Dr Chris Jolly

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Journal articles | 2024

Truong P; Shen S; Joshi S; Islam MI; Zhong L; Raftery MJ; Afrasiabi A; Alinejad-Rokny H; Nguyen M; Zou X; Bhuyan GS; Sarowar CH; Ghodousi ES; Stonehouse O; Mohamed S; Toscan CE; Connerty P; Kakadia PM; Bohlander SK; Michie KA; Larsson J; Lock RB; Walkley CR; Thoms JAI; Jolly CJ; Pimanda JE, 2024, 'TOPORS E3 ligase mediates resistance to hypomethylating agent cytotoxicity in acute myeloid leukemia cells', Nature Communications, 15, pp. 7360,

Journal articles | 2023

Moles E; Howard CB; Huda P; Karsa M; McCalmont H; Kimpton K; Duly A; Chen Y; Huang Y; Tursky ML; Ma D; Bustamante S; Pickford R; Connerty P; Omari S; Jolly CJ; Joshi S; Shen S; Pimanda JE; Dolnikov A; Cheung LC; Kotecha RS; Norris MD; Haber M; de Bock CE; Somers K; Lock RB; Thurecht KJ; Kavallaris M; Moles Meler E, 2023, 'Delivery of PEGylated liposomal doxorubicin by bispecific antibodies improves treatment in models of high-risk childhood leukemia', Science translational medicine, 15, pp. eabm1262 - eabm1262,

Journal articles | 2023

Schnegg-Kaufmann AS; Thoms JAI; Bhuyan GS; Hampton HR; Vaughan L; Rutherford K; Kakadia PM; Lee HM; Johansson Beves EMV; Failes TW; Arndt GM; Koval J; Lindeman R; Warburton P; Rodriguez-Meira A; Mead AJ; Unnikrishnan A; Davidson S; Polizzotto MN; Hertzberg M; Papaemmanuil E; Bohlander SK; Faridani OR; Jolly CJ; Zanini F; Pimanda JE, 2023, 'Contribution of mutant HSC clones to immature and mature cells in MDS and CMML, and variations with AZA therapy', Blood, 141, pp. 1316 - 1321,

Journal articles | 2022

Michel AO; Donovan TA; Roediger B; Lee Q; Jolly CJ; Monette S, 2022, 'Chaphamaparvovirus antigen and nucleic acids are not detected in kidney tissues from cats with chronic renal disease or immunocompromised cats', Veterinary Pathology, 59, pp. 120 - 126,

Journal articles | 2022

O’Rourke MB; Roediger BR; Jolly CJ; Crossett B; Padula MP; Hansbro PM, 2022, 'Viral Biomarker Detection and Validation Using MALDI Mass Spectrometry Imaging (MSI)', Proteomes, 10,

Journal articles | 2022

Schnegg-Kaufmann A; Thoms J; Bhuyan GS; Henry H; Vaughan L; Rutherford K; Kakadia P; Johansson E; Failes T; Greg A; Koval J; Lindeman R; Warburton P; Rodriguez-Meira A; Mead A; Unnikrishnan A; Bohlander S; Pappaemmanuil E; Faridani O; Jolly C; Zanini F; Pimanda J, 2022, 'P748: SINGLE CELL GENOTYPING OF MATCHED BONE MARROW AND PERIPHERAL BLOOD CELLS IN TREATMENT NAIVE AND AZA-TREATED MDS AND CMML', HemaSphere, 6, pp. 643 - 644,

Journal articles | 2022

Thoms JAI; Schnegg-Kaufmann A; Bhuyan GS; Hampton HR; Vaughan L; Rutherford K; Kakadia PM; Lee HM; Johansson E; Failes TW; Arndt GM; Koval J; Davidson S; Lindeman R; Warburton P; Rodriguez-Meira A; Mead AJ; Unnikrishnan A; Hertzberg M; Polizzotto MN; Papaemmanuil E; Bohlander SK; Faridani O; Jolly CJ; Zanini F; Pimanda JE, 2022, 'Clinical Response to Azacytidine (AZA) Is Associated with Increased Contribution from Mutated Blood Progenitors: Insights from Single Cell Genotyping of Matched Stem/Progenitor and Mature Blood Cells from MDS/CMML Patients Pre- and Post-AZA Treatment', Blood, 140, pp. 9751 - 9752,

