 14, pp. 207 - 215,
    Journal articles | 2013
    McLean MH; Thomson AJ; Murray GI; Fyfe N; Hold GL; El-Omar EM, 2013, 'Expression of neutrophil gelatinase-associated lipocalin in colorectal neoplastic progression: A marker of malignant potential?', British Journal of Cancer, 108, pp. 2537 - 2541,
    Journal articles | 2013
    Watt E; Berry SH; Farquharson F; Glaire MA; Thomson JM; El-Omar E; Louis P; Hold GL, 2013, 'Tu1729 Evaluation of Fecal Aspirate As a Proxy for Colonoscopy Biopsy Sampling to Assess Microbial Diversity', Gastroenterology, 144, pp. S - 832,
    Journal articles | 2012
    Hansen R; Russell RK; Reiff C; Louis P; McIntosh F; Berry SH; MGBRhopadhya I; Bisset WM; Barclay AR; Bishop J; Flynn DM; McGrogan P; Loganathan S; Mahdi G; Flint HJ; El-Omar EM; Hold GL, 2012, 'Microbiota of de-novo pediatric IBD: Increased faecalibacterium prausnitzii and reduced bacterial diversity in Crohn's but not in ulcerative colitis', American Journal of Gastroenterology, 107, pp. 1913 - 1922,
    Journal articles | 2012
    Hird HJ; Chisholm J; Kaye J; Colyer A; Hold G; Conyers CM; Núñez JI; Macarthur R, 2012, 'Development of real-time PCR assays for the detection of Atlantic cod (Gadus morhua), Atlantic salmon (Salmo salar) and European plaice (Pleuronectes platessa) in complex food samples', European Food Research and Technology, 234, pp. 127 - 136,
    Journal articles | 2012
    Mukhopadhya I; Hansen R; El-Omar EM; Hold GL, 2012, 'IBD-what role do Proteobacteria play?', Nature Reviews Gastroenterology and Hepatology, 9, pp. 219 - 230,
    Journal articles | 2012
    Palmer AJ; Lochhead P; Hold GL; Rabkin CS; Chow WH; Lissowska J; Vaughan TL; Berry S; Gammon M; Risch H; El-Omar EM, 2012, 'Genetic variation in C20orf54, PLCE1 and MUC1 and the risk of upper gastrointestinal cancers in Caucasian populations', European Journal of Cancer Prevention, 21, pp. 541 - 544,
    Journal articles | 2012
    Palmer AJ; Lochhead P; Hold GL; Rabkin CS; Vaughan TL; Lissowska J; Chow W-H; Berry SH; El-Omar E, 2012, 'Mo1584 Genetic Variation in C20orf54, PLCE1 and MUC1 and Risk of Upper Gastrointestinal Cancers in Caucasian Populations', Gastroenterology, 142, pp. S - 634,
    Journal articles | 2012
    Raju D; Hussey S; Ang M; Terebiznik MR; Sibony M; Galindo-Mata E; Gupta V; Blanke SR; Delgado A; Romero-Gallo J; Ramjeet MS; Mascarenhas H; Peek RM; Correa P; Streutker C; Hold G; Kunstmann E; Yoshimori T; Silverberg MS; Girardin SE; Philpott DJ; El Omar E; Jones NL, 2012, 'Vacuolating cytotoxin and variants in Atg16L1 that disrupt autophagy promote helicobacter pylori infection in humans', Gastroenterology, 142, pp. 1160 - 1171,
    Journal articles | 2012
    Smith C; Lochhead P; Basavaraju U; Hold G; Fyfe N; Murray G; El-Omar E, 2012, 'LACK OF ASSOCIATION BETWEEN THE PSCA RS2294008 POLYMORPHISM, OR PSCA EXPRESSION, AND COLORECTAL NEOPLASIA', GUT, 61, pp. A327 - A328,
    Journal articles | 2012
    Smith C; Lochhead P; Basavaraju U; Hold GL; Fyfe N; Murray GI; El-Omar EM, 2012, 'Lack of association between the rs2294008 polymorphism in the prostate stem cell antigen gene and colorectal neoplasia: A case-control and immunohistochemical study', BMC Research Notes, 5, pp. 371,
    Journal articles | 2011
    Goddard M; Hansen R; Karcher AM; Munro MJ; Berry SH; Stevenson MH; El-Omar E; Hold GL, 2011, 'Bilirubin Has Anti-Bacterial Properties Against Gram-Positive Bacteria: A Potential Benefit of Physiological Jaundice?', Gastroenterology, 140, pp. S - 941,
    Journal articles | 2011
    Haag AF; Wehmeier S; Muszyński A; Kerscher B; Fletcher V; Berry SH; Hold GL; Carlson RW; Ferguson GP, 2011, 'Biochemical characterization of Sinorhizobium meliloti mutants reveals gene products involved in the biosynthesis of the unusual lipid A very long-chain fatty acid', Journal of Biological Chemistry, 286, pp. 17455 - 17466,
    Journal articles | 2011
    Hansen R; El-Omar E; Hold GL, 2011, 'Characterizing the microbiota in IBD', Inflammatory Bowel Disease Monitor, 12, pp. 1 - 7
    Journal articles | 2011
    Hansen R; Mukhopadhya I; Russell RK; Bisset WM; Berry SH; Thomson JM; El-Omar E; Hold GL, 2011, 'The Role of the Microaerophilic Colonic Microbiota in De-Novo Paediatric Inflammatory Bowel Disease', Gastroenterology, 140, pp. S - 512,
    Journal articles | 2011
    Hansen R; Reiff C; Russell RK; Bisset WM; Berry SH; Mukhopadhya I; Thomson JM; El-Omar E; Hold GL, 2011, 'Bacterial Diversity of the Colonic Microbiota in De-Novo Extensive Paediatric Ulcerative Colitis by Next-Generation Sequencing', Gastroenterology, 140, pp. S - 196,
    Journal articles | 2011
    Hansen R; Thomson JM; Fox JG; El-Omar EM; Hold GL, 2011, 'Could Helicobacter organisms cause inflammatory bowel disease?', FEMS Immunology and Medical Microbiology, 61, pp. 1 - 14,
    Journal articles | 2011
    Lochhead P; Frank B; Hold GL; Rabkin CS; Ng MTH; Vaughan TL; Risch HA; Gammon MD; Lissowska J; Weck MN; Raum E; Mller H; Illig T; Klopp N; Dawson A; McColl KE; Brenner H; Chow W; Elomar EM, 2011, 'Genetic variation in the prostate stem cell antigen gene and upper gastrointestinal cancer in white individuals', Gastroenterology, 140, pp. 435 - 441,
    Journal articles | 2011
    Lochhead P; Ng MTH; Hold GL; Rabkin CS; Vaughan TL; Gammon MD; Risch HA; Lissowska J; Mukhopadhya I; Chow WH; El-Omar EM, 2011, 'Possible association between a genetic polymorphism at 8q24 and risk of upper gastrointestinal cancer', European Journal of Cancer Prevention, 20, pp. 54 - 57,
    Journal articles | 2011
    McLean MH; Murray GI; Stewart KN; Norrie G; Mayer C; Hold GL; Thomson J; Fyfe N; Hope M; Mowat NAG; Drew JE; El-Omar EM, 2011, 'The inflammatory microenvironment in colorectal Neoplasia', PLoS ONE, 6, pp. e15366,
    Journal articles | 2011
    Monie TP; Hold GL; Mukhopadhya I, 2011, 'Innate immune sensors and gastrointestinal bacterial infections', Clinical and Developmental Immunology, 2011,
    Journal articles | 2011
    Mukhopadhya I; Hansen R; Nicholl CE; Alhaidan YA; Thomson JM; Berry SH; Pattinson C; Stead DA; Russell RK; El-Omar EM; Hold GL, 2011, 'A comprehensive evaluation of colonic mucosal isolates of sutterella wadsworthensis from inflammatory bowel disease', PLoS ONE, 6, pp. e27076,
    Journal articles | 2011
    Mukhopadhya I; Thomson JM; Hansen R; Berry SH; El-Omar E; Hold GL, 2011, 'Detection of Campylobacter Concisus in Colonic Biopsies From Adult Patients With Ulcerative Colitis', Gastroenterology, 140, pp. S - 268,
    Journal articles | 2011
    Mukhopadhya I; Thomson JM; Hansen R; Berry SH; El-Omar EM; Hold GL, 2011, 'Detection of Campylobacter concisus and other campylobacter species in colonic biopsies from adults with ulcerative colitis', PLoS ONE, 6, pp. e21490,
    Journal articles | 2011
    Smet A; Flahou B; Mukhopadhya I; Ducatelle R; Pasmans F; Haesebrouck F; Hold GL, 2011, 'The Other Helicobacters', Helicobacter, 16, pp. 70 - 75,
    Journal articles | 2011
    Thomson JM; Hansen R; Berry SH; Hope ME; Murray GI; Mukhopadhya I; McLean MH; Shen Z; Fox JG; El-Omar E; Hold GL, 2011, 'Enterohepatic Helicobacter in ulcerative colitis: Potential pathogenic entities?', PLoS ONE, 6, pp. e17184,
    Journal articles | 2010
    Basavaraju U; Shebl FM; Palmer AJ; Hold GL; Rabkin CS; El-Omar E, 2010, 'T2012 Cytokine Gene Polymorphisms, Cytokine Levels and Risk of Colorectal Neoplasia in the Screened Population of Northeast Scotland', Gastroenterology, 138, pp. S - 613,
    Journal articles | 2010
    El-Sakka NE; Hold GL; El-Omar E, 2010, 'W1738 Role of TLR4 in Carcinogenesis and Tumor Progression of Colorectal Cancer', Gastroenterology, 138, pp. S - 730,
    Journal articles | 2010
    FitzGerald MP; Wehmeier S; Gangloff M; Gay N; Berry SH; Ferguson GP; El-Omar E; Hold GL, 2010, 'S1640 Can Helicobacter pylori Lipopolysaccharide Lipid a Composition Affect Its Ability to Induce an Inflammatory Response Through Toll Like Receptor 4', Gastroenterology, 138, pp. S - 244,
    Journal articles | 2010
    Hansen R; Cameron FL; Hold GL; El-Omar EM; Russell RK, 2010, 'Inflammatory bowel disease', Paediatrics and Child Health, 20, pp. 473 - 478,
    Journal articles | 2010
    Hansen R; Thomson JM; El-Omar EM; Hold GL, 2010, 'The role of infection in the aetiology of inflammatory bowel disease', Journal of Gastroenterology, 45, pp. 266 - 276,
    Journal articles | 2010
    Ng MT; Rabkin CS; Lochhead P; Lissowska J; Vaughan TL; Gammon M; Risch H; Chow W-H; Hold GL; El-Omar E, 2010, 'T2009 Assessment of Novel Genetic Polymorphisms and Risk of Upper Gastrointestinal Carcinoma', Gastroenterology, 138, pp. S - 612,
    Journal articles | 2010
    Ng MTH; Van't Hof R; Crockett JC; Hope ME; Berry S; Thomson J; McLean MH; McColl KEL; El-Omar EM; Hold GL, 2010, 'Increase in NF-κB binding affinity of the variant C allele of the toll-like receptor 9 -1237T/C polymorphism is associated with Helicobacter pylori-induced gastric disease', Infection and Immunity, 78, pp. 1345 - 1352,
    Journal articles | 2010
    Saunders KA; Crockett JC; Berry SH; El-Omar E; Hold GL, 2010, 'S1641 Impact of the TLR4 Asp299Gly Polymorphism on Induction of the Inflammatory Response Following H. pylori Infection', Gastroenterology, 138, pp. S - 244,
    Journal articles | 2009
    Hansen R; El-Sakka NE; Berry SH; Thomson JM; Bisset WM; Mahdi G; Murray GI; Helms PJ; Hold G; El-Omar EM, 2009, 'W1180 Are Non-Pylori Helicobacter Organisms Associated with Paediatric Ulcerative Colitis? Retrospective Observational Study', Gastroenterology, 136, pp. A - 671,
    Journal articles | 2009
    Hansen R; Hold GL; Berry SH; El Sakka NE; Thomson J; Bisset WM; Mahdi G; Murray GI; Helms PJ; El-Omar E, 2009, 'Are non-Pylori Helicobacter Organisms Associated with Paediatric Ulcerative Colitis? A Retrospective Observational Study', SCOTTISH MEDICAL JOURNAL, 54, pp. 54 - 55,
    Journal articles | 2009
    Hold GL; Rabkin CS; Gammon MD; Berry SH; Smith MG; Lissowska J; Risch HA; Chow WH; Ashley G Mowat N; Vaughan TL; El-Omar EM, 2009, 'CD14-159C/T and TLR9-1237T/C polymorphisms are not associated with gastric cancer risk in Caucasian populations', European Journal of Cancer Prevention, 18, pp. 117 - 119,
    Journal articles | 2009
    Hold GL; Untiveros P; Saunders KA; El-Omar EM, 2009, 'Role of host genetics in fibrosis', Fibrogenesis and Tissue Repair, 2, pp. 6,
    Journal articles | 2008
    El-Omar EM; Ng MT; Hold GL, 2008, 'Polymorphisms in Toll-like receptor genes and risk of cancer', Oncogene, 27, pp. 244 - 252,
    Journal articles | 2008
    Hold GL; El-Omar EM, 2008, 'Genetic aspects of inflammation and cancer', Biochemical Journal, 410, pp. 225 - 235,
    Journal articles | 2008
    McLean MH; Drew JE; Mayer CD; Farquharson A; Barrera LN; Fyfe N; Murray GI; Hold G; Mowat NA; El-Omar E, 2008, 'Role of chronic inflammation in sporadic colorectal neoplasia', GASTROENTEROLOGY, 134, pp. A293 - A294,
    Journal articles | 2008
    McLean MH; Drew JE; Mayer CD; Farquharson A; Barrera LN; Fyfe N; Murray GI; Hold G; Mowat NA; El-Omar E, 2008, 'S1996 Role of Chronic Inflammation in Sporadic Colorectal Neoplasia', Gastroenterology, 134,
    Journal articles | 2008
    McLean MH; Murray GI; Fyfe N; Hold GL; Mowat NAG; El-Omar EM, 2008, 'COX-2 expression in sporadic colorectal adenomatous polyps is linked to adenoma characteristics', Histopathology, 52, pp. 806 - 815,
    Journal articles | 2008
    Ng MT; Crockett JC; Van't Hof R; Berry SH; El-Omar E; Hold G, 2008, 'A single nucleotide polymorphism in the TLR9 promoter (TLR9-1237T/C) increases the affinity of NF-kappa B protein binding and enhances transcriptional activity upon H-pylori infection', GASTROENTEROLOGY, 134, pp. A567 - A567,
    Journal articles | 2008
    Ng MT; Crockett JC; Van't Hof R; Berry SH; El-Omar E; Hold G, 2008, 'T1807 A Single Nucleotide Polymorphism in the TLR9 Promoter (TLR9 −1237T/C) Increases the Affinity of NF-κB Protein Binding and Enhances Transcriptional Activity Upon H. pylori Infection', Gastroenterology, 134, pp. A - 567,
    Journal articles | 2008
    Thomson JM; Hold G; Berry SH; El-Sakka NE; Mowat NA; Shen Z; Taylor NS; Fox JG; El-Omar E, 2008, 'Variable detection of entero-hepatic Helicobacter species in colonic mucosal pinch biopsies by different molecular techniques', GASTROENTEROLOGY, 134, pp. A655 - A655,
    Journal articles | 2008
    Thomson JM; Hold G; Berry SH; El-Sakka NE; Mowat NA; Shen Z; Taylor NS; Fox JG; El-Omar E, 2008, 'W1208 Variable Detection of Entero-Hepatic Helicobacter Species in Colonic Mucosal Pinch Biopsies By Different Molecular Techniques', Gastroenterology, 134, pp. A - 655,
    Journal articles | 2007
    Hold GL; Rabkin CS; Chow WH; Smith MG; Gammon MD; Risch HA; Vaughan TL; McColl KEL; Lissowska J; Zatonski W; Schoenberg JB; Blot WJ; Mowat NAG; Fraumeni JF; El-Omar EM, 2007, 'A Functional Polymorphism of Toll-Like Receptor 4 Gene Increases Risk of Gastric Carcinoma and Its Precursors', Gastroenterology, 132, pp. 905 - 912,
    Journal articles | 2006
    Smith MG; Hold GL; Tahara E; El-Omar EM, 2006, 'Cellular and molecular aspects of gastric cancer', World Journal of Gastroenterology, 12, pp. 2979 - 2990,
    Journal articles | 2005
    Garza-González E; Bosques-Padilla FJ; El-Omar E; Hold G; Tijerina-Menchaca R; Maldonado-Garza HJ; Pérez-Pérez GI, 2005, 'Role of the polymorphic IL-1B, IL-1RN and TNF-A genes in distal gastric cancer in Mexico', International Journal of Cancer, 114, pp. 237 - 241,
    Journal articles | 2005
    Hird HJ; Hold GL; Chisholm J; Reece P; Russell VJ; Brown J; Goodier R; MacArthur R, 2005, 'Development of a method for the quantification of haddock (Melanogrammus aeglefinus) in commercial products using real-time PCR', European Food Research and Technology, 220, pp. 633 - 637,
    Journal articles | 2005
    Hope ME; Hold GL; Kain R; El-Omar EM, 2005, 'Sporadic colorectal cancer - Role of the commensal microbiota', FEMS Microbiology Letters, 244, pp. 1 - 7,
    Journal articles | 2005
    Macarthur M; Sharp L; Hold GL; Little J; El-Omar EM, 2005, 'The role of cytokine gene polymorphisms in colorectal cancer and their interaction with aspirin use in the Northeast of Scotland', Cancer Epidemiology Biomarkers and Prevention, 14, pp. 1613 - 1618,
    Journal articles | 2004
    Macarthur M; Hold GL; El-Omar EM, 2004, 'Inflammation and Cancer II. Role of chronic inflammation and cytokine gene polymorphisms in the pathogenesis of gastrointestinal malignancy', American Journal of Physiology - Gastrointestinal and Liver Physiology, 286,
    Journal articles | 2004
    Maxwell FJ; Duncan SH; Hold G; Stewart CS, 2004, 'Isolation, growth on prebiotics and probiotic potential of novel bifidobacteria from pigs', Anaerobe, 10, pp. 33 - 39,
    Journal articles | 2003
    Calo-Mata P; Sotelo CG; Pérez-Martín RI; Rehbein H; Hold GL; Russell VJ; Pryde S; Quinteiro J; Rey-Méndez M; Rosa C; Santos AT, 2003, 'Identification of gadoid fish species using DNA-based techniques', European Food Research and Technology, 217, pp. 259 - 264,
    Journal articles | 2003
    Garza-González E; Hold G; Pérez-Pérez GI; Bosques-Padilla FJ; Tijerina-Menchaca R; Maldonado-Garza HJ; el-Omar E, 2003, 'Role of polymorphism of certain cytokines in gastric cancer in Mexico. Preliminary results', Revista de gastroenterología de México, 68, pp. 107 - 112
    Journal articles | 2003
    Hold GL; Schwiertz A; Aminov RI; Blaut M; Flint HJ, 2003, 'Oligonucleotide probes that detect quantitatively significant groups of butyrate-producing bacteria in human feces', Applied and Environmental Microbiology, 69, pp. 4320 - 4324,
    Journal articles | 2003
    Strömpl C; Hold GL; Lünsdorf H; Graham J; Gallacher S; Abraham WR; Moore ERB; Timmis KN, 2003, 'Oceanicaulis alexandrii gen. nov., sp. nov., a novel stalked bacterium isolated from a culture of the dinoflagellate Alexandrium tamarense (Lebour) Balech', International Journal of Systematic and Evolutionary Microbiology, 53, pp. 1901 - 1906,
    Journal articles | 2003
    Troost E; Hold GL; Smith MG; Chow WH; Rabkin CS; McColl KEL; El-Omar EM, 2003, 'The role of interleukin-1beta and other potential genetic markers as indicators of gastric cancer risk.', Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 17 Suppl B,
    Journal articles | 2002