Journal articles | 2022

Truong P; Shen S; Joshi S; Afrasiabi A; Zhong L; Raftery MJ; Larsson J; Lock RB; Walkley CR; Rokny HA; Thoms JAI; Jolly CJ; Pimanda JE, 2022, 'Genome-Wide CRISPR-Cas9 Screening Identifies a Synergy between Hypomethylating Agents and Sumoylation Blockade in Myelodysplastic Syndromes and Acute Myeloid Leukemia', BLOOD, 140,

Journal articles | 2020

Jolly CJ; Pimanda JE, 2020, 'Titans awake: HMAs for virus-driven ATL', Blood, 136, pp. 777 - 779,

Journal articles | 2020

Lee Q; Padula MP; Pinello N; Williams SH; O’Rourke MB; Fumagalli MJ; Orkin JD; Song R; Shaban B; Brenner O; Pimanda JE; Weninger W; de Souza WM; Melin AD; Wong JJL; Crim MJ; Monette S; Roediger B; Jolly CJ, 2020, 'Murine and related chapparvoviruses are nephro-tropic and produce novel accessory proteins in infected kidneys', PLoS Pathogens, 16, pp. e1008262,

Journal articles | 2019

Gall MG; Zhang HE; Lee Q; Jolly CJ; McCaughan GW; Cook A; Roediger B; Gorrell MD, 2019, 'Immune regeneration in irradiated mice is not impaired by the absence of DPP9 enzymatic activity', Scientific Reports, 9, pp. 7292,

Journal articles | 2019

Jolly C; Lee Q; Padula M; Pinello N; Williams S; O’Rourke M; Fumagalli MJ; Orkin J; Shaban B; Brenner O; Weninger W; de Souza WM; Melin A; Wong JJ-L; Crim M; Monette S; Roediger B, 2019, 'MKPV (aka MuCPV) and related chapparvoviruses are nephro-tropic and encode novel accessory proteins p15 and NS2', ,

Journal articles | 2019

Poyntz HC; Jones A; Jauregui R; Young W; Gestin A; Mooney A; Lamiable O; Altermann E; Schmidt A; Gasser O; Weyrich L; Jolly CJ; Linterman MA; Gros GL; Hawkins ED; Forbes-Blom E, 2019, 'Genetic regulation of antibody responsiveness to immunization in substrains of BALB/c mice', Immunology and Cell Biology, 97, pp. 39 - 53,

Journal articles | 2018

Jolly C; Gall M; Gorrell M; Cook A; Roediger B; Zhang HE; McCaughan G, 2018, 'Immune regeneration in irradiated mice is not impaired by the absence of DPP9 enzymatic activity [forthcoming publication]', Forthcoming/preprint available in bioRxiv,

Journal articles | 2018

Roediger B; Lee Q; Tikoo S; Cobbin JCA; Henderson JM; Jormakka M; O'Rourke MB; Padula MP; Pinello N; Henry M; Wynne M; Santagostino SF; Brayton CF; Rasmussen L; Lisowski L; Tay SS; Harris DC; Bertram JF; Dowling JP; Bertolino P; Lai JH; Wu W; Bachovchin WW; Wong JJL; Gorrell MD; Shaban B; Holmes EC; Jolly CJ; Monette S; Weninger W, 2018, 'An Atypical Parvovirus Drives Chronic Tubulointerstitial Nephropathy and Kidney Fibrosis', Cell, 175, pp. 530 - 543.e24,

Journal articles | 2018

Thientosapol ES; Bosnjak D; Durack T; Stevanovski I; Van Geldermalsen M; Holst J; Jahan Z; Shepard C; Weninger W; Kim B; Brink R; Jolly CJ, 2018, 'SAMHD1 enhances immunoglobulin hypermutation by promoting transversion mutation', Proceedings of the National Academy of Sciences of the United States of America, 115, pp. 4921 - 4926,

Journal articles | 2017

Thientosapol ES; Sharbeen G; Edwin Lau KK; Bosnjak D; Durack T; Stevanovski I; Weninger W; Jolly CJ, 2017, 'Proximity to AGCT sequences dictates MMR-independent versus MMR-dependent mechanisms for AID-induced mutation via UNG2', Nucleic Acids Research, 45, pp. 3146 - 3157,

Journal articles | 2017

Wang XM; Holz LE; Chowdhury S; Cordoba SP; Evans KA; Gall MG; De Ribeiro AJV; Zheng YZ; Levy MT; Yu DMT; Yao TW; Polak N; Jolly CJ; Bertolino P; McCaughan GW; Gorrell MD, 2017, 'The pro-fibrotic role of dipeptidyl peptidase 4 in carbon tetrachloride-induced experimental liver injury', Immunology and Cell Biology, 95, pp. 443 - 453,

Journal articles | 2014

Chang GH; Lay AJ; Ting KK; Zhao Y; Coleman PR; Powter EE; Formaz-Preston A; Jolly CJ; Bower NI; Hogan BM; Rinkwitz S; Becker TS; Vadas MA; Gamble JR, 2014, 'Arhgap18: An endogenous inhibitor of angiogenesis, limiting tip formation and stabilizing junctions', Small GTPases, 5,

Journal articles | 2012

Chan TD; Wood K; Hermes JR; Jolly CJ; Basten A; Brink R, 2012, 'Elimination of germinal-center-derived self-reactive B cells is governed by the location and concentration of self-antigen', Immunity, 37, pp. 893 - 904,

Journal articles | 2012

Sharbeen G; Yee CWY; Smith AL; Jolly CJ, 2012, 'Ectopic restriction of DNA repair reveals that UNG2 excises AID-induced uracils predominantly or exclusively during G1 phase', Journal of Experimental Medicine, 209, pp. 965 - 974,

Journal articles | 2010

Sharbeen G; Cook AJL; Lau KKE; Raftery J; Yee CWY; Jolly CJ, 2010, 'Incorporation of dUTP does not mediate mutation of A:T base pairs in Ig genes in vivo', Nucleic Acids Research, 38, pp. 8120 - 8130,

Journal articles | 2008

Jolly CJ; Cook AJL; Manis JP, 2008, 'Fixing DNA breaks during class switch recombination', Journal of Experimental Medicine, 205, pp. 509 - 513,

Journal articles | 2007

Cook AJL; Raftery JM; Lau KKE; Jessup A; Harris RS; Takeda S; Jolly CJ, 2007, 'DNA-dependent protein kinase inhibits AID-induced antibody gene conversion', PLoS Biology, 5, pp. 792 - 799,

Journal articles | 2007

Jolly C; Cook AJL; Raferty J; Jones ME, 2007, 'Measuring bidirectional mutation', Journal of Theoretical Biology, 246, pp. 269 - 277,

Journal articles | 2007

Jolly C; Cook AJL; Raftery J; Jones ME, 2007, 'Corrigendum to "Measuring bidirectional mutation". [J. Theor. Biol. 246 (2006) 269-277] (DOI:10.1016/j.jtbi.2006.12.034)', Journal of Theoretical Biology, 247, pp. 862,

Journal articles | 2003

Cook AJL; Oganesian L; Harumal P; Basten A; Brink R; Jolly CJ, 2003, 'Reduced Switching in SCID B Cells Is Associated with Altered Somatic Mutation of Recombined S Regions', Journal of Immunology, 171, pp. 6556 - 6564,

Journal articles | 2001

Jolly CJ; Neuberger MS, 2001, 'Somatic hypermutation of immunoglobulin κ transgenes: Association of mutability with demethylation', Immunology and Cell Biology, 79, pp. 18 - 22,

Journal articles | 2000

Neuberger MS; Sale JE; Cumbers SJ; Jolly CJ; Bemark MP; Ehrenstein MR; Lanoue A; Brüggemann M; Batista FD; Davies SL; Williams GT, 2000, 'Diversification and selection mechanisms for the production of protein repertoires: Lessons from the immune system', Applied Biochemistry and Biotechnology - Part A Enzyme Engineering and Biotechnology, 83, pp. 53 - 62,