    Chapela MJ; Sotelo CG; Calo-Mata P; Pérez-Martín RI; Rehbein H; Hold GL; Quinteiro J; Rey-Méndez M; Rosa C; Santos AT, 2002, 'Identification of Cephalopod Species (Ommastrephidae and Loliginidae) in Seafood Products by Forensically Informative Nucleotide Sequencing (FINS)', Journal of Food Science, 67, pp. 1672 - 1676,
    Journal articles | 2002
    Duncan SH; Hold GL; Barcenilla A; Stewart CS; Flint HJ, 2002, 'Roseburia intestinalis sp. nov., a novel saccharolytic, butyrate-producing bacterium from human faeces', International Journal of Systematic and Evolutionary Microbiology, 52, pp. 1615 - 1620,
    Journal articles | 2002
    Duncan SH; Hold GL; Harmsen HJM; Stewart CS; Flint HJ, 2002, 'Growth requirements and fermentation products of Fusobacterium prausnitzii, and a proposal to reclassify it as Faecalibacterium prausnitzii gen. nov., comb. nov', International Journal of Systematic and Evolutionary Microbiology, 52, pp. 2141 - 2146,
    Journal articles | 2002
    Duncan SH, 2002, 'Growth requirements and fermentation products of Fusobacterium prausnitzii, and a proposal to reclassify it as Faecalibacterium prausnitzii gen. nov., comb. nov', INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, 52, pp. 2141 - 2146,
    Journal articles | 2002
    Hold G, 2002, 'Assessment of microbial diversity in human colonic samples by 16S rDNA sequence analysis', FEMS Microbiology Ecology, 39, pp. 33 - 39,
    Journal articles | 2002
    Hold GL; Pryde SE; Russell VJ; Furrie E; Flint HJ, 2002, 'Assessment of microbial diversity in human colonic samples by 16S rDNA sequence analysis', FEMS Microbiology Ecology, 39, pp. 33 - 39,
    Journal articles | 2002
    Pryde S, 2002, 'The microbiology of butyrate formation in the human colon', FEMS Microbiology Letters, 217, pp. 133 - 139,
    Journal articles | 2002
    Pryde SE; Duncan SH; Hold GL; Stewart CS; Flint HJ, 2002, 'The microbiology of butyrate formation in the human colon', FEMS Microbiology Letters, 217, pp. 133 - 139,
    Journal articles | 2002
    Rehbein H; Sotelo CG; Perez-Martin RI; Chapela-Garrido MJ; Hold GL; Russell VJ; Pryde SE; Santos AT; Rosa C; Quinteiro J; Rey-Mendez M, 2002, 'Differentiation of raw or processed eel by PCR-based techniques: Restriction fragment length polymorphism analysis (RFLP) and single strand conformation polymorphism analysis (SSCP)', European Food Research and Technology, 214, pp. 171 - 177,
    Journal articles | 2002
    Rehbein H; Sotelo CG; Perez-Martin RI; Chapela-Garrido MJ; Hold GL; Russell VJ; Pryde SE; Santos AT; Rosa C; Quinteiro J; Rey-Mendez M, 2002, 'Differentiation of raw or processed eel by PCR-based techniques: restriction fragment length polymorphism analysis (RFLP) and single strand conformation polymorphism analysis (SSCP)', EUROPEAN FOOD RESEARCH AND TECHNOLOGY, 214, pp. 171 - 177,
    Journal articles | 2002
    Schwiertz A; Hold GL; Duncan SH; Gruhl B; Collins MD; Lawson PA; Flint HJ; Blaut M, 2002, 'Anaerostipes caccae gen. nov., sp. nov., a new saccharolytic, acetate-utilising, butyrate-producing bacterium from human faeces', Systematic and Applied Microbiology, 25, pp. 46 - 51,
    Journal articles | 2001
    Hold G, 2001, 'Characterisation of bacterial communities associated with toxic and non-toxic dinoflagellates: Alexandrium spp. and Scrippsiella trochoidea', FEMS Microbiology Ecology, 37, pp. 161 - 173,
    Journal articles | 2001
    Hold G, 2001, 'Comparison of paralytic shellfish toxin (PST) production by the dinoflagellates Alexandrium lusitanicum NEPCC 253 and Alexandrium tamarense NEPCC 407 in the presence and absence of bacteria', FEMS Microbiology Ecology, 36, pp. 223 - 234,
    Journal articles | 2001
    Hold GL; Russell VJ; Pryde SE; Rehbein H; Quinteiro J; Rey-Mendez M; Sotelo CG; Pérez-Martin RI; Santos AT; Rosa C, 2001, 'Validation of a PCR-RFLP based method for the identification of salmon species in food products', European Food Research and Technology, 212, pp. 385 - 389,
    Journal articles | 2001
    Hold GL; Russell VJ; Pryde SE; Rehbein H; Quinteiro J; Vidal R; Rey-Mendez M; Sotelo CG; Perez-Martin RI; Santos AT; Rosa C, 2001, 'Development of a DNA-based method aimed at identifying the fish species present in food products', Journal of Agricultural and Food Chemistry, 49, pp. 1175 - 1179,
    Journal articles | 2001
    Hold GL; Smith EA; Harry Birkbeck T; Gallacher S, 2001, 'Comparison of paralytic shellfish toxin (PST) production by the dinoflagellates Alexandrium lusitanicum NEPCC 253 and Alexandrium tamarense NEPCC 407 in the presence and absence of bacteria', FEMS Microbiology Ecology, 36, pp. 223 - 234,
    Journal articles | 2001
    Hold GL; Smith EA; Rappé MS; Maas EW; Moore ERB; Stroempl C; Stephen JR; Prosser JI; Birkbeck TH; Gallacher S, 2001, 'Characterisation of bacterial communities associated with toxic and non-toxic dinoflagellates: Alexandrium spp. and Scrippsiella trochoidea', FEMS Microbiology Ecology, 37, pp. 161 - 173,
    Journal articles | 2001
    Quinteiro J; Vidal R; Izquierdo M; Sotelo CG; Chapela MJ; Pérez-Martín RI; Rehbein H; Hold GL; Russell VJ; Pryde SE; Rosa C; Santos AT; Rey-Méndez M, 2001, 'Identification of hake species (Merluccius genus) using sequencing and PCR-RFLP analysis of mitochondrial DNA control region sequences', Journal of Agricultural and Food Chemistry, 49, pp. 5108 - 5114,
    Journal articles | 2001
    Sotelo CG; Calo-Mata P; Chapela MJ; Pérez-Martín RI; Rehbein H; Hold GL; Russell VJ; Pryde S; Quinteiro J; Izquierdo M; Rey-Méndez M; Rosa C; Santos AT, 2001, 'Identification of flatfish (Pleuronectiforme) species using DNA-based techniques', Journal of Agricultural and Food Chemistry, 49, pp. 4562 - 4569,
    Journal articles | 2000
    Russell VJ; Hold GL; Pryde SE; Rehbein H; Quinteiro J; Rey-Mendez M; Sotelo CG; Pérez-Martin RI; Santos AT; Rosa C, 2000, 'Use of restriction fragment length polymorphism to distinguish between salmon species', Journal of Agricultural and Food Chemistry, 48, pp. 2184 - 2188,
  • Conference Papers | 2024
    Rimmer P; Scott G; Quraishi MN; Hazel K; Cooney R; Hold G; Zhang F; Gordon M; Iqbal T; Hansen R, 2024, 'P107 Is gut microbiome diversity important at IBD onset? A systematic review of the literature and meta-analysis of alpha diversity data', in Poster Presentations, BMJ Publishing Group Ltd and British Society of Gastroenterology, pp. A114 - A115, presented at BSG LIVE’24, 17-20 June 2024, ICC Birmingham,
    Preprints | 2024
    Tearle JLE; Zhang F; Jackson KJL; Malhotra P; Tavakoli P; Koentgen S; Warren J; Williams C; Haque A; Arzivian A; Tedla N; Kim A; King HW; Hold GL; Ghaly S; James KR, 2024, The primary sclerosing cholangitis and ulcerative colitis colonic mucosa defined through paired microbial and single-cell RNA sequencing,
    Conference Abstracts | 2022
    Tavakoli P; Wu N; Shapiro AJ; Sanchez-Lomba B; Pipicella JL; Lo L; Williams A-J; Ghaly S; Leach ST; Corte C; Burke C; Samocha-Bonet D; Lambert K; Wasinger V; Dutt S; Pavli P; Grimm MC; Lemberg D; Connor S; Leong R; Hold G; Paramsothy R; O'Brien C, 2022, 'A snapshot of inflammatory bowel disease in Australia: Interim analysis of the Australian IBD Microbiome (AIM) Study cohort', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY, Vol. 37, pp. 159 - 159,
    Conference Abstracts | 2021
    Bridge S; Nelson A; Kennedy N; Lodge J; Morgan H; Berry S; Simpkins R; Tremelling M; Nutland S; Probert C; Parkes M; Mansfield J; Smith D; Hold G; Lees C; Stewart C; Lamb C, 2021, 'THE IMPACT OF NOD2 DEFICIENCY ON THE GUT MYCOBIOTA IN CROHN'S DISEASE PATIENTS IN REMISSION', in GUT, BMJ PUBLISHING GROUP, Vol. 70, pp. A86 - A86,
    Conference Papers | 2018
    McIlroy J; Nalagatla N; Hansen R; Hart A; Hold G, 2018, 'FMT as a treatment for IBD: A national survey of gastroenterologists in the UK', in JOURNAL OF CROHNS & COLITIS, OXFORD UNIV PRESS, pp. S443 - S444,
    Conference Papers | 2018
    Mcilroy J; Nalagatla N; Hansen R; Hart A; Hold G, 2018, 'FMT AS A TREATMENT FOR IBD: A NATIONAL SURVEY OF GASTROENTEROLOGISTS IN THE UK', in GUT, BMJ PUBLISHING GROUP, ENGLAND, Liverpool, pp. A86 - A86, presented at Annual General Meeting of the British-Society-of-Gastroenterology, ENGLAND, Liverpool, 04 June 2018 - 07 June 2018,
    Preprints | 2018
    Ormsby MJ; Johnson SA; Meikle LM; Goldstone RJ; McIntosh A; Wessel HM; Hulme HE; McConnachie CC; Connolly JPR; Roe AJ; Hasson C; Boyd J; Fitzgerald E; Gerasimidis K; Morrison D; Hold G; Hansen R; Smith DGE; Wall DM, 2018, Propionic acid promotes the virulent phenotype of Crohn’s disease-associated adherent-invasive Escherichia coli,
    Conference Papers | 2017
    Garg M; Hendy P; Shaw S; Ding JN; Hold G; Hart A, 2017, 'Vitamin D supplementation reduces fecal calprotectin and may alter microbiota composition in patients with active ulcerative colitis', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY, pp. 117 - 117,
    Conference Papers | 2017
    Gemmell M; Hsu T; Berry SH; Mukhopadhya I; Hansen R; Michaud M; El-Omar EM; Nielsen HL; Nielsen H; Huttenhower C; Garrett W; Hold GL, 2017, 'ELUCIDATING THE PATHOGENIC POTENTIAL OF THE INTESTINAL PATHOGEN CAMPYLOBACTER SHOWAE', in GUT, BMJ PUBLISHING GROUP, ENGLAND, Manchester, pp. A138 - A138, presented at Annual General Meeting of the British-Society-of-Gastroenterology (BSG), ENGLAND, Manchester, 19 June 2017 - 22 June 2017,
    Conference Papers | 2017
    Gemmell MR; Berry SH; Mukhopadhya I; Nielsen HL; Nielsen H; Hold GL, 2017, 'DEFINING GENOME DIVERSITY OF CAMPYLOBACTER CONCISUS BETWEEN ORAL, FAECAL AND COLONIC BIOPSY ISOLATES', in GUT, BMJ PUBLISHING GROUP, ENGLAND, Manchester, pp. A129 - A129, presented at Annual General Meeting of the British-Society-of-Gastroenterology (BSG), ENGLAND, Manchester, 19 June 2017 - 22 June 2017,
    Conference Papers | 2016
    Ferrand J; Hold GL; Ferrero RL; El-Omar EM; Gantier M, 2016, 'Toll-like receptor 8 polymorphisms in Helicobacter pylori infection', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, AUSTRALIA, Melbourne, pp. 637 - 637, presented at International Congress of Immunology (ICI), AUSTRALIA, Melbourne, 21 August 2016 - 26 August 2016,
    Conference Papers | 2016
    Hay A; Christopoulou CA; Murray GI; El-Omar EM; Hold GL; McLean MH, 2016, 'CYTOPLASMIC EXPRESSION OF HMGB1 IS ASSOCIATED WITH EARLY COLORECTAL CARCINOGENESIS', in GUT, BMJ PUBLISHING GROUP, pp. A192 - A192,
    Conference Papers | 2016
    Lalwani S; Mukhopadhya A; Fraser A; Hold GL; Bailey L; Vijayan B; English S; Mcleman L, 2016, 'NATURAL HISTORY OF CIRRHOSIS IN A COHORT OF PATIENTS UNDERGOING STRUCTURED SURVEILLANCE FOR HEPATOCELLULAR CARCINOMA: RESULTS FROM THE ABERDEEN SURVEILLANCE COHORT', in GUT, BMJ PUBLISHING GROUP, pp. A158 - A159,
    Conference Papers | 2016
    Mukhopadhya I; Hsu T; Nielsen H; Nielsen H; Berry S; Huttenhower C; Hold GL, 2016, 'ELUCIDATING THE ROLE OF NON JEJUNI/COLI-CAMPYLOBACTER IN THE DEVELOPMENT OF COLORECTAL CANCER UTILISING COMPARATIVE GENOMICS TO STUDY THEIR PATHOGENIC POTENTIAL', in GUT, BMJ PUBLISHING GROUP, pp. A188 - A189,
    Conference Papers | 2016
    Mukhopadhya I; Murray G; Duncan L; Yuecel R; Shattock R; Kelly C; Iannelli F; Pozzi G; El-Omar E; Hold G; Hijazi K, 2016, 'Transporters for Antiretroviral Drugs in Colorectal CD4+T Cells and Circulating alpha 4 beta 7 Integrin CD4+T Cells: Implications for HIV Microbicides', in AIDS RESEARCH AND HUMAN RETROVIRUSES, MARY ANN LIEBERT, INC, IL, Chicago, pp. 353 - 353, presented at Conference on HIV Research for Prevention (HIV R4P), IL, Chicago, 17 October 2016 - 20 October 2016,
    Conference Abstracts | 2015
    Connors J; Hansen R; Dunn KA; Langille MG; Russell RK; Otley AR; MacIntyre B; El-Omar E; Bielawski JP; Hold GL; Van Limbergen J, 2015, 'Assessment of Community Structure and Predictive Functional Profiling of the Mucosa-Associated Microbiome Implicates Alterations in Benzoate Metabolism in 'de novo' IBD After Pouch-Surgery and in Treatment-Naive Pediatric IBD', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, DC, Washington, Vol. 148, pp. S45 - S45, presented at 46th Annual Digestive Disease Week (DDW), DC, Washington, 16 May 2015 - 19 May 2015,
    Conference Abstracts | 2015
    Connors J; Hansen R; Dunn KA; Langille MG; Russell RK; Otley AR; MacIntyre B; El-Omar E; Bielawski JP; Hold GL; Van Limbergen J, 2015, 'Assessment of community structure and predictive functional profiling of the mucosa-associated microbiome implicates alterations in benzoate metabolism in 'de novo' IBD after pouch-surgery and in treatment-naive pediatric IBD', in JOURNAL OF CROHNS & COLITIS, OXFORD UNIV PRESS, Vol. 9, pp. S439 - S439,
    Conference Papers | 2015
    Kennedy NA; Walker AW; Berry SH; Lamb CA; Lewis S; Mansfield JC; Parkes M; Parkhill J; Probert C; Read D; Satsangi J; Simpkins RL; Tomlinson D; Tremelling M; Nutland SL; Hold GL; Lees CW, 2015, 'The Impact of NOD2 Variants on Gut Microbiota in Crohn's Disease and Healthy Controls', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, DC, Washington, pp. S718 - S718, presented at 46th Annual Digestive Disease Week (DDW), DC, Washington, 16 May 2015 - 19 May 2015,
    Conference Papers | 2015
    Mukhopadhya I; Berry S; Hunt A; Murdoch H; Smith-Palmer A; Hold GL, 2015, 'GENOTYPING OF ROTAVIRUS ISOLATES PRIOR TO THE INTRODUCTION OF THE ROTAVIRUS VACCINE IN SCOTLAND AND EARLY INDICATIONS OF THE IMPACT OF THE VACCINE', in GUT, BMJ PUBLISHING GROUP, ENGLAND, London, pp. A510 - A511, presented at 2nd Digestive-Disorders-Federation Conference, ENGLAND, London, 22 June 2015 - 25 June 2015,
    Conference Abstracts | 2015
    Mukhopadhya I; Berry S; Thomson J; Murray GI; El-Omar EM; Hold GL; Hijazi K, 2015, 'CHARACTERISATION OF DRUG TRANSPORTER GENE EXPRESSION IN COLORECTAL TISSUE AND CELL LINES: INDUCTION WITH ANTI-RETROVIRALS FOR MICROBICIDE OPTIMISATION', in GUT, BMJ PUBLISHING GROUP, ENGLAND, London, Vol. 64, pp. A173 - A174, presented at 2nd Digestive-Disorders-Federation Conference, ENGLAND, London, 22 June 2015 - 25 June 2015,
    Conference Papers | 2015
    Smith-Palmer A; Murdoch H; Hunt A; Mukhopadhya I; Hold G; Cameron C, 2015, 'Evaluating the impact of a national rotavirus vaccine programme on circulating strain types and identifying possible vaccine failures', in JOURNAL OF CLINICAL VIROLOGY, ELSEVIER SCIENCE BV, pp. S68 - S68,
    Conference Papers | 2014
    Adams AT; Kennedy NA; Hansen R; Ventham NT; O'Leary KR; Drummond HE; Noble CL; El-Omar E; Russell RK; Wilson DC; Nimmo ER; Hold GL; Satsangi J, 2014, 'GENOME-WIDE EPIGENETIC ANALYSIS IN CHILDHOOD-ONSET CROHN'S DISEASE IMPLICATES MIR21', in GUT, BMJ PUBLISHING GROUP, ENGLAND, Manchester, pp. A2 - A2, presented at Annual Meeting of the British-Society-of-Gastroenterology (BSG), ENGLAND, Manchester, 16 June 2014 - 19 June 2014,
    Conference Papers | 2014
    Jagger FA; Cameron FL; Loganathan S; Hold GL; Hansen R, 2014, 'Ten years of paediatric inflammatory bowel disease incidence in the north of Scotland', in JOURNAL OF CROHNS & COLITIS, ELSEVIER SCIENCE BV, pp. S400 - S400,
    Conference Papers | 2014
    Kennedy NA; Walker AW; Berry SH; Lamb CA; Lewis S; Mansfield J; Parkes M; Parkhill J; Probert C; Read D; Satsangi J; Simpkins R; Tomlinson D; Tremelling M; Nutland S; Hold GL; Lees CW, 2014, 'THE IMPACT OF NOD2 VARIANTS ON GUT MICROBIOTA IN CROHN'S DISEASE AND HEALTHY CONTROLS', in GUT, BMJ PUBLISHING GROUP, ENGLAND, Manchester, pp. A159 - S160, presented at Annual Meeting of the British-Society-of-Gastroenterology (BSG), ENGLAND, Manchester, 16 June 2014 - 19 June 2014,
    Conference Papers | 2014
    Lochhead PJ; Mayer C-D; Hold GL; El-Omar E, 2014, 'Genome-Wide Analysis of DNA Methylation in Low-Grade Colorectal Adenomas and Normal Colonic Mucosa', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, IL, Chicago, pp. S165 - S165, presented at 55th Annual Meeting of the Society-for-Surgery-of-the-Alimentary-Tract (SSAT) / Digestive Disease Week (DDW), IL, Chicago, 03 May 2014 - 06 May 2014,
    Conference Papers | 2014
    Mukhopadhya I; Berry S; El-Omar EM; Thomson J; Hold GL; Hijazi K, 2014, 'Characterisation of Drug Transporter Gene Expression in Colorectal Tissue and Cell Lines: Induction with Anti-retrovirals for Microbicide Optimization', in AIDS RESEARCH AND HUMAN RETROVIRUSES, MARY ANN LIEBERT, INC, SOUTH AFRICA, Cape Town, pp. A201 - A201, presented at Symposium on HIV Research for Prevention (HIV R4P), SOUTH AFRICA, Cape Town, 28 October 2014 - 31 October 2014,
    Conference Papers | 2014
    Smith KA; Mukhopadhya I; Berry S; Hold GL; Hijazi K, 2014, 'Expression of Drug Transporters in Cervicovaginal Cell Lines and Modulatory Effect of Candidate Antiretroviral Microbicides', in AIDS RESEARCH AND HUMAN RETROVIRUSES, MARY ANN LIEBERT, INC, SOUTH AFRICA, Cape Town, pp. A201 - A201, presented at Symposium on HIV Research for Prevention (HIV R4P), SOUTH AFRICA, Cape Town, 28 October 2014 - 31 October 2014,
    Conference Papers | 2013
    Hansen R; Berry S; Mukhopadhya I; Thomson J; Saunders K; Nicholl C; Bisset M; Russell R; El-Omar E; Hold G, 2013, 'THE MICROAEROPHILIC MICROBIOTA OF DE-NOVO PAEDIATRIC INFLAMMATORY BOWEL DISEASE: THE BISCUIT STUDY', in GUT, BMJ PUBLISHING GROUP, SCOTLAND, Glasgow, pp. A31 - A31, presented at Annual General Meeting of the British-Society-of-Gastroenterology, SCOTLAND, Glasgow, 24 June 2013 - 27 June 2013,
    Conference Papers | 2013
    Hansen R; Mukhopadhya I; Meharg C; Russell R; Berry S; El-Omar E; Hold G, 2013, 'THE ROLE OF THE FUNGAL MICROBIOTA IN THE PATHOGENESIS OF DE-NOVO PAEDIATRIC INFLAMMATORY BOWEL DISEASE USING NEXT GENERATION SEQUENCING', in GUT, BMJ PUBLISHING GROUP, SCOTLAND, Glasgow, pp. A32 - A32, presented at Annual General Meeting of the British-Society-of-Gastroenterology, SCOTLAND, Glasgow, 24 June 2013 - 27 June 2013,
    Conference Papers | 2013
    Hansen R; Mukhopadhya I; Meharg C; Russell RK; Berry SH; El-Omar E; Hold GL, 2013, 'The Role of the Fungal Microbiota in the Pathogenesis of De-Novo Pediatric Inflammatory Bowel Disease Using Next Generation Sequencing', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, FL, Orlando, pp. S826 - S826, presented at Digestive Disease Week / 28th Annual Residents and Fellows Research Conference of the Society-for-Surgery-of-the-Alimentary-Tract (SSAT), FL, Orlando, 18 May 2013 - 21 May 2013,
    Conference Papers | 2013
    Hold G; Hope M; Lochhead P; Meharg C; Berry S; El-Omar E, 2013, 'ASSESSMENT OF BACTERIAL DIVERSITY IN COLORECTAL ADENOMATOUS POLYPS', in GUT, BMJ PUBLISHING GROUP, SCOTLAND, Glasgow, pp. A134 - A135, presented at Annual General Meeting of the British-Society-of-Gastroenterology, SCOTLAND, Glasgow, 24 June 2013 - 27 June 2013,
    Conference Papers | 2013
    Hold GL; Hope M; Lochhead P; Meharg C; Berry SH; El-Omar E, 2013, 'Assessment of Bacterial Diversity in Colorectal Adenomatous Polyps', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, FL, Orlando, pp. S348 - S348, presented at Digestive Disease Week / 28th Annual Residents and Fellows Research Conference of the Society-for-Surgery-of-the-Alimentary-Tract (SSAT), FL, Orlando, 18 May 2013 - 21 May 2013,
    Conference Papers | 2013
    Kennedy NA; Walker A; Berry SH; Duncan SH; Farquharson F; Louis P; Satsangi J; Flint HJ; Lees CW; Hold GL, 2013, 'Evaluation of the Impact of Different Commercially Available DNA Extraction Kits and Laboratories for Assessing Bacterial Community Structure in Fecal Samples - Implications for IBD Research', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, FL, Orlando, pp. S829 - S829, presented at Digestive Disease Week / 28th Annual Residents and Fellows Research Conference of the Society-for-Surgery-of-the-Alimentary-Tract (SSAT), FL, Orlando, 18 May 2013 - 21 May 2013,
    Conference Papers | 2013
    Watt E; Berry S; Farquarson F; Glaire M; Thomson J; El-Omar E; Louis P; Hold G, 2013, 'EVALUATION OF FAECAL ASPIRATE AS A PROXY FOR COLONOSCOPY BIOPSY SAMPLING TO ASSESS MICROBIAL DIVERSITY', in GUT, BMJ PUBLISHING GROUP, SCOTLAND, Glasgow, pp. A135 - A135, presented at Annual General Meeting of the British-Society-of-Gastroenterology, SCOTLAND, Glasgow, 24 June 2013 - 27 June 2013,
    Conference Papers | 2013
    Watt E; Berry SH; Farquharson F; Glaire MA; Thomson JM; El-Omar E; Louis P; Hold GL, 2013, 'Evaluation of Fecal Aspirate As a Proxy for Colonoscopy Biopsy Sampling to Assess Microbial Diversity', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, FL, Orlando, pp. S832 - S832, presented at Digestive Disease Week / 28th Annual Residents and Fellows Research Conference of the Society-for-Surgery-of-the-Alimentary-Tract (SSAT), FL, Orlando, 18 May 2013 - 21 May 2013,
    Conference Papers | 2012
    Palmer AJ; Lochhead P; Hold GL; Rabkin CS; Vaughan TL; Lissowska J; Chow W-H; Berry SH; El-Omar E, 2012, 'Genetic Variation in C20orf54, PLCE1 and MUC1 and Risk of Upper Gastrointestinal Cancers in Caucasian Populations', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, CA, San Diego, pp. S634 - S634, presented at Digestive Disease Week (DDW), CA, San Diego, 19 May 2012 - 22 May 2012,
    Conference Papers | 2011
    Goddard M; Hansen R; Karcher AM; Munro MJ; Berry SH; Stevenson MH; El-Omar E; Hold GL, 2011, 'Bilirubin Has Anti-Bacterial Properties Against Gram-Positive Bacteria: A Potential Benefit of Physiological Jaundice?', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, IL, Chicago, pp. S941 - S941, presented at Conference on Digestive Disease Week 2011, IL, Chicago, 07 May 2011 - 10 May 2011,
    Conference Papers | 2011
    Hansen R; Mukhopadhya I; Russell RK; Bisset WM; Berry SH; Thomson JM; El-Omar EM; Hold GL, 2011, 'THE ROLE OF MICROAEROPHILIC COLONIC MUCOSAL BACTERIA IN DE NOVO PAEDIATRIC INFLAMMATORY BOWEL DISEASE', in GUT, B M J PUBLISHING GROUP, ENGLAND, Birmingham, pp. A147 - A147, presented at Annual Meeting on British-Society-of-Gasenterology, ENGLAND, Birmingham, 14 March 2011 - 17 March 2011,
    Conference Papers | 2011
    Hansen R; Mukhopadhya I; Russell RK; Bisset WM; Berry SH; Thomson JM; El-Ontar E; Hold GL, 2011, 'The Role of the Microaerophilic Colonic Microbiota in De-Novo Paediatric Inflammatory Bowel Disease', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, IL, Chicago, pp. S512 - S512, presented at Conference on Digestive Disease Week 2011, IL, Chicago, 07 May 2011 - 10 May 2011,
    Conference Papers | 2011
    Hansen R; Reiff C; Russell RK; Bisset WM; Berry SH; Mukhopadhya I; Thomson JM; El-Omar E; Hold GL, 2011, 'Bacterial Diversity of the Colonic Microbiota in De-Novo Extensive Paediatric Ulcerative Colitis by Next-Generation Sequencing', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, IL, Chicago, pp. S196 - S196, presented at Conference on Digestive Disease Week 2011, IL, Chicago, 07 May 2011 - 10 May 2011,
    Conference Papers | 2011
    Hansen R; Reiff C; Russell RK; Bisset WM; Berry SH; Mukhopadhya I; Thomson JM; El-Omar EM; Hold GL, 2011, 'COLONIC MUCOSAL BACTERIAL DIVERSITY OF DE NOVO EXTENSIVE PAEDIATRIC ULCERATIVE COLITIS BY NEXT-GENERATION SEQUENCING', in GUT, B M J PUBLISHING GROUP, ENGLAND, Birmingham, presented at Annual Meeting on British-Society-of-Gasenterology, ENGLAND, Birmingham, 14 March 2011 - 17 March 2011,
    Conference Papers | 2011
    Mukhopadhya I; Thomson JM; Hansen R; Alotaibi B; Berry SH; El-Omar EM; Hold GL, 2011, 'DETECTION OF CAMPYLOBACTER CONCISUS IN COLONIC BIOPSIES FROM ADULT PATIENTS WITH ULCERATIVE COLITIS', in GUT, B M J PUBLISHING GROUP, ENGLAND, Birmingham, pp. A211 - A211, presented at Annual Meeting on British-Society-of-Gasenterology, ENGLAND, Birmingham, 14 March 2011 - 17 March 2011,
    Conference Papers | 2011
    Mukhopadhya I; Thomson JM; Hansen R; Berry SH; El-Omar E; Hold GL, 2011, 'Detection of Campylobacter Concisus in Colonic Biopsies From Adult Patients With Ulcerative Colitis', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, IL, Chicago, pp. S268 - S268, presented at Conference on Digestive Disease Week 2011, IL, Chicago, 07 May 2011 - 10 May 2011,
    Conference Papers | 2010
    Basavaraju U; Shebl F; Palmer AJ; Hold GL; Rabkin CS; El-Omar EM, 2010, 'CYTOKINE GENE POLYMORPHISMS, CYTOKINE LEVELS AND RISK OF COLORECTAL NEOPLASIA IN THE SCREENED POPULATION OF NORTHEAST SCOTLAND', in GUT, B M J PUBLISHING GROUP, ENGLAND, Liverpool, pp. A44 - A45, presented at Annual General Meeting of the British-Society-of-Gastroenterology, ENGLAND, Liverpool, 22 March 2010 - 25 March 2010,
    Conference Papers | 2010
    Basavaraju U; Shebl FM; Palmer AJ; Hold GL; Rabkin CS; El-Omar E, 2010, 'Cytokine Gene Polymorphisms, Cytokine Levels and Risk of Colorectal Neoplasia in the Screened Population of Northeast Scotland', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, pp. S613 - S613,
    Conference Papers | 2010
    El-Sakka NE; Hold GL; El-Omar E, 2010, 'Role of TLR4 in Carcinogenesis and Tumor Progression of Colorectal Cancer', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, pp. S730 - S730,
    Conference Papers | 2010
    FitzGerald MP; Wehmeier S; Gangloff M; Gay N; Berry SH; Ferguson GP; El-Omar E; Hold GL, 2010, 'Can Helicobacter pylori Lipopolysaccharide Lipid a Composition Affect Its Ability to Induce an Inflammatory Response Through Toll Like Receptor 4', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, pp. S244 - S244,
    Conference Papers | 2010
    FitzGerald MP; Wehmeier S; Gangloff M; Gay N; Berry SH; Ferguson GP; El-Omar EM; Hold GL, 2010, 'CAN HELICOBACTER PYLORI LIPOPOLYSACCHARIDE LIPID A COMPOSITION AFFECT ITS ABILITY TO INDUCE AN INFLAMMATORY RESPONSE THROUGH TOLL-LIKE RECEPTOR 4', in GUT, B M J PUBLISHING GROUP, ENGLAND, Liverpool, pp. A22 - A22, presented at Annual General Meeting of the British-Society-of-Gastroenterology, ENGLAND, Liverpool, 22 March 2010 - 25 March 2010,
    Conference Papers | 2010
    Hold G; El-Omar E; Chow W; Risch H; Gammon M; Vaughan T; Lissowska J; Lochhead P; Rabkin C; Ng M, 2010, 'ASSESSMENT OF NOVEL GENETIC POLYMORPHISMS AND RISK OF UPPER GASTROINTESTINAL CARCINOMA', in GUT, B M J PUBLISHING GROUP, ENGLAND, Liverpool, pp. A21 - A22, presented at Annual General Meeting of the British-Society-of-Gastroenterology, ENGLAND, Liverpool, 22 March 2010 - 25 March 2010,
    Conference Papers | 2010
    Ng MT; Lochhead P; Lissowska J; Vaughan TL; Gammon M; Risch H; Chow W-H; Hold GL; El-Omar E, 2010, 'Assessment of Novel Genetic Polymorphisms and Risk of Upper Gastrointestinal Carcinoma', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, pp. S612 - S612,
    Conference Papers | 2010
    Saunders KA; Crockett JC; Berry SH; El-Omar E; Hold GL, 2010, 'Impact of the TLR4 Asp299Gly Polymorphism on Induction of the Inflammatory Response Following H. pylori Infection', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, pp. S244 - S244,
    Conference Papers | 2010
    Saunders KA; Crockett JC; Berry SH; El-Omar EM; Hold GL, 2010, 'IMPACT OF THE TLR4 ASP299GLY POLYMORPHISM ON INDUCTION OF THE INFLAMMATORY RESPONSE FOLLOWING HELICOBACTER PYLORI INFECTION', in GUT, B M J PUBLISHING GROUP, ENGLAND, Liverpool, pp. A20 - A20, presented at Annual General Meeting of the British-Society-of-Gastroenterology, ENGLAND, Liverpool, 22 March 2010 - 25 March 2010,
    Conference Papers | 2009
    Hansen R; El-Sakka NE; Berry SH; Thomson JM; Bisset WM; Mahdi G; Murray GI; Helms PJ; Hold G; El-Omar EM, 2009, 'Are Non-Pylori Helicobacter Organisms Associated with Paediatric Ulcerative Colitis? Retrospective Observational Study', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, IL, Chicago, pp. A671 - A671, presented at Digestive Disease Week/110th Annual Meeting of the American-Gastroenterological-Association, IL, Chicago, 30 May 2009 - 04 June 2009,
    Conference Papers | 2008
    Thomson JM; Louis P; Hold GL; Mowat NG; Flint HJ; El-Omar EM, 2008, 'Changes in the mucosally adherent microbial community in ulcerative colitis', in GUT, B M J PUBLISHING GROUP, ENGLAND, Brimingham, pp. A150 - A150, presented at Annual General Meeting of the British-Society-of-Gastroenterology, ENGLAND, Brimingham, 10 March 2008 - 13 March 2008,
    Conference Papers | 2007
    Hold G; Berry S; Perez-perez GI; El-omar EM, 2007, 'Effect of the TLR4 Asp299gly polymorphism on LPS-induced cytokine production and Nf-kappa B activation in mononuclear cells', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, DC, Washington, pp. A217 - A218, presented at Digestive Disease Weeking Meeting/ASGE Postgraduate Course Meeting, DC, Washington, 19 May 2007 - 24 May 2007,
    Conference Papers | 2007
    Hold G; Berry S; Rabkin C; Chow W-H; Fraumeni J; Mowat A; Ando T; Goto H; El-omar EM, 2007, 'Tlr9-1237t/C promoter polymorphism and risk of gastric cancer in Caucasian and Japanese populations', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, DC, Washington, pp. A218 - A218, presented at Digestive Disease Weeking Meeting/ASGE Postgraduate Course Meeting, DC, Washington, 19 May 2007 - 24 May 2007,
    Conference Papers | 2007
    McLean MH; Murray GI; Fyfe N; Hold GL; Mowat AG; El-Omar EM, 2007, 'Assessment of inflammatory cell phenotype in sporadic hyperplastic polyps', in GUT, B M J PUBLISHING GROUP, SCOTLAND, Glasgow, pp. A51 - A51, presented at Annual Meeting of the British-Society-of-Gastroenterology, SCOTLAND, Glasgow, 26 March 2007 - 29 March 2007,
    Conference Papers | 2007
    McLean MH; Murray GI; Fyfe N; Hold GL; Mowat AG; El-Omar EM, 2007, 'Assessment of macrophage function within the stroma of sporadic colorectal polyps', in GUT, B M J PUBLISHING GROUP, SCOTLAND, Glasgow, pp. A51 - A51, presented at Annual Meeting of the British-Society-of-Gastroenterology, SCOTLAND, Glasgow, 26 March 2007 - 29 March 2007,
    Conference Papers | 2007
    Mclean MH; Murray GI; Stewart KN; Hold GL; Fyfe N; Mowat NAG; El-Omar EM, 2007, 'Role of chronic inflammation in sporadic colorectal neoplasia', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, DC, Washington, pp. A305 - A306, presented at Digestive Disease Weeking Meeting/ASGE Postgraduate Course Meeting, DC, Washington, 19 May 2007 - 24 May 2007,
    Conference Papers | 2007
    Smith MG; Hold G; Rabkin C; Chow W-H; Fraumeni J; Mowat A; El-omar EM, 2007, 'A COX-2 gene polymorphism increases risk of non-cardia gastric cancer and esophageal squamous cancer in a US population', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, DC, Washington, pp. A217 - A217, presented at Digestive Disease Weeking Meeting/ASGE Postgraduate Course Meeting, DC, Washington, 19 May 2007 - 24 May 2007,
    Conference Papers | 2006
    Cooper IAM; Thomson JM; Hold GL; Smith MG; Fyfe N; Mowat NAG; Shen Z; Fox JG; El-Omar EM, 2006, 'Detection of Helicobacter species in archival human ulcerative colitis tissue by fluorescent in situ hybridisation', in GUT, B M J PUBLISHING GROUP, ENGLAND, Birmingham, pp. A77 - A77, presented at Annual Meeting of the British-Society-of-Gastroenterology, ENGLAND, Birmingham, 20 March 2006 - 23 March 2006,
    Conference Papers | 2006
    Hold GL; Smith MG; Berry SH; McColl KE; El-Omar EM, 2006, 'Innate immune response gene polymorphisms and their role in H pylori induced precancerous changes', in GUT, B M J PUBLISHING GROUP, ENGLAND, Birmingham, pp. A26 - A27, presented at Annual Meeting of the British-Society-of-Gastroenterology, ENGLAND, Birmingham, 20 March 2006 - 23 March 2006,
    Conference Papers | 2006
    Hold GL; Smith MG; McLean MH; Berry S; McColl KE; Mowat A; El-Omar EM, 2006, 'Innate immune response gene polymorphisms and their role in H-pylori-induced gastric cancer', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, CA, Los Angeles, pp. A61 - A61, presented at Digestive Disease Week/107th Annual Meeting of the American-Gastroenterological-Association, CA, Los Angeles, 19 May 2006 - 24 May 2006,
    Conference Papers | 2006
    Hope ME; Hold GL; Berry S; Ashley M; El-Omar EM, 2006, 'Assessment of microbial diversity in neoplastic colonic tissue', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, CA, Los Angeles, pp. A371 - A371, presented at Digestive Disease Week/107th Annual Meeting of the American-Gastroenterological-Association, CA, Los Angeles, 19 May 2006 - 24 May 2006,
    Conference Papers | 2006
    McLean MH; Murray GI; Fyfe N; Hold GL; Mowat NAG; El-Omar EM, 2006, 'Assessment of inflammation within sporadic colorectal polyps', in GUT, B M J PUBLISHING GROUP, ENGLAND, Birmingham, pp. A23 - A23, presented at Annual Meeting of the British-Society-of-Gastroenterology, ENGLAND, Birmingham, 20 March 2006 - 23 March 2006,
    Conference Papers | 2006
    McLean MH; Murray GI; Fyfe N; Hold GL; Mowat NAG; El-Omar EM, 2006, 'Expression of cyclooxygenase-2 in human sporadic colorectal adenomas', in GUT, B M J PUBLISHING GROUP, ENGLAND, Birmingham, pp. A23 - A24, presented at Annual Meeting of the British-Society-of-Gastroenterology, ENGLAND, Birmingham, 20 March 2006 - 23 March 2006,
    Conference Papers | 2006
    Thomson J; Cooper I; Hold G; Fyfe N; Smith M; Mowat A; Shen Z; Fox JG; El-Omar E, 2006, 'Detection of Helicobacter species in archival human UC tissue by fluorescent in-situ hybridisation (FISH)', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, CA, Los Angeles, pp. A361 - A361, presented at Digestive Disease Week/107th Annual Meeting of the American-Gastroenterological-Association, CA, Los Angeles, 19 May 2006 - 24 May 2006,
    Conference Papers | 2005
    Cooper IAM; Hold GL; Shen Z; Fox JG; El-Omar EM, 2005, 'Development of a Helicobacter genus DNA probe for fluorescent in situ hybridization in gastrointestinal clinical samples', in HELICOBACTER, BLACKWELL PUBLISHING, DENMARK, Copenhagen, pp. 520 - 520, presented at 18th International Workshop on Gastrointestinal Pathology and Helicobactor, DENMARK, Copenhagen, 12 October 2005 - 14 October 2005,
    Conference Papers | 2005
    Cooper IAM; Hold GL; Smith MG; Vijayan B; Fyfe N; Shen Z; Fox JG; El-Omar EM, 2005, 'Detection of Helicobacter species in archival human UC colorectal tissue by fluorescent in situ hybridization (FISH)', in HELICOBACTER, BLACKWELL PUBLISHING, DENMARK, Copenhagen, pp. 549 - 549, presented at 18th International Workshop on Gastrointestinal Pathology and Helicobactor, DENMARK, Copenhagen, 12 October 2005 - 14 October 2005,
    Conference Papers | 2005
    Hold GL; Smith MG; Macarthur M; McLean MH; Hope M; Berry S; Mowat NAG; McColl KE; El-Omar EM, 2005, 'A COX-2 promoter polymorphism increases the risk of developing pre-malignant changes in a population of healthy first-degree gastric carcinoma realtives.', in GASTROENTEROLOGY, W B SAUNDERS CO, IL, Chicago, pp. A19 - A20, presented at Annual Meeting of the American-Gastroenterological-Association/Digestive-Disease-Week, IL, Chicago, 14 May 2005 - 19 May 2005,
    Conference Papers | 2005
    Hope ME; Hold GL; Berry S; Cooper I; Mowat A; El-Omar E, 2005, 'Assessment of microbial diversity in healthy colonic tissue', in GASTROENTEROLOGY, W B SAUNDERS CO, IL, Chicago, pp. A195 - A195, presented at Annual Meeting of the American-Gastroenterological-Association/Digestive-Disease-Week, IL, Chicago, 14 May 2005 - 19 May 2005,
    Conference Papers | 2005
    Nabi G; Hold GL; Cash P; Booth IR; N'Dow J, 2005, 'The role of mucus and protein biomarkers in intestinal segments transposed into the urinary tract', in BJU INTERNATIONAL, BLACKWELL PUBLISHING, pp. 43 - 43,
    Conference Papers | 2005
    Smith MG; Hold GL; MacArthur M; McLean M; Hope ME; Mowat NAG; McColl KE; El-Omar EM, 2005, 'COX-2 gene polymorphisms and association with premalignant changes in the stomach', in GUT, BMJ PUBLISHING GROUP, ENGLAND, Birmingham, pp. A9 - A10, presented at Annual Meeting of the British-Society-of-Gastroenterology, ENGLAND, Birmingham, 14 March 2005 - 17 March 2005,
    Conference Papers | 2005
    Smith MG; Hold GL; Rabkin C; Chow WH; Fraumeni JF; Ashley I; Mowat G; Ando T; Goto H; El-Omar EM, 2005, 'The interleukin-8-251 prometer polymorphism and risk of gastric cancer in Caucasian and Japanese populations.', in GASTROENTEROLOGY, W B SAUNDERS CO, IL, Chicago, pp. A19 - A19, presented at Annual Meeting of the American-Gastroenterological-Association/Digestive-Disease-Week, IL, Chicago, 14 May 2005 - 19 May 2005,
    Conference Papers | 2005
    Smith MG; Hold GL; Rabkin C; Chow WH; Fraumeni JF; Mowat NAG; Ando T; Goto H; El-Omar EM, 2005, 'IL-8-251 promoter polymorphism and risk of gastric cancer in white and Japanese populations', in GUT, BMJ PUBLISHING GROUP, ENGLAND, Birmingham, pp. A9 - A9, presented at Annual Meeting of the British-Society-of-Gastroenterology, ENGLAND, Birmingham, 14 March 2005 - 17 March 2005,
    Conference Papers | 2004
    Hold GL; Smith MG; Chow WH; Rabkin CS; El-Omar EM, 2004, 'A functional toll like receptor 4 polymorphism increases risk of gastric cancer', in GUT, B M J PUBLISHING GROUP, Scotland, Glasgow, pp. A23 - A23, presented at Annual Meeting of the British-Society-of-Gastroenterology, Scotland, Glasgow, 21 March 2004 - 24 March 2004,
    Conference Papers | 2004
    Hold GL; Smith MG; Chow WH; Rabkin CS; Fraumeni JF; El-Omar EM, 2004, 'A functional Toll-like receptor 4 polymorphism increases the risk of gastric cancer', in GASTROENTEROLOGY, W B SAUNDERS CO, LA, New Orleans, pp. A531 - A532, presented at Digestive Disease Week/105th Annual Meeting of the American-Gastroenterological-Association, LA, New Orleans, 16 May 2004 - 19 May 2004,
    Conference Papers | 2004
    Hope M; Hold GL; Kain R; El-Omar EM, 2004, 'Microbial diversity and carbohydrate expression in healthy and neoplastic colonic tissue', in GUT, B M J PUBLISHING GROUP, Scotland, Glasgow, pp. A68 - A68, presented at Annual Meeting of the British-Society-of-Gastroenterology, Scotland, Glasgow, 21 March 2004 - 24 March 2004,
    Conference Papers | 2004
    MacArthur M; Sharp L; Hold GL; Little J; El-Omar EM, 2004, 'Role of cytokine gene polymorphisms in colorectal cancer and their interaction with aspirin use', in GASTROENTEROLOGY, W B SAUNDERS CO, LA, New Orleans, pp. A243 - A243, presented at Digestive Disease Week/105th Annual Meeting of the American-Gastroenterological-Association, LA, New Orleans, 16 May 2004 - 19 May 2004,
    Conference Papers | 2004
    Macarthur M; Sharp L; Hold GL; Little J; El-Omar EM, 2004, 'Role of cytokine gene polymorphisms in colorectal cancer and their interaction with aspirin use in the north east of Scotland', in GUT, B M J PUBLISHING GROUP, Scotland, Glasgow, pp. A17 - A17, presented at Annual Meeting of the British-Society-of-Gastroenterology, Scotland, Glasgow, 21 March 2004 - 24 March 2004,
    Conference Papers | 2004
    Smith MG; Hold GL; Rabkin CS; Chow WH; McColl KEL; Perez-Perez GI; Mowat A; El-Omar EM, 2004, 'The IL-8-251 promoter polymorphism is associated with high IL-8 production, severe inflammation and increased risk of pre-malignant changes in H-pylori positive subjects', in GASTROENTEROLOGY, W B SAUNDERS CO, LA, New Orleans, pp. A23 - A23, presented at Digestive Disease Week/105th Annual Meeting of the American-Gastroenterological-Association, LA, New Orleans, 16 May 2004 - 19 May 2004,
    Conference Papers | 2003
    Hold GL; Smith M; McColl KE; El-Omar EM, 2003, 'A functional toll-like receptor 4 polymorphism increases risk of H-pylori-induced premalignant changes', in GASTROENTEROLOGY, W B SAUNDERS CO, FLORIDA, ORLANDO, pp. A19 - A20, presented at Digestive Disease Week 2003 Meeting/104th Annual Meeting of the American-Gastroenterological-Association, FLORIDA, ORLANDO, 17 May 2003 - 22 May 2003,
    Conference Papers | 2003
    Troost E; Hold GL; Smith MG; Mowat A; McColl KE; El-Omar EM, 2003, 'Gastric cancer relatives have a high prevalence of IL-18 and TGF-B1 proinflammatory genotypes', in GASTROENTEROLOGY, W B SAUNDERS CO, FLORIDA, ORLANDO, pp. A6 - A6, presented at Digestive Disease Week 2003 Meeting/104th Annual Meeting of the American-Gastroenterological-Association, FLORIDA, ORLANDO, 17 May 2003 - 22 May 2003,
    Conference Papers | 2002
    Garza-Gonzalez E; Hold GL; Perez-Perez GI; Bosques-Padilla FJ; Tijerina-Menchaca R; El-Omar EM, 2002, 'Role of the polymorphic cytokines genes in gastric cancer in Mexico', in GUT, BRITISH MED JOURNAL PUBL GROUP, GREECE, ATHENS, pp. A23 - A23, presented at 15th International Workshop on Gastrointestinal Pathology and Helicobacter, GREECE, ATHENS, 11 September 2002 - 14 September 2002,
    Conference Papers | 2002
    Troost E; Hold GL; Smith M; Chow WH; Rabkin CS; McColl KEL; El-Omar EM, 2002, 'Role of interleukin-1 beta and other potential genetic markers as indicators of gastric cancer risk', in Hunt RH; Tytgat GNJ (ed.), HELICOBACTER PYLORI: BASIC MECHANISMS TO CLINICAL CURE 2002, SPRINGER, HI, Maui, pp. 215 - 223, presented at 5th Symposium on Helicobacter Pylori - Basic Mechanisms to Clinical Care, HI, Maui, 10 November 2002 - 13 November 2002,

Dates

Award holder(s)

Funding body

Title

Value

2019-2022

Hold, G.L. and El-Omar, E.

Crohns and Colitis Australia

Understanding changes in the gut microbiota following therapeutic intervention in IBD

$75,000

2018/2019

Leong, R., Hold, G.L. /Sydney+ IBD research consortia

GESA (Australian Gastroenterology Society)

The Australian IBD Microbiome Study

$50,000

2018/2019

Lemberg, D., Leach, S., Hold, G.L. and Dutt, S.

Sydney Childrens Hospital Network

The Australian IBD Microbiome Study

$20,000


Fulbright Scholar, Harvard T. H. Chan School of Public Health, Boston (2014-2015)

Senior Fellow of the UK Higher Education Academy (2017)

My research focusses on understanding the impact of gastrointestinal microbes on human health and disease, with a specialist interest in inflammatory bowel disease. Developing greater understanding in this area allows us to further appreciate the contribution that gut microbes play in diseases and potentially develop therapeutic strategies to maintain and restore health. My lab has an internationally renowned reputation for microbiome analysis and host:microbial interactions. This has been achieved by a) developing robust protocols for collecting and processing the most clinically relevant samples, and b) ensuring the science is clinically driven.The main challenges in gut microbiome research relate to: 1) defining the point at which microbiota changes occur, which is in advance of clinical symptoms/disease presentation, 2) understanding the metabolic capabilities of the gut microbiota, 3) the effect of therapeutic regimens on the gut microbiota and ultimately identifying how to manipulate these factors to promote/maintain health. This requires multi-disciplinary research strategies harnessing clinicians, microbiologists, nutritionists, epidemiologists, bioinformaticians and also public health analysts. To achieve this, I collaborate with groups all over the world to ensure the skills sets required to address these multi-faceted research questions are brought together.

My Research Supervision

3 PhD students in areas relating to IBD, pregnancy and the microbiota