Journal articles | 2000

Williams GT; Jolly CJ; Köhler J; Neuberger MS, 2000, 'The contribution of somatic hypermutation to the diversity of serum immunoglobulin: Dramatic increase with age', Immunity, 13, pp. 409 - 417,

Journal articles | 1998

Klix N; Jolly CJ; Davies SL; Brüggemann M; Williams GT; Neuberger MS, 1998, 'Multiple sequences from downstream of the J(κ) cluster can combine to recruit somatic hypermutation to a heterologous, upstream mutation domain', European Journal of Immunology, 28, pp. 317 - 326, http://dx.doi.org/10.1002/(SICI)1521-4141(199801)28:01<317::AID-IMMU317>3.0.CO;2-S

Journal articles | 1998

Neuberger MS; Ehrenstein MR; Klix N; Jolly CJ; Yélamos J; Rada C; Milstein C, 1998, 'Monitoring and interpreting the intrinsic features of somatic hypermutation', Immunological Reviews, 162, pp. 107 - 116,

Journal articles | 1997

Jolly CJ; Klix N; Neuberger MS, 1997, 'Rapid methods for the analysis of immunoglobulin gene hypermutation: Application to transgenic and gene targeted mice', Nucleic Acids Research, 25, pp. 1913 - 1919,

Journal articles | 1997

Jolly CJ; O'Neill HC, 1997, 'Specific transcription of the unrearranged TCR Vβ8.2 gene in lymphoid tissues occurs independently of V(D)J rearrangement', Immunology and Cell Biology, 75, pp. 13 - 20,

Journal articles | 1996

Jolly CJ; Glenn GM; Rahman S, 1996, 'GSP-1 genes are linked to the grain hardness locus (Ha) on wheat chromosome 5D', Proceedings of the National Academy of Sciences of the United States of America, 93, pp. 2408 - 2413,

Journal articles | 1996

Jolly CJ; Wagner SD; Rada C; Klix N; Milstein C; Neuberger MS, 1996, 'The targeting of somatic hypermutation', Seminars in Immunology, 8, pp. 159 - 168,

Journal articles | 1995

Jolly CJ; O'neill HC, 1995, 'Expression of a TCR Vβ8.2 polypeptide from the unrearranged gene in a murine lymphoid precursor cell line', International Immunology, 7, pp. 1147 - 1156,

Journal articles | 1995

O'Neill HC; Jolly CJ, 1995, 'Germline transcription and expression of Tcrb-V8 genes in peripheral mouse lymphoid tissues', Immunogenetics, 42, pp. 309 - 314,

Journal articles | 1994

Ho ESP; Jolly CJ; O'Neill HC, 1994, 'Analysis of oncogenic progression in a radiation leukemia virus model', Leukemia, 8, pp. 1202 - 1213

Journal articles | 1994

RAHMAN S; JOLLY CJ; SKERRITT JH; WALLOSHECK A, 1994, 'Cloning of a wheat 15‐kDa grain softness protein (GSP): GSP is a mixture of puroindoline‐like polypeptides', European Journal of Biochemistry, 223, pp. 917 - 925,

Journal articles | 1993

Jolly CJ; Rahman S; Kortt AA; Higgins TJV, 1993, 'Characterisation of the wheat Mr 15000 "grain-softness protein" and analysis of the relationship between its accumulation in the whole seed and grain softness', Theoretical and Applied Genetics, 86, pp. 589 - 597,

Journal articles | 1992

O'Neill HC; Jolly C, 1992, 'Retroviral superantigens', Immunology Today, 13, pp. 462 - 463,

Journal articles | 1987

Jolly CJ; Reid JB; Ross JJ, 1987, 'Internode length in Pisum. Action of gene lw', Physiologia Plantarum, 69, pp. 489 - 498,
Preprints | 2024

Thoms JAI; Yan F; Hampton HR; Davidson S; Joshi S; Saw J; Sarowar CH; Lim XY; Nunez AC; Kakadia PM; Bhuyan GS; Zou X; Nguyen M; Ghodousi ES; Koch FC; Vafaee F; Pickford R; Raftery MJ; Hough S; Buckland G; Bailey M; Ghodke Y; Absar N; Vaughan L; Pasalic L; Fong CY; Kenealy M; Hiwase DK; Stoddart RI; Mohammed S; Lee L; Passam FH; Larsen SR; Spring KJ; Skarratt KK; Rebeiro P; Presgrave P; Stevenson WS; Ling S; Tiley C; Fuller SJ; Roncolato F; Enjeti AK; Hoenemann D; Lemech C; Jolly CJ; Bohlander SK; Curtis DJ; Wong JWH; Unnikrishnan A; Hertzberg M; Olivier J; Polizzotto MN; Pimanda JE, 2024, Clinical Response to Azacitidine in Myelodysplastic Neoplasms is Associated with Distinct DNA Methylation Changes in Haematopoietic Stem and Progenitor cellsin vivo,

Preprints | 2024

Truong P; Shen S; Joshi S; Islam MI; Zhong L; Raftery MJ; Afrasiabi A; Alinejad-Rokny H; Nguyen M; Zou X; Bhuyan GS; Sarowar CH; Ghodousi ES; Stonehouse O; Mohamed S; Toscan CE; Connerty P; Kakadia PM; Bohlander SK; Michie KA; Larsson J; Lock RB; Walkley CR; Thoms JAI; Jolly CJ; Pimanda JE, 2024, Genome-Wide CRISPR-Cas9 Screening Identifies a Synergy between Hypomethylating Agents and SUMOylation Blockade in MDS/AML,

Preprints | 2022

Schnegg-Kaufmann A; Thoms J; Bhuyan GS; Hampton H; Vaughan L; Rutherford K; Kakadia P; Johansson E; Failes T; Arndt G; Koval J; Lindeman R; Warburton P; Rodriguez-Meira A; Mead A; Unnikrishnan A; Bohlander S; Papaemmanuil E; Faridani O; Jolly C; Zanini F; Pimanda J, 2022, Single cell genotyping of matched bone marrow and peripheral blood cells in treatment naive and AZA-treated MDS and CMML,

Conference Abstracts | 2022

Truong P; Shen S; Joshi S; Afrasiabi A; Zhong L; Raftery MJ; Larsson J; Lock RB; Walkley CR; Rokny HA; Thoms JAI; Jolly CJ; Pimanda JE, 2022, 'Genome-Wide CRISPR-Cas9 Screening Identifies a Synergy between Hypomethylating Agents and Sumoylation Blockade in Myelodysplastic Syndromes and Acute Myeloid Leukemia', in BLOOD, AMER SOC HEMATOLOGY, LA, New Orleans, Vol. 140, presented at 64th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), LA, New Orleans, 10 December 2022 - 13 December 2022,

Preprints | 2021

Michel AO; Donovan TA; Roediger B; Lee Q; Jolly C; Monette S, 2021, Chaphamaparvovirus Antigen and Nucleic Acids are not Detected in Kidney Tissues from Cats with Chronic Renal Disease or Immunosuppressive Diseases,

Conference Papers | 2012

Jolly C; Sharbeen G; Yee C; Smith A, 2012, 'Processing of AID-induced uracils in distinct cell cycle phases', in JOURNAL OF IMMUNOLOGY, AMER ASSOC IMMUNOLOGISTS, MA, Boston, presented at 99th Annual Meeting of the American-Association-of-Immunologists, MA, Boston, 04 May 2012 - 08 May 2012,

Conference Papers | 2001

Sale JE; Bemark M; Williams GT; Jolly CJ; Ehrenstein MR; Rada C; Milstein C; Neuberger MS, 2001, 'In vivo and in vitro studies of immunoglobulin gene somatic hypermutation', in Philosophical Transactions of the Royal Society B: Biological Sciences, pp. 21 - 28

Conference Papers | 2000

Jolly C; Kohonen-Corish M; Hodgkin P; Deenick E, 2000, 'MSH2-deficiency reduces the rate of switching to all mouse isotypes without altering the regulation of switching by cell division number', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, pp. A1046 - A1046,

